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PRRC2B (proline rich coiled-coil 2B)

Identity

Alias (NCBI)BAT2L
BAT2L1
KIAA0515
LQFBS-1
HGNC (Hugo) PRRC2B
HGNC Alias symbMGC10526
LQFBS-1
HGNC Previous nameKIAA0515
 BAT2L
 BAT2L1
HGNC Previous nameKIAA0515
 HLA-B associated transcript 2-like
 HLA-B associated transcript 2-like 1
 proline-rich coiled-coil 2B
LocusID (NCBI) 84726
Atlas_Id 54558
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 131430090 and ends at 131500188 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLEC18A (16q22.1) / PRRC2B (9q34.13)MAPKAP1 (9q33.3) / PRRC2B (9q34.13)PRRC2B (9q34.13) / COPZ1 (12q13.13)
PRRC2B (9q34.13) / CREB3L1 (11p11.2)PRRC2B (9q34.13) / CSH1 (17q23.3)PRRC2B (9q34.13) / GRK5 (10q26.11)
PRRC2B (9q34.13) / HTR3C (3q27.1)PRRC2B (9q34.13) / MGMT (10q26.3)PRRC2B (9q34.13) / NCOR2 (12q24.31)
PRRC2B (9q34.13) / NUP155 (5p13.2)PRRC2B (9q34.13) / NUP214 (9q34.13)PRRC2B (9q34.13) / PRRC2B (9q34.13)
PRRC2B (9q34.13) / SET (9q34.11)PRRC2B (9q34.13) / STC1 (8p21.2)PRRC2B (9q34.13) / ZNF333 (19p13.12)
RALGAPA1 (14q13.2) / PRRC2B (9q34.13)SDC1 (2p24.1) / PRRC2B (9q34.13)MAPKAP1 9q33.3 / PRRC2B 9q34.13
PRRC2B 9q34.13 / NUP155 5p13.2PRRC2B 9q34.13 / NUP214 9q34.13PRRC2B 9q34.13 / SET 9q34.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 4 ]
  t(9;9)(q34;q34) ABL1/PRRC2B
t(9;10)(q34;q26) PRRC2B/MGMT
t(9;12)(q34;q13) PCBP2/PRRC2B
t(9;22)(q34;q11) PRRC2B/BCR


External links

 

Nomenclature
HGNC (Hugo)PRRC2B   28121
Cards
Entrez_Gene (NCBI)PRRC2B    proline rich coiled-coil 2B
AliasesBAT2L; BAT2L1; KIAA0515; LQFBS-1
GeneCards (Weizmann)PRRC2B
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr9:131430090-131500188 [Contig_View]  PRRC2B [Vega]
TCGA cBioPortalPRRC2B
AceView (NCBI)PRRC2B
Genatlas (Paris)PRRC2B
SOURCE (Princeton)PRRC2B
Genetics Home Reference (NIH)PRRC2B
Genomic and cartography
GoldenPath hg38 (UCSC)PRRC2B  -     chr9:131430090-131500188 +  9q34.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRRC2B  -     9q34.13   [Description]    (hg19-Feb_2009)
GoldenPathPRRC2B - 9q34.13 [CytoView hg19]  PRRC2B - 9q34.13 [CytoView hg38]
Genome Data Viewer NCBIPRRC2B [Mapview hg19]  
Gene and transcription
Genbank (Entrez)AB011087 AK025675 AK026025 AK026162 AK055916
RefSeq transcript (Entrez)NM_001384818 NM_001384821 NM_001384822 NM_001384823 NM_013318 NM_032640
Consensus coding sequences : CCDS (NCBI)PRRC2B
Gene ExpressionPRRC2B [ NCBI-GEO ]   PRRC2B [ EBI - ARRAY_EXPRESS ]   PRRC2B [ SEEK ]   PRRC2B [ MEM ]
Gene Expression Viewer (FireBrowse)PRRC2B [ Firebrowse - Broad ]
GenevisibleExpression of PRRC2B in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84726
GTEX Portal (Tissue expression)PRRC2B
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JSZ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JSZ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JSZ5
PhosPhoSitePlusQ5JSZ5
Domains : Interpro (EBI)BAT2_N    PRRC2   
Domain families : Pfam (Sanger)BAT2_N (PF07001)   
Domain families : Pfam (NCBI)pfam07001   
Conserved Domain (NCBI)PRRC2B
SuperfamilyQ5JSZ5
AlphaFold pdb e-kbQ5JSZ5   
Protein Interaction databases
DIP (DOE-UCLA)Q5JSZ5
IntAct (EBI)Q5JSZ5
BioGRIDPRRC2B
STRING (EMBL)PRRC2B
ZODIACPRRC2B
Ontologies - Pathways
QuickGOQ5JSZ5
Ontology : AmiGORNA binding  protein binding  cell differentiation  
Ontology : EGO-EBIRNA binding  protein binding  cell differentiation  
NDEx NetworkPRRC2B
Atlas of Cancer Signalling NetworkPRRC2B
Wikipedia pathwaysPRRC2B
Orthology - Evolution
OrthoDB84726
Phylogenetic Trees/Animal Genes : TreeFamPRRC2B
Homologs : HomoloGenePRRC2B
Homology/Alignments : Family Browser (UCSC)PRRC2B
Gene fusions - Rearrangements
Fusion : MitelmanMAPKAP1/PRRC2B [9q33.3/9q34.13]  
Fusion : MitelmanPRRC2B/MGMT [9q34.13/10q26.3]  
Fusion : MitelmanPRRC2B/NUP155 [9q34.13/5p13.2]  
Fusion : MitelmanPRRC2B/NUP214 [9q34.13/9q34.13]  
Fusion : MitelmanPRRC2B/SET [9q34.13/9q34.11]  
Fusion : QuiverPRRC2B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRRC2B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRRC2B
dbVarPRRC2B
ClinVarPRRC2B
MonarchPRRC2B
1000_GenomesPRRC2B 
Exome Variant ServerPRRC2B
Varsome BrowserPRRC2B
ACMGPRRC2B variants
VarityQ5JSZ5
Genomic Variants (DGV)PRRC2B [DGVbeta]
DECIPHERPRRC2B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRRC2B 
Mutations
ICGC Data PortalPRRC2B 
TCGA Data PortalPRRC2B 
Broad Tumor PortalPRRC2B
OASIS PortalPRRC2B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRRC2B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPRRC2B
Mutations and Diseases : HGMDPRRC2B
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPRRC2B
DgiDB (Drug Gene Interaction Database)PRRC2B
DoCM (Curated mutations)PRRC2B
CIViC (Clinical Interpretations of Variants in Cancer)PRRC2B
Cancer3DPRRC2B
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPRRC2B
MedgenPRRC2B
Genetic Testing Registry PRRC2B
NextProtQ5JSZ5 [Medical]
GENETestsPRRC2B
Target ValidationPRRC2B
Huge Navigator PRRC2B [HugePedia]
ClinGenPRRC2B
Clinical trials, drugs, therapy
MyCancerGenomePRRC2B
Protein Interactions : CTDPRRC2B
Pharm GKB GenePA165585468
PharosQ5JSZ5
Clinical trialPRRC2B
Miscellaneous
canSAR (ICR)PRRC2B
HarmonizomePRRC2B
DataMed IndexPRRC2B
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPRRC2B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:27:04 CEST 2021

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