PRRX1 (paired related homeobox 1)

2003-02-01  

Identity

HGNC
LOCATION
1q24.2
LOCUSID
ALIAS
AGOTC,PHOX1,PMX1,PRX-1,PRX1
FUSION GENES

Other Information

Locus ID:

NCBI: 5396
MIM: 167420
HGNC: 9142
Ensembl: ENSG00000116132

Variants:

dbSNP: 5396
ClinVar: 5396
TCGA: ENSG00000116132
COSMIC: PRRX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000116132ENST00000239461P54821
ENSG00000116132ENST00000367760P54821
ENSG00000116132ENST00000497230G3V2N3

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
232011632012Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.320
232011632012Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.320
247053962014MiR-124 Radiosensitizes human colorectal cancer cells by targeting PRRX1.35
254283932015PRRX1 promotes epithelial-mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer.32
249460102014The roles of the epithelial-mesenchymal transition marker PRRX1 and miR-146b-5p in papillary thyroid carcinoma progression.29
238071602013Paired related homoeobox 1, a new EMT inducer, is involved in metastasis and poor prognosis in colorectal cancer.24
267730052016Prrx1 isoform switching regulates pancreatic cancer invasion and metastatic colonization.23
189786782008Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.21
206348912010Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.18
268201022016miR-655 suppresses epithelial-to-mesenchymal transition by targeting Prrx1 in triple-negative breast cancer.17

Citation

Dessen P

PRRX1 (paired related homeobox 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/224/prrx1