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PRSS16 (protease, serine 16)

Identity

Alias_symbol (synonym)TSSP
Other alias
HGNC (Hugo) PRSS16
LocusID (NCBI) 10279
Atlas_Id 72302
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27247723 and ends at 27256620 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS16   9480
Cards
Entrez_Gene (NCBI)PRSS16  10279  protease, serine 16
AliasesTSSP
GeneCards (Weizmann)PRSS16
Ensembl hg19 (Hinxton)ENSG00000112812 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112812 [Gene_View]  ENSG00000112812 [Sequence]  chr6:27247723-27256620 [Contig_View]  PRSS16 [Vega]
ICGC DataPortalENSG00000112812
TCGA cBioPortalPRSS16
AceView (NCBI)PRSS16
Genatlas (Paris)PRSS16
WikiGenes10279
SOURCE (Princeton)PRSS16
Genetics Home Reference (NIH)PRSS16
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS16  -     chr6:27247723-27256620 +  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS16  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblPRSS16 - 6p22.1 [CytoView hg19]  PRSS16 - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIPRSS16 [Mapview hg19]  PRSS16 [Mapview hg38]
OMIM607169   
Gene and transcription
Genbank (Entrez)AA580758 AF052514 AK093590 AK097918 AK098033
RefSeq transcript (Entrez)NM_005865
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS16
Cluster EST : UnigeneHs.274407 [ NCBI ]
CGAP (NCI)Hs.274407
Alternative Splicing GalleryENSG00000112812
Gene ExpressionPRSS16 [ NCBI-GEO ]   PRSS16 [ EBI - ARRAY_EXPRESS ]   PRSS16 [ SEEK ]   PRSS16 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10279
GTEX Portal (Tissue expression)PRSS16
Human Protein AtlasENSG00000112812-PRSS16 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NQE7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NQE7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NQE7
Splice isoforms : SwissVarQ9NQE7
Catalytic activity : Enzyme3.4.-.- [ Enzyme-Expasy ]   3.4.-.-3.4.-.- [ IntEnz-EBI ]   3.4.-.- [ BRENDA ]   3.4.-.- [ KEGG ]   
PhosPhoSitePlusQ9NQE7
Domains : Interpro (EBI)AB_hydrolase    Peptidase_S28   
Domain families : Pfam (Sanger)Peptidase_S28 (PF05577)   
Domain families : Pfam (NCBI)pfam05577   
Conserved Domain (NCBI)PRSS16
DMDM Disease mutations10279
Blocks (Seattle)PRSS16
SuperfamilyQ9NQE7
Human Protein Atlas [tissue]ENSG00000112812-PRSS16 [tissue]
Peptide AtlasQ9NQE7
HPRD06205
IPIIPI00015573   IPI00385293   IPI00903194   IPI00909787   IPI01018061   IPI00385292   IPI00945448   IPI00945111   
Protein Interaction databases
DIP (DOE-UCLA)Q9NQE7
IntAct (EBI)Q9NQE7
FunCoupENSG00000112812
BioGRIDPRSS16
STRING (EMBL)PRSS16
ZODIACPRSS16
Ontologies - Pathways
QuickGOQ9NQE7
Ontology : AmiGOlysosome  endosome  proteolysis  serine-type peptidase activity  protein catabolic process  
Ontology : EGO-EBIlysosome  endosome  proteolysis  serine-type peptidase activity  protein catabolic process  
Pathways : KEGGBiotin metabolism    Lysine degradation   
NDEx NetworkPRSS16
Atlas of Cancer Signalling NetworkPRSS16
Wikipedia pathwaysPRSS16
Orthology - Evolution
OrthoDB10279
GeneTree (enSembl)ENSG00000112812
Phylogenetic Trees/Animal Genes : TreeFamPRSS16
HOVERGENQ9NQE7
HOGENOMQ9NQE7
Homologs : HomoloGenePRSS16
Homology/Alignments : Family Browser (UCSC)PRSS16
Gene fusions - Rearrangements
Fusion : QuiverPRSS16
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS16
dbVarPRSS16
ClinVarPRSS16
1000_GenomesPRSS16 
Exome Variant ServerPRSS16
ExAC (Exome Aggregation Consortium)ENSG00000112812
GNOMAD BrowserENSG00000112812
Varsome BrowserPRSS16
Genetic variants : HAPMAP10279
Genomic Variants (DGV)PRSS16 [DGVbeta]
DECIPHERPRSS16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS16 
Mutations
ICGC Data PortalPRSS16 
TCGA Data PortalPRSS16 
Broad Tumor PortalPRSS16
OASIS PortalPRSS16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS16
DgiDB (Drug Gene Interaction Database)PRSS16
DoCM (Curated mutations)PRSS16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS16 (select a term)
intoGenPRSS16
Cancer3DPRSS16(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607169   
Orphanet
DisGeNETPRSS16
MedgenPRSS16
Genetic Testing Registry PRSS16
NextProtQ9NQE7 [Medical]
TSGene10279
GENETestsPRSS16
Target ValidationPRSS16
Huge Navigator PRSS16 [HugePedia]
snp3D : Map Gene to Disease10279
BioCentury BCIQPRSS16
ClinGenPRSS16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10279
Chemical/Pharm GKB GenePA33832
Clinical trialPRSS16
Miscellaneous
canSAR (ICR)PRSS16 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS16
EVEXPRSS16
GoPubMedPRSS16
iHOPPRSS16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:25:23 CEST 2018

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