PRSS16 (serine protease 16)

2014-11-01 Affiliation

Identity

HGNC

PRSS16

LOCATION

6p22.1

LOCUSID

10279

ALIAS

TSSP

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 10279
MIM: 607169
HGNC: 9480
Ensembl: ENSG00000112812

Variants:

dbSNP: 10279
ClinVar: 10279
TCGA: ENSG00000112812
COSMIC: PRSS16

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000112812	ENST00000230582	Q9NQE7
ENSG00000112812	ENST00000421826	F2Z2N5
ENSG00000112812	ENST00000454665	B4DZV2
ENSG00000112812	ENST00000466364	F8WF25
ENSG00000112812	ENST00000468930	F8WBG5
ENSG00000112812	ENST00000470870	C9JDN6
ENSG00000112812	ENST00000475106	H0Y8B9
ENSG00000112812	ENST00000485993	H0Y893

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
19571809	2009	Common variants on chromosome 6p22.1 are associated with schizophrenia.	407
22384243	2012	ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2.	36
19295542	2009	Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex.	13
19295542	2009	Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex.	13
22488895	2012	No associations found between the genes situated at 6p22.1, HIST1H2BJ, PRSS16, and PGBD1 in Japanese patients diagnosed with schizophrenia.	4
29061767	2017	Thymic-Specific Serine Protease Limits Central Tolerance and Exacerbates Experimental Autoimmune Encephalomyelitis.	4
12140752	2002	Polymorphisms in the gene encoding thymus-specific serine protease in the extended HLA complex: a potential candidate gene for autoimmune and HLA-associated diseases.	0
17584581	2007	Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease.	0

Citation

Dessen P

PRSS16 (serine protease 16)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72302/prss16