Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PRSS21 (protease, serine, 21 (testisin))

Identity

Other namesESP-1
ESP1
TEST1
TESTISIN
HGNC (Hugo) PRSS21
LocusID (NCBI) 10942
Atlas_Id 41878
Location 16p13.3
Location_base_pair Starts at 2867164 and ends at 2871723 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRSS21   9485
Cards
Entrez_Gene (NCBI)PRSS21  10942  protease, serine, 21 (testisin)
GeneCards (Weizmann)PRSS21
Ensembl hg19 (Hinxton)ENSG00000007038 [Gene_View]  chr16:2867164-2871723 [Contig_View]  PRSS21 [Vega]
Ensembl hg38 (Hinxton)ENSG00000007038 [Gene_View]  chr16:2867164-2871723 [Contig_View]  PRSS21 [Vega]
ICGC DataPortalENSG00000007038
TCGA cBioPortalPRSS21
AceView (NCBI)PRSS21
Genatlas (Paris)PRSS21
WikiGenes10942
SOURCE (Princeton)PRSS21
Genomic and cartography
GoldenPath hg19 (UCSC)PRSS21  -     chr16:2867164-2871723 +  16p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRSS21  -     16p13.3   [Description]    (hg38-Dec_2013)
EnsemblPRSS21 - 16p13.3 [CytoView hg19]  PRSS21 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIPRSS21 [Mapview hg19]  PRSS21 [Mapview hg38]
OMIM608159   
Gene and transcription
Genbank (Entrez)AA860356 AB031329 AB031330 AB031331 AF058300
RefSeq transcript (Entrez)NM_001270452 NM_006799 NM_144956 NM_144957
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010393 NW_004929400
Consensus coding sequences : CCDS (NCBI)PRSS21
Cluster EST : UnigeneHs.72026 [ NCBI ]
CGAP (NCI)Hs.72026
Alternative Splicing : Fast-db (Paris)GSHG0010879
Alternative Splicing GalleryENSG00000007038
Gene ExpressionPRSS21 [ NCBI-GEO ]     PRSS21 [ SEEK ]   PRSS21 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6M0 (Uniprot)
NextProtQ9Y6M0  [Medical]
With graphics : InterProQ9Y6M0
Splice isoforms : SwissVarQ9Y6M0 (Swissvar)
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1    Peptidase_S1_AS    Peptidase_S1A    Trypsin-like_Pept_dom   
Related proteins : CluSTrQ9Y6M0
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
DMDM Disease mutations10942
Blocks (Seattle)Q9Y6M0
Human Protein AtlasENSG00000007038
Peptide AtlasQ9Y6M0
HPRD07082
IPIIPI00305703   IPI00218172   IPI00160581   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6M0
IntAct (EBI)Q9Y6M0
FunCoupENSG00000007038
BioGRIDPRSS21
IntegromeDBPRSS21
STRING (EMBL)PRSS21
Ontologies - Pathways
QuickGOQ9Y6M0
Ontology : AmiGOserine-type endopeptidase activity  protein binding  cytoplasm  plasma membrane  proteolysis  spermatogenesis  serine-type peptidase activity  membrane  anchored component of membrane  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  cytoplasm  plasma membrane  proteolysis  spermatogenesis  serine-type peptidase activity  membrane  anchored component of membrane  
Protein Interaction DatabasePRSS21
DoCM (Curated mutations)PRSS21
Wikipedia pathwaysPRSS21
Gene fusion - Rearrangements
Gene fusion: TCGA
Polymorphisms : SNP, variants
NCBI Variation ViewerPRSS21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS21
dbVarPRSS21
ClinVarPRSS21
1000_GenomesPRSS21 
Exome Variant ServerPRSS21
SNP (GeneSNP Utah)PRSS21
SNP : HGBasePRSS21
Genetic variants : HAPMAPPRSS21
Genomic Variants (DGV)PRSS21 [DGVbeta]
Mutations
ICGC Data PortalPRSS21 
TCGA Data PortalPRSS21 
Tumor PortalPRSS21
Somatic Mutations in Cancer : COSMICPRSS21 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:2867164-2871723
CONAN: Copy Number AnalysisPRSS21 
Mutations and Diseases : HGMDPRSS21
OMIM608159   
MedgenPRSS21
NextProtQ9Y6M0 [Medical]
GENETestsPRSS21
Disease Genetic AssociationPRSS21
Huge Navigator PRSS21 [HugePedia]  PRSS21 [HugeCancerGEM]
snp3D : Map Gene to Disease10942
DGIdb (Drug Gene Interaction db)PRSS21
General knowledge
Homologs : HomoloGenePRSS21
Homology/Alignments : Family Browser (UCSC)PRSS21
Phylogenetic Trees/Animal Genes : TreeFamPRSS21
Chemical/Protein Interactions : CTD10942
Chemical/Pharm GKB GenePA33834
Clinical trialPRSS21
Cancer Resource (Charite)ENSG00000007038
Other databases
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
CoreMinePRSS21
GoPubMedPRSS21
iHOPPRSS21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Apr 13 15:03:52 CEST 2015

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.