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PRSS21 (protease, serine, 21 (testisin))

Identity

Other namesESP-1
ESP1
TEST1
TESTISIN
HGNC (Hugo) PRSS21
LocusID (NCBI) 10942
Location 16p13.3
Location_base_pair Starts at 2867164 and ends at 2871723 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PRSS21   9485
Cards
Entrez_Gene (NCBI)PRSS21  10942  protease, serine, 21 (testisin)
GeneCards (Weizmann)PRSS21
Ensembl (Hinxton)ENSG00000007038 [Gene_View]  chr16:2867164-2871723 [Contig_View]  PRSS21 [Vega]
ICGC DataPortalENSG00000007038
cBioPortalPRSS21
AceView (NCBI)PRSS21
Genatlas (Paris)PRSS21
WikiGenes10942
SOURCE (Princeton)NM_001270452 NM_006799 NM_144956 NM_144957
Genomic and cartography
GoldenPath (UCSC)PRSS21  -  16p13.3   chr16:2867164-2871723 +  16p13.3   [Description]    (hg19-Feb_2009)
EnsemblPRSS21 - 16p13.3 [CytoView]
Mapping of homologs : NCBIPRSS21 [Mapview]
OMIM608159   
Gene and transcription
Genbank (Entrez)AA860356 AB031329 AB031330 AB031331 AF058300
RefSeq transcript (Entrez)NM_001270452 NM_006799 NM_144956 NM_144957
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NT_010393 NW_001838341 NW_004929400
Consensus coding sequences : CCDS (NCBI)PRSS21
Cluster EST : UnigeneHs.72026 [ NCBI ]
CGAP (NCI)Hs.72026
Alternative Splicing : Fast-db (Paris)GSHG0010879
Alternative Splicing GalleryENSG00000007038
Gene ExpressionPRSS21 [ NCBI-GEO ]     PRSS21 [ SEEK ]   PRSS21 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6M0 (Uniprot)
NextProtQ9Y6M0  [Medical]
With graphics : InterProQ9Y6M0
Splice isoforms : SwissVarQ9Y6M0 (Swissvar)
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1 [organisation]   Peptidase_S1_AS [organisation]   Peptidase_S1A [organisation]   Trypsin-like_Pept_dom [organisation]  
Related proteins : CluSTrQ9Y6M0
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
DMDM Disease mutations10942
Blocks (Seattle)Q9Y6M0
Human Protein AtlasENSG00000007038 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9Y6M0
HPRD07082
IPIIPI00305703   IPI00218172   IPI00160581   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6M0
IntAct (EBI)Q9Y6M0
FunCoupENSG00000007038
BioGRIDPRSS21
InParanoidQ9Y6M0
Interologous Interaction database Q9Y6M0
IntegromeDBPRSS21
STRING (EMBL)PRSS21
Ontologies - Pathways
Ontology : AmiGOserine-type endopeptidase activity  protein binding  cytoplasm  plasma membrane  proteolysis  spermatogenesis  serine-type peptidase activity  membrane  anchored component of membrane  
Ontology : EGO-EBIserine-type endopeptidase activity  protein binding  cytoplasm  plasma membrane  proteolysis  spermatogenesis  serine-type peptidase activity  membrane  anchored component of membrane  
Protein Interaction DatabasePRSS21
Wikipedia pathwaysPRSS21
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PRSS21
snp3D : Map Gene to Disease10942
SNP (GeneSNP Utah)PRSS21
SNP : HGBasePRSS21
Genetic variants : HAPMAPPRSS21
Exome VariantPRSS21
1000_GenomesPRSS21 
ICGC programENSG00000007038 
Somatic Mutations in Cancer : COSMICPRSS21 
CONAN: Copy Number AnalysisPRSS21 
Mutations and Diseases : HGMDPRSS21
Mutations and Diseases : intOGenPRSS21
Genomic VariantsPRSS21  PRSS21 [DGVbeta]
dbVarPRSS21
ClinVarPRSS21
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM608159   
MedgenPRSS21
GENETestsPRSS21
Disease Genetic AssociationPRSS21
Huge Navigator PRSS21 [HugePedia]  PRSS21 [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePRSS21
Homology/Alignments : Family Browser (UCSC)PRSS21
Phylogenetic Trees/Animal Genes : TreeFamPRSS21
Chemical/Protein Interactions : CTD10942
Chemical/Pharm GKB GenePA33834
Clinical trialPRSS21
Cancer Resource (Charite)ENSG00000007038
Other databases
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
CoreMinePRSS21
iHOPPRSS21
OncoSearchPRSS21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:01:21 CEST 2014

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