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PRSS22 (protease, serine 22)

Identity

Alias_symbol (synonym)hBSSP-4
BSSP-4
SP001LA
Other alias
HGNC (Hugo) PRSS22
LocusID (NCBI) 64063
Atlas_Id 54962
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 2852727 and ends at 2858170 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS22   14368
Cards
Entrez_Gene (NCBI)PRSS22  64063  protease, serine 22
AliasesBSSP-4; SP001LA; hBSSP-4
GeneCards (Weizmann)PRSS22
Ensembl hg19 (Hinxton)ENSG00000005001 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000005001 [Gene_View]  chr16:2852727-2858170 [Contig_View]  PRSS22 [Vega]
ICGC DataPortalENSG00000005001
TCGA cBioPortalPRSS22
AceView (NCBI)PRSS22
Genatlas (Paris)PRSS22
WikiGenes64063
SOURCE (Princeton)PRSS22
Genetics Home Reference (NIH)PRSS22
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS22  -     chr16:2852727-2858170 -  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS22  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblPRSS22 - 16p13.3 [CytoView hg19]  PRSS22 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIPRSS22 [Mapview hg19]  PRSS22 [Mapview hg38]
OMIM609343   
Gene and transcription
Genbank (Entrez)AB010779 AF321182 AK309624 AK310904 AW083723
RefSeq transcript (Entrez)NM_022119
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS22
Cluster EST : UnigeneHs.459709 [ NCBI ]
CGAP (NCI)Hs.459709
Alternative Splicing GalleryENSG00000005001
Gene ExpressionPRSS22 [ NCBI-GEO ]   PRSS22 [ EBI - ARRAY_EXPRESS ]   PRSS22 [ SEEK ]   PRSS22 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS22 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64063
GTEX Portal (Tissue expression)PRSS22
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9GZN4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9GZN4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9GZN4
Splice isoforms : SwissVarQ9GZN4
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ9GZN4
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS22
DMDM Disease mutations64063
Blocks (Seattle)PRSS22
SuperfamilyQ9GZN4
Human Protein AtlasENSG00000005001
Peptide AtlasQ9GZN4
HPRD08336
IPIIPI00005467   
Protein Interaction databases
DIP (DOE-UCLA)Q9GZN4
IntAct (EBI)Q9GZN4
FunCoupENSG00000005001
BioGRIDPRSS22
STRING (EMBL)PRSS22
ZODIACPRSS22
Ontologies - Pathways
QuickGOQ9GZN4
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  proteolysis  serine-type peptidase activity  extrinsic component of plasma membrane  anchored component of plasma membrane  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  proteolysis  serine-type peptidase activity  extrinsic component of plasma membrane  anchored component of plasma membrane  
NDEx NetworkPRSS22
Atlas of Cancer Signalling NetworkPRSS22
Wikipedia pathwaysPRSS22
Orthology - Evolution
OrthoDB64063
GeneTree (enSembl)ENSG00000005001
Phylogenetic Trees/Animal Genes : TreeFamPRSS22
HOVERGENQ9GZN4
HOGENOMQ9GZN4
Homologs : HomoloGenePRSS22
Homology/Alignments : Family Browser (UCSC)PRSS22
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS22
dbVarPRSS22
ClinVarPRSS22
1000_GenomesPRSS22 
Exome Variant ServerPRSS22
ExAC (Exome Aggregation Consortium)PRSS22 (select the gene name)
Genetic variants : HAPMAP64063
Genomic Variants (DGV)PRSS22 [DGVbeta]
DECIPHERPRSS22 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS22 
Mutations
ICGC Data PortalPRSS22 
TCGA Data PortalPRSS22 
Broad Tumor PortalPRSS22
OASIS PortalPRSS22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS22  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS22
DgiDB (Drug Gene Interaction Database)PRSS22
DoCM (Curated mutations)PRSS22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS22 (select a term)
intoGenPRSS22
Cancer3DPRSS22(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609343   
Orphanet
MedgenPRSS22
Genetic Testing Registry PRSS22
NextProtQ9GZN4 [Medical]
TSGene64063
GENETestsPRSS22
Target ValidationPRSS22
Huge Navigator PRSS22 [HugePedia]
snp3D : Map Gene to Disease64063
BioCentury BCIQPRSS22
ClinGenPRSS22
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64063
Chemical/Pharm GKB GenePA33835
Clinical trialPRSS22
Miscellaneous
canSAR (ICR)PRSS22 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS22
EVEXPRSS22
GoPubMedPRSS22
iHOPPRSS22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:51:21 CEST 2017

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