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PRSS38 (protease, serine 38)

Identity

Alias_symbol (synonym)MPN2
Other alias
HGNC (Hugo) PRSS38
LocusID (NCBI) 339501
Atlas_Id 72310
Location 1q42.13  [Link to chromosome band 1q42]
Location_base_pair Starts at 227815717 and ends at 227846470 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS38   29625
Cards
Entrez_Gene (NCBI)PRSS38  339501  protease, serine 38
AliasesMPN2
GeneCards (Weizmann)PRSS38
Ensembl hg19 (Hinxton)ENSG00000185888 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185888 [Gene_View]  chr1:227815717-227846470 [Contig_View]  PRSS38 [Vega]
ICGC DataPortalENSG00000185888
TCGA cBioPortalPRSS38
AceView (NCBI)PRSS38
Genatlas (Paris)PRSS38
WikiGenes339501
SOURCE (Princeton)PRSS38
Genetics Home Reference (NIH)PRSS38
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS38  -     chr1:227815717-227846470 +  1q42.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS38  -     1q42.13   [Description]    (hg19-Feb_2009)
EnsemblPRSS38 - 1q42.13 [CytoView hg19]  PRSS38 - 1q42.13 [CytoView hg38]
Mapping of homologs : NCBIPRSS38 [Mapview hg19]  PRSS38 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA398170 BC130400 BN000131 HQ258179
RefSeq transcript (Entrez)NM_183062
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS38
Cluster EST : UnigeneHs.97604 [ NCBI ]
CGAP (NCI)Hs.97604
Alternative Splicing GalleryENSG00000185888
Gene ExpressionPRSS38 [ NCBI-GEO ]   PRSS38 [ EBI - ARRAY_EXPRESS ]   PRSS38 [ SEEK ]   PRSS38 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS38 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339501
GTEX Portal (Tissue expression)PRSS38
Protein : pattern, domain, 3D structure
UniProt/SwissProtA1L453   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA1L453  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA1L453
Splice isoforms : SwissVarA1L453
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusA1L453
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS38
DMDM Disease mutations339501
Blocks (Seattle)PRSS38
SuperfamilyA1L453
Human Protein AtlasENSG00000185888
Peptide AtlasA1L453
HPRD07134
IPIIPI00337614   
Protein Interaction databases
DIP (DOE-UCLA)A1L453
IntAct (EBI)A1L453
FunCoupENSG00000185888
BioGRIDPRSS38
STRING (EMBL)PRSS38
ZODIACPRSS38
Ontologies - Pathways
QuickGOA1L453
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  proteolysis  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  proteolysis  
NDEx NetworkPRSS38
Atlas of Cancer Signalling NetworkPRSS38
Wikipedia pathwaysPRSS38
Orthology - Evolution
OrthoDB339501
GeneTree (enSembl)ENSG00000185888
Phylogenetic Trees/Animal Genes : TreeFamPRSS38
HOVERGENA1L453
HOGENOMA1L453
Homologs : HomoloGenePRSS38
Homology/Alignments : Family Browser (UCSC)PRSS38
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS38 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS38
dbVarPRSS38
ClinVarPRSS38
1000_GenomesPRSS38 
Exome Variant ServerPRSS38
ExAC (Exome Aggregation Consortium)PRSS38 (select the gene name)
Genetic variants : HAPMAP339501
Genomic Variants (DGV)PRSS38 [DGVbeta]
DECIPHERPRSS38 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS38 
Mutations
ICGC Data PortalPRSS38 
TCGA Data PortalPRSS38 
Broad Tumor PortalPRSS38
OASIS PortalPRSS38 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS38  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS38
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS38
DgiDB (Drug Gene Interaction Database)PRSS38
DoCM (Curated mutations)PRSS38 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS38 (select a term)
intoGenPRSS38
Cancer3DPRSS38(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPRSS38
Genetic Testing Registry PRSS38
NextProtA1L453 [Medical]
TSGene339501
GENETestsPRSS38
Target ValidationPRSS38
Huge Navigator PRSS38 [HugePedia]
snp3D : Map Gene to Disease339501
BioCentury BCIQPRSS38
ClinGenPRSS38
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339501
Chemical/Pharm GKB GenePA165752268
Clinical trialPRSS38
Miscellaneous
canSAR (ICR)PRSS38 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS38
EVEXPRSS38
GoPubMedPRSS38
iHOPPRSS38
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:35:29 CEST 2017

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