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PRSS42 (protease, serine 42)

Identity

Alias_symbol (synonym)TESSP2
Other alias
HGNC (Hugo) PRSS42
LocusID (NCBI) 339906
Atlas_Id 72311
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 46830404 and ends at 46834095 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS42   30716
Cards
Entrez_Gene (NCBI)PRSS42  339906  protease, serine 42
AliasesTESSP2
GeneCards (Weizmann)PRSS42
Ensembl hg19 (Hinxton)ENSG00000178055 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178055 [Gene_View]  chr3:46830404-46834095 [Contig_View]  PRSS42 [Vega]
ICGC DataPortalENSG00000178055
TCGA cBioPortalPRSS42
AceView (NCBI)PRSS42
Genatlas (Paris)PRSS42
WikiGenes339906
SOURCE (Princeton)PRSS42
Genetics Home Reference (NIH)PRSS42
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS42  -     chr3:46830404-46834095 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS42  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblPRSS42 - 3p21.31 [CytoView hg19]  PRSS42 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBIPRSS42 [Mapview hg19]  PRSS42 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ544583 AK092703 BC140233
RefSeq transcript (Entrez)NM_182702
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS42
Cluster EST : UnigeneHs.585127 [ NCBI ]
CGAP (NCI)Hs.585127
Alternative Splicing GalleryENSG00000178055
Gene ExpressionPRSS42 [ NCBI-GEO ]   PRSS42 [ EBI - ARRAY_EXPRESS ]   PRSS42 [ SEEK ]   PRSS42 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS42 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339906
GTEX Portal (Tissue expression)PRSS42
Human Protein AtlasENSG00000178055-PRSS42 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z5A4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z5A4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z5A4
Splice isoforms : SwissVarQ7Z5A4
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ7Z5A4
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS42
DMDM Disease mutations339906
Blocks (Seattle)PRSS42
SuperfamilyQ7Z5A4
Human Protein Atlas [tissue]ENSG00000178055-PRSS42 [tissue]
Peptide AtlasQ7Z5A4
HPRD07156
IPIIPI00335669   IPI00789501   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z5A4
IntAct (EBI)Q7Z5A4
FunCoupENSG00000178055
BioGRIDPRSS42
STRING (EMBL)PRSS42
ZODIACPRSS42
Ontologies - Pathways
QuickGOQ7Z5A4
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  cytoplasm  proteolysis  germ cell development  spermatogenesis  anchored component of plasma membrane  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  cytoplasm  proteolysis  germ cell development  spermatogenesis  anchored component of plasma membrane  
NDEx NetworkPRSS42
Atlas of Cancer Signalling NetworkPRSS42
Wikipedia pathwaysPRSS42
Orthology - Evolution
OrthoDB339906
GeneTree (enSembl)ENSG00000178055
Phylogenetic Trees/Animal Genes : TreeFamPRSS42
HOVERGENQ7Z5A4
HOGENOMQ7Z5A4
Homologs : HomoloGenePRSS42
Homology/Alignments : Family Browser (UCSC)PRSS42
Gene fusions - Rearrangements
Tumor Fusion PortalPRSS42
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS42 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS42
dbVarPRSS42
ClinVarPRSS42
1000_GenomesPRSS42 
Exome Variant ServerPRSS42
ExAC (Exome Aggregation Consortium)ENSG00000178055
GNOMAD BrowserENSG00000178055
Genetic variants : HAPMAP339906
Genomic Variants (DGV)PRSS42 [DGVbeta]
DECIPHERPRSS42 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS42 
Mutations
ICGC Data PortalPRSS42 
TCGA Data PortalPRSS42 
Broad Tumor PortalPRSS42
OASIS PortalPRSS42 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS42  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS42
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS42
DgiDB (Drug Gene Interaction Database)PRSS42
DoCM (Curated mutations)PRSS42 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS42 (select a term)
intoGenPRSS42
Cancer3DPRSS42(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPRSS42
MedgenPRSS42
Genetic Testing Registry PRSS42
NextProtQ7Z5A4 [Medical]
TSGene339906
GENETestsPRSS42
Target ValidationPRSS42
Huge Navigator PRSS42 [HugePedia]
snp3D : Map Gene to Disease339906
BioCentury BCIQPRSS42
ClinGenPRSS42
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339906
Chemical/Pharm GKB GenePA165698214
Clinical trialPRSS42
Miscellaneous
canSAR (ICR)PRSS42 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS42
EVEXPRSS42
GoPubMedPRSS42
iHOPPRSS42
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:08:49 CET 2017

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