Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PRSS46 (protease, serine 46)

Identity

Alias_symbol (synonym)TESSP6
Other alias
HGNC (Hugo) PRSS46
LocusID (NCBI) 100287362
Atlas_Id 72313
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 46719583 and ends at 46736431 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS46   37325
Cards
Entrez_Gene (NCBI)PRSS46  100287362  protease, serine 46
AliasesTESSP6
GeneCards (Weizmann)PRSS46
Ensembl hg19 (Hinxton)ENSG00000261603 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000261603 [Gene_View]  chr3:46719583-46736431 [Contig_View]  PRSS46 [Vega]
ICGC DataPortalENSG00000261603
TCGA cBioPortalPRSS46
AceView (NCBI)PRSS46
Genatlas (Paris)PRSS46
WikiGenes100287362
SOURCE (Princeton)PRSS46
Genetics Home Reference (NIH)PRSS46
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS46  -     chr3:46719583-46736431 -  3p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS46  -     3p21.31   [Description]    (hg19-Feb_2009)
EnsemblPRSS46 - 3p21.31 [CytoView hg19]  PRSS46 - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBIPRSS46 [Mapview hg19]  PRSS46 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AW183721 DB058077 DB099248 DY654973
RefSeq transcript (Entrez)NM_001205271
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS46
Cluster EST : UnigeneHs.673244 [ NCBI ]
CGAP (NCI)Hs.673244
Alternative Splicing GalleryENSG00000261603
Gene ExpressionPRSS46 [ NCBI-GEO ]   PRSS46 [ EBI - ARRAY_EXPRESS ]   PRSS46 [ SEEK ]   PRSS46 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS46 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)100287362
GTEX Portal (Tissue expression)PRSS46
Human Protein AtlasENSG00000261603-PRSS46 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtE5RG02   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtE5RG02  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProE5RG02
Splice isoforms : SwissVarE5RG02
PhosPhoSitePlusE5RG02
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS46
DMDM Disease mutations100287362
Blocks (Seattle)PRSS46
SuperfamilyE5RG02
Human Protein Atlas [tissue]ENSG00000261603-PRSS46 [tissue]
Peptide AtlasE5RG02
IPIIPI00936578   
Protein Interaction databases
DIP (DOE-UCLA)E5RG02
IntAct (EBI)E5RG02
FunCoupENSG00000261603
BioGRIDPRSS46
STRING (EMBL)PRSS46
ZODIACPRSS46
Ontologies - Pathways
QuickGOE5RG02
Ontology : AmiGOserine-type endopeptidase activity  proteolysis  
Ontology : EGO-EBIserine-type endopeptidase activity  proteolysis  
NDEx NetworkPRSS46
Atlas of Cancer Signalling NetworkPRSS46
Wikipedia pathwaysPRSS46
Orthology - Evolution
OrthoDB100287362
GeneTree (enSembl)ENSG00000261603
Phylogenetic Trees/Animal Genes : TreeFamPRSS46
HOVERGENE5RG02
HOGENOME5RG02
Homologs : HomoloGenePRSS46
Homology/Alignments : Family Browser (UCSC)PRSS46
Gene fusions - Rearrangements
Fusion: Tumor Portal PRSS46
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS46 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS46
dbVarPRSS46
ClinVarPRSS46
1000_GenomesPRSS46 
Exome Variant ServerPRSS46
ExAC (Exome Aggregation Consortium)ENSG00000261603
GNOMAD BrowserENSG00000261603
Genetic variants : HAPMAP100287362
Genomic Variants (DGV)PRSS46 [DGVbeta]
DECIPHERPRSS46 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS46 
Mutations
ICGC Data PortalPRSS46 
TCGA Data PortalPRSS46 
Broad Tumor PortalPRSS46
OASIS PortalPRSS46 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPRSS46
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS46
DgiDB (Drug Gene Interaction Database)PRSS46
DoCM (Curated mutations)PRSS46 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS46 (select a term)
intoGenPRSS46
Cancer3DPRSS46(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPRSS46
Genetic Testing Registry PRSS46
NextProtE5RG02 [Medical]
TSGene100287362
GENETestsPRSS46
Target ValidationPRSS46
Huge Navigator PRSS46 [HugePedia]
snp3D : Map Gene to Disease100287362
BioCentury BCIQPRSS46
ClinGenPRSS46
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD100287362
Chemical/Pharm GKB GenePA165698375
Clinical trialPRSS46
Miscellaneous
canSAR (ICR)PRSS46 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS46
EVEXPRSS46
GoPubMedPRSS46
iHOPPRSS46
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:23:53 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.