PRSS50 (serine protease 50)

2009-11-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
CT20,TSP50
FUSION GENES

Other Information

Locus ID:

NCBI: 29122
MIM: 607950
HGNC: 17910
Ensembl: ENSG00000283706

Variants:

dbSNP: 29122
ClinVar: 29122
TCGA: ENSG00000283706
COSMIC: PRSS50

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000283706ENST00000315170A0A140VJY3

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
336303902021TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).14
339565302021miR-4709-3p Inhibits Cell Proliferation by Downregulating TSP50 Expression in Breast Cancer Cells.1
340169612021TSP50 promotes the Warburg effect and hepatocyte proliferation via regulating PKM2 acetylation.11
347445212021Expression of TSP50, SERCA2 and IL-8 in Colorectal Adenoma and Carcinoma: Correlation to Clinicopathological Factors.0
336303902021TSP50 promotes hepatocyte proliferation and tumour formation by activating glucose-6-phosphate dehydrogenase (G6PD).14
339565302021miR-4709-3p Inhibits Cell Proliferation by Downregulating TSP50 Expression in Breast Cancer Cells.1
340169612021TSP50 promotes the Warburg effect and hepatocyte proliferation via regulating PKM2 acetylation.11
347445212021Expression of TSP50, SERCA2 and IL-8 in Colorectal Adenoma and Carcinoma: Correlation to Clinicopathological Factors.0
293619142018Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer.19
293619142018Testes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer.19
286317092017[Cancer-testis genes in colon cancer].3
286504732017Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.6
286317092017[Cancer-testis genes in colon cancer].3
286504732017Testes-specific protease 50 promotes cell proliferation via inhibiting activin signaling.6
27039397201625-methoxyl-dammarane-3β, 12β, 20-triol and artemisinin synergistically inhibit MDA-MB-231 cell proliferation through downregulation of testes-specific protease 50 (TSP50) expression.3

Citation

Dessen P

PRSS50 (serine protease 50)

Atlas Genet Cytogenet Oncol Haematol. 2009-11-01

Online version: http://atlasgeneticsoncology.org/gene/51218/prss50