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PRSS53 (protease, serine 53)

Identity

Alias_symbol (synonym)POL3S
Other aliasUNQ308
HGNC (Hugo) PRSS53
LocusID (NCBI) 339105
Atlas_Id 72316
Location 16p11.2  [Link to chromosome band 16p11]
Location_base_pair Starts at 31083424 and ends at 31088809 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PRSS53 (16p11.2) / TBC1D24 (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS53   34407
Cards
Entrez_Gene (NCBI)PRSS53  339105  protease, serine 53
AliasesPOL3S; UNQ308
GeneCards (Weizmann)PRSS53
Ensembl hg19 (Hinxton)ENSG00000151006 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151006 [Gene_View]  chr16:31083424-31088809 [Contig_View]  PRSS53 [Vega]
ICGC DataPortalENSG00000151006
TCGA cBioPortalPRSS53
AceView (NCBI)PRSS53
Genatlas (Paris)PRSS53
WikiGenes339105
SOURCE (Princeton)PRSS53
Genetics Home Reference (NIH)PRSS53
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS53  -     chr16:31083424-31088809 -  16p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS53  -     16p11.2   [Description]    (hg19-Feb_2009)
EnsemblPRSS53 - 16p11.2 [CytoView hg19]  PRSS53 - 16p11.2 [CytoView hg38]
Mapping of homologs : NCBIPRSS53 [Mapview hg19]  PRSS53 [Mapview hg38]
OMIM610561   
Gene and transcription
Genbank (Entrez)AJ627035 AK131087 BC172247 BC172552
RefSeq transcript (Entrez)NM_001039503
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS53
Cluster EST : UnigeneHs.569575 [ NCBI ]
CGAP (NCI)Hs.569575
Alternative Splicing GalleryENSG00000151006
Gene ExpressionPRSS53 [ NCBI-GEO ]   PRSS53 [ EBI - ARRAY_EXPRESS ]   PRSS53 [ SEEK ]   PRSS53 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS53 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)339105
GTEX Portal (Tissue expression)PRSS53
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2L4Q9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2L4Q9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2L4Q9
Splice isoforms : SwissVarQ2L4Q9
Catalytic activity : Enzyme3.4.21.- [ Enzyme-Expasy ]   3.4.21.-3.4.21.- [ IntEnz-EBI ]   3.4.21.- [ BRENDA ]   3.4.21.- [ KEGG ]   
PhosPhoSitePlusQ2L4Q9
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)    TRYPSIN_SER (PS00135)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS    TRYPSIN_SER   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS53
DMDM Disease mutations339105
Blocks (Seattle)PRSS53
SuperfamilyQ2L4Q9
Human Protein AtlasENSG00000151006
Peptide AtlasQ2L4Q9
IPIIPI00553224   
Protein Interaction databases
DIP (DOE-UCLA)Q2L4Q9
IntAct (EBI)Q2L4Q9
FunCoupENSG00000151006
BioGRIDPRSS53
STRING (EMBL)PRSS53
ZODIACPRSS53
Ontologies - Pathways
QuickGOQ2L4Q9
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  cytoplasm  proteolysis  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  cytoplasm  proteolysis  
NDEx NetworkPRSS53
Atlas of Cancer Signalling NetworkPRSS53
Wikipedia pathwaysPRSS53
Orthology - Evolution
OrthoDB339105
GeneTree (enSembl)ENSG00000151006
Phylogenetic Trees/Animal Genes : TreeFamPRSS53
HOVERGENQ2L4Q9
HOGENOMQ2L4Q9
Homologs : HomoloGenePRSS53
Homology/Alignments : Family Browser (UCSC)PRSS53
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS53 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS53
dbVarPRSS53
ClinVarPRSS53
1000_GenomesPRSS53 
Exome Variant ServerPRSS53
ExAC (Exome Aggregation Consortium)PRSS53 (select the gene name)
Genetic variants : HAPMAP339105
Genomic Variants (DGV)PRSS53 [DGVbeta]
DECIPHERPRSS53 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS53 
Mutations
ICGC Data PortalPRSS53 
TCGA Data PortalPRSS53 
Broad Tumor PortalPRSS53
OASIS PortalPRSS53 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS53  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS53
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS53
DgiDB (Drug Gene Interaction Database)PRSS53
DoCM (Curated mutations)PRSS53 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS53 (select a term)
intoGenPRSS53
Cancer3DPRSS53(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610561   
Orphanet
MedgenPRSS53
Genetic Testing Registry PRSS53
NextProtQ2L4Q9 [Medical]
TSGene339105
GENETestsPRSS53
Target ValidationPRSS53
Huge Navigator PRSS53 [HugePedia]
snp3D : Map Gene to Disease339105
BioCentury BCIQPRSS53
ClinGenPRSS53
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD339105
Chemical/Pharm GKB GenePA165450635
Clinical trialPRSS53
Miscellaneous
canSAR (ICR)PRSS53 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS53
EVEXPRSS53
GoPubMedPRSS53
iHOPPRSS53
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:35:30 CEST 2017

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