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PRSS57 (protease, serine 57)

Identity

Alias_namesPRSSL1
protease, serine-like 1
Alias_symbol (synonym)UNQ782
Other aliasNSP4
HGNC (Hugo) PRSS57
LocusID (NCBI) 400668
Atlas_Id 72319
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 685521 and ends at 695461 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS57   31397
Cards
Entrez_Gene (NCBI)PRSS57  400668  protease, serine 57
AliasesNSP4; PRSSL1; UNQ782
GeneCards (Weizmann)PRSS57
Ensembl hg19 (Hinxton)ENSG00000185198 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185198 [Gene_View]  chr19:685521-695461 [Contig_View]  PRSS57 [Vega]
ICGC DataPortalENSG00000185198
TCGA cBioPortalPRSS57
AceView (NCBI)PRSS57
Genatlas (Paris)PRSS57
WikiGenes400668
SOURCE (Princeton)PRSS57
Genetics Home Reference (NIH)PRSS57
Genomic and cartography
GoldenPath hg38 (UCSC)PRSS57  -     chr19:685521-695461 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PRSS57  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblPRSS57 - 19p13.3 [CytoView hg19]  PRSS57 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIPRSS57 [Mapview hg19]  PRSS57 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AY358594 BC137161 BC144505 D19687
RefSeq transcript (Entrez)NM_001308209 NM_214710
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PRSS57
Cluster EST : UnigeneHs.245146 [ NCBI ]
CGAP (NCI)Hs.245146
Alternative Splicing GalleryENSG00000185198
Gene ExpressionPRSS57 [ NCBI-GEO ]   PRSS57 [ EBI - ARRAY_EXPRESS ]   PRSS57 [ SEEK ]   PRSS57 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS57 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)400668
GTEX Portal (Tissue expression)PRSS57
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UWY2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UWY2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UWY2
Splice isoforms : SwissVarQ6UWY2
PhosPhoSitePlusQ6UWY2
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1_PA    Peptidase_S1A    Trypsin_dom    TRYPSIN_HIS   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS57
DMDM Disease mutations400668
Blocks (Seattle)PRSS57
PDB (SRS)4Q7X    4Q7Y    4Q7Z    4Q80   
PDB (PDBSum)4Q7X    4Q7Y    4Q7Z    4Q80   
PDB (IMB)4Q7X    4Q7Y    4Q7Z    4Q80   
PDB (RSDB)4Q7X    4Q7Y    4Q7Z    4Q80   
Structural Biology KnowledgeBase4Q7X    4Q7Y    4Q7Z    4Q80   
SCOP (Structural Classification of Proteins)4Q7X    4Q7Y    4Q7Z    4Q80   
CATH (Classification of proteins structures)4Q7X    4Q7Y    4Q7Z    4Q80   
SuperfamilyQ6UWY2
Human Protein AtlasENSG00000185198
Peptide AtlasQ6UWY2
HPRD17916
IPIIPI00797223   
Protein Interaction databases
DIP (DOE-UCLA)Q6UWY2
IntAct (EBI)Q6UWY2
FunCoupENSG00000185198
BioGRIDPRSS57
STRING (EMBL)PRSS57
ZODIACPRSS57
Ontologies - Pathways
QuickGOQ6UWY2
Ontology : AmiGOserine-type endopeptidase activity  extracellular space  proteolysis  heparin binding  serine-type peptidase activity  azurophil granule lumen  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular space  proteolysis  heparin binding  serine-type peptidase activity  azurophil granule lumen  
NDEx NetworkPRSS57
Atlas of Cancer Signalling NetworkPRSS57
Wikipedia pathwaysPRSS57
Orthology - Evolution
OrthoDB400668
GeneTree (enSembl)ENSG00000185198
Phylogenetic Trees/Animal Genes : TreeFamPRSS57
HOVERGENQ6UWY2
HOGENOMQ6UWY2
Homologs : HomoloGenePRSS57
Homology/Alignments : Family Browser (UCSC)PRSS57
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS57 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS57
dbVarPRSS57
ClinVarPRSS57
1000_GenomesPRSS57 
Exome Variant ServerPRSS57
ExAC (Exome Aggregation Consortium)PRSS57 (select the gene name)
Genetic variants : HAPMAP400668
Genomic Variants (DGV)PRSS57 [DGVbeta]
DECIPHERPRSS57 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPRSS57 
Mutations
ICGC Data PortalPRSS57 
TCGA Data PortalPRSS57 
Broad Tumor PortalPRSS57
OASIS PortalPRSS57 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS57  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS57
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS57
DgiDB (Drug Gene Interaction Database)PRSS57
DoCM (Curated mutations)PRSS57 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS57 (select a term)
intoGenPRSS57
Cancer3DPRSS57(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPRSS57
Genetic Testing Registry PRSS57
NextProtQ6UWY2 [Medical]
TSGene400668
GENETestsPRSS57
Target ValidationPRSS57
Huge Navigator PRSS57 [HugePedia]
snp3D : Map Gene to Disease400668
BioCentury BCIQPRSS57
ClinGenPRSS57
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD400668
Chemical/Pharm GKB GenePA164742285
Clinical trialPRSS57
Miscellaneous
canSAR (ICR)PRSS57 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS57
EVEXPRSS57
GoPubMedPRSS57
iHOPPRSS57
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:37:42 CEST 2017

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