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PRSS58 (protease, serine, 58)

Identity

Alias_symbol (synonym)TRYX3
Other aliasPRSS1
TRY1
UNQ2540
HGNC (Hugo) PRSS58
LocusID (NCBI) 136541
Atlas_Id 72320
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 141951958 and ends at 141957878 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PRSS58   39125
Cards
Entrez_Gene (NCBI)PRSS58  136541  protease, serine, 58
AliasesPRSS1; TRY1; TRYX3; UNQ2540
GeneCards (Weizmann)PRSS58
Ensembl hg19 (Hinxton)ENSG00000258223 [Gene_View]  chr7:141951958-141957878 [Contig_View]  PRSS58 [Vega]
Ensembl hg38 (Hinxton)ENSG00000258223 [Gene_View]  chr7:141951958-141957878 [Contig_View]  PRSS58 [Vega]
ICGC DataPortalENSG00000258223
TCGA cBioPortalPRSS58
AceView (NCBI)PRSS58
Genatlas (Paris)PRSS58
WikiGenes136541
SOURCE (Princeton)PRSS58
Genetics Home Reference (NIH)PRSS58
Genomic and cartography
GoldenPath hg19 (UCSC)PRSS58  -     chr7:141951958-141957878 -  7q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PRSS58  -     7q34   [Description]    (hg38-Dec_2013)
EnsemblPRSS58 - 7q34 [CytoView hg19]  PRSS58 - 7q34 [CytoView hg38]
Mapping of homologs : NCBIPRSS58 [Mapview hg19]  PRSS58 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA625766 AK122940 AY358487 BC035384
RefSeq transcript (Entrez)NM_001001317
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_001333 NT_007933 NT_187562 NW_004929333
Consensus coding sequences : CCDS (NCBI)PRSS58
Cluster EST : UnigeneHs.98609 [ NCBI ]
CGAP (NCI)Hs.98609
Alternative Splicing GalleryENSG00000258223
Gene ExpressionPRSS58 [ NCBI-GEO ]   PRSS58 [ EBI - ARRAY_EXPRESS ]   PRSS58 [ SEEK ]   PRSS58 [ MEM ]
Gene Expression Viewer (FireBrowse)PRSS58 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)136541
GTEX Portal (Tissue expression)PRSS58
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYP2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYP2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYP2
Splice isoforms : SwissVarQ8IYP2
Catalytic activity : Enzyme3.4.21.4 [ Enzyme-Expasy ]   3.4.21.43.4.21.4 [ IntEnz-EBI ]   3.4.21.4 [ BRENDA ]   3.4.21.4 [ KEGG ]   
PhosPhoSitePlusQ8IYP2
Domaine pattern : Prosite (Expaxy)TRYPSIN_DOM (PS50240)    TRYPSIN_HIS (PS00134)   
Domains : Interpro (EBI)Peptidase_S1    Peptidase_S1_AS    Peptidase_S1A    Trypsin-like_Pept_dom   
Domain families : Pfam (Sanger)Trypsin (PF00089)   
Domain families : Pfam (NCBI)pfam00089   
Domain families : Smart (EMBL)Tryp_SPc (SM00020)  
Conserved Domain (NCBI)PRSS58
DMDM Disease mutations136541
Blocks (Seattle)PRSS58
SuperfamilyQ8IYP2
Human Protein AtlasENSG00000258223
Peptide AtlasQ8IYP2
HPRD15572
IPIIPI00217821   
Protein Interaction databases
DIP (DOE-UCLA)Q8IYP2
IntAct (EBI)Q8IYP2
FunCoupENSG00000258223
BioGRIDPRSS58
STRING (EMBL)PRSS58
ZODIACPRSS58
Ontologies - Pathways
QuickGOQ8IYP2
Ontology : AmiGOserine-type endopeptidase activity  extracellular region  proteolysis  
Ontology : EGO-EBIserine-type endopeptidase activity  extracellular region  proteolysis  
NDEx NetworkPRSS58
Atlas of Cancer Signalling NetworkPRSS58
Wikipedia pathwaysPRSS58
Orthology - Evolution
OrthoDB136541
GeneTree (enSembl)ENSG00000258223
Phylogenetic Trees/Animal Genes : TreeFamPRSS58
HOVERGENQ8IYP2
HOGENOMQ8IYP2
Homologs : HomoloGenePRSS58
Homology/Alignments : Family Browser (UCSC)PRSS58
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPRSS58 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PRSS58
dbVarPRSS58
ClinVarPRSS58
1000_GenomesPRSS58 
Exome Variant ServerPRSS58
ExAC (Exome Aggregation Consortium)PRSS58 (select the gene name)
Genetic variants : HAPMAP136541
Genomic Variants (DGV)PRSS58 [DGVbeta]
DECIPHER (Syndromes)7:141951958-141957878  ENSG00000258223
CONAN: Copy Number AnalysisPRSS58 
Mutations
ICGC Data PortalPRSS58 
TCGA Data PortalPRSS58 
Broad Tumor PortalPRSS58
OASIS PortalPRSS58 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPRSS58  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPRSS58
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PRSS58
DgiDB (Drug Gene Interaction Database)PRSS58
DoCM (Curated mutations)PRSS58 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PRSS58 (select a term)
intoGenPRSS58
Cancer3DPRSS58(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPRSS58
Genetic Testing Registry PRSS58
NextProtQ8IYP2 [Medical]
TSGene136541
GENETestsPRSS58
Huge Navigator PRSS58 [HugePedia]
snp3D : Map Gene to Disease136541
BioCentury BCIQPRSS58
ClinGenPRSS58
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD136541
Clinical trialPRSS58
Miscellaneous
canSAR (ICR)PRSS58 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePRSS58
EVEXPRSS58
GoPubMedPRSS58
iHOPPRSS58
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:40:01 CET 2017

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