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PSAT1 (phosphoserine aminotransferase 1)

Identity

Alias_symbol (synonym)PSA
Other aliasEPIP
NLS2
PSAT
PSATD
HGNC (Hugo) PSAT1
LocusID (NCBI) 29968
Atlas_Id 50075
Location 9q21.2  [Link to chromosome band 9q21]
Location_base_pair Starts at 78297075 and ends at 78330093 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ANKIB1 (7q21.2) / PSAT1 (9q21.2)CPNE4 (3q22.1) / PSAT1 (9q21.2)PSAT1 (9q21.2) / SLC1A4 (2p14)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSAT1   19129
Cards
Entrez_Gene (NCBI)PSAT1  29968  phosphoserine aminotransferase 1
AliasesEPIP; NLS2; PSA; PSAT; 
PSATD
GeneCards (Weizmann)PSAT1
Ensembl hg19 (Hinxton)ENSG00000135069 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135069 [Gene_View]  chr9:78297075-78330093 [Contig_View]  PSAT1 [Vega]
ICGC DataPortalENSG00000135069
TCGA cBioPortalPSAT1
AceView (NCBI)PSAT1
Genatlas (Paris)PSAT1
WikiGenes29968
SOURCE (Princeton)PSAT1
Genetics Home Reference (NIH)PSAT1
Genomic and cartography
GoldenPath hg38 (UCSC)PSAT1  -     chr9:78297075-78330093 +  9q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSAT1  -     9q21.2   [Description]    (hg19-Feb_2009)
EnsemblPSAT1 - 9q21.2 [CytoView hg19]  PSAT1 - 9q21.2 [CytoView hg38]
Mapping of homologs : NCBIPSAT1 [Mapview hg19]  PSAT1 [Mapview hg38]
OMIM610936   610992   616038   
Gene and transcription
Genbank (Entrez)AF113132 AK025460 AK295222 AK295310 AY131232
RefSeq transcript (Entrez)NM_021154 NM_058179
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSAT1
Cluster EST : UnigeneHs.494261 [ NCBI ]
CGAP (NCI)Hs.494261
Alternative Splicing GalleryENSG00000135069
Gene ExpressionPSAT1 [ NCBI-GEO ]   PSAT1 [ EBI - ARRAY_EXPRESS ]   PSAT1 [ SEEK ]   PSAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)PSAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)29968
GTEX Portal (Tissue expression)PSAT1
Human Protein AtlasENSG00000135069-PSAT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y617   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y617  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y617
Splice isoforms : SwissVarQ9Y617
Catalytic activity : Enzyme2.6.1.52 [ Enzyme-Expasy ]   2.6.1.522.6.1.52 [ IntEnz-EBI ]   2.6.1.52 [ BRENDA ]   2.6.1.52 [ KEGG ]   
PhosPhoSitePlusQ9Y617
Domaine pattern : Prosite (Expaxy)AA_TRANSFER_CLASS_5 (PS00595)   
Domains : Interpro (EBI)Aminotrans_V_dom    Aminotrans_V_PyrdxlP_BS    Pser_aminoTfrase    PyrdxlP-dep_Trfase    PyrdxlP-dep_Trfase_major_sub1    PyrdxlP-dep_Trfase_major_sub2   
Domain families : Pfam (Sanger)Aminotran_5 (PF00266)   
Domain families : Pfam (NCBI)pfam00266   
Conserved Domain (NCBI)PSAT1
DMDM Disease mutations29968
Blocks (Seattle)PSAT1
PDB (SRS)3E77   
PDB (PDBSum)3E77   
PDB (IMB)3E77   
PDB (RSDB)3E77   
Structural Biology KnowledgeBase3E77   
SCOP (Structural Classification of Proteins)3E77   
CATH (Classification of proteins structures)3E77   
SuperfamilyQ9Y617
Human Protein Atlas [tissue]ENSG00000135069-PSAT1 [tissue]
Peptide AtlasQ9Y617
HPRD17918
IPIIPI00219478   IPI00001734   IPI01014011   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y617
IntAct (EBI)Q9Y617
FunCoupENSG00000135069
BioGRIDPSAT1
STRING (EMBL)PSAT1
ZODIACPSAT1
Ontologies - Pathways
QuickGOQ9Y617
Ontology : AmiGOO-phospho-L-serine:2-oxoglutarate aminotransferase activity  O-phospho-L-serine:2-oxoglutarate aminotransferase activity  O-phospho-L-serine:2-oxoglutarate aminotransferase activity  cytoplasm  cytosol  cytosol  L-serine biosynthetic process  L-serine biosynthetic process  L-serine biosynthetic process  pyridoxine biosynthetic process  extracellular exosome  
Ontology : EGO-EBIO-phospho-L-serine:2-oxoglutarate aminotransferase activity  O-phospho-L-serine:2-oxoglutarate aminotransferase activity  O-phospho-L-serine:2-oxoglutarate aminotransferase activity  cytoplasm  cytosol  cytosol  L-serine biosynthetic process  L-serine biosynthetic process  L-serine biosynthetic process  pyridoxine biosynthetic process  extracellular exosome  
Pathways : KEGGGlycine, serine and threonine metabolism    Vitamin B6 metabolism   
NDEx NetworkPSAT1
Atlas of Cancer Signalling NetworkPSAT1
Wikipedia pathwaysPSAT1
Orthology - Evolution
OrthoDB29968
GeneTree (enSembl)ENSG00000135069
Phylogenetic Trees/Animal Genes : TreeFamPSAT1
HOVERGENQ9Y617
HOGENOMQ9Y617
Homologs : HomoloGenePSAT1
Homology/Alignments : Family Browser (UCSC)PSAT1
Gene fusions - Rearrangements
Fusion: Tumor Portal PSAT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSAT1
dbVarPSAT1
ClinVarPSAT1
1000_GenomesPSAT1 
Exome Variant ServerPSAT1
ExAC (Exome Aggregation Consortium)ENSG00000135069
GNOMAD BrowserENSG00000135069
Genetic variants : HAPMAP29968
Genomic Variants (DGV)PSAT1 [DGVbeta]
DECIPHERPSAT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSAT1 
Mutations
ICGC Data PortalPSAT1 
TCGA Data PortalPSAT1 
Broad Tumor PortalPSAT1
OASIS PortalPSAT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSAT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSAT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSAT1
DgiDB (Drug Gene Interaction Database)PSAT1
DoCM (Curated mutations)PSAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSAT1 (select a term)
intoGenPSAT1
Cancer3DPSAT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610936    610992    616038   
Orphanet2439    20609   
MedgenPSAT1
Genetic Testing Registry PSAT1
NextProtQ9Y617 [Medical]
TSGene29968
GENETestsPSAT1
Target ValidationPSAT1
Huge Navigator PSAT1 [HugePedia]
snp3D : Map Gene to Disease29968
BioCentury BCIQPSAT1
ClinGenPSAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD29968
Chemical/Pharm GKB GenePA128395782
Clinical trialPSAT1
Miscellaneous
canSAR (ICR)PSAT1 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSAT1
EVEXPSAT1
GoPubMedPSAT1
iHOPPSAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 13:06:55 CET 2017

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