PSD3 (pleckstrin and Sec7 domain containing 3)

2007-02-01  

Identity

HGNC
LOCATION
8p22
LOCUSID
ALIAS
EFA6D,EFA6R,HCA67
FUSION GENES

Other Information

Locus ID:

NCBI: 23362
MIM: 614440
HGNC: 19093
Ensembl: ENSG00000156011

Variants:

dbSNP: 23362
ClinVar: 23362
TCGA: ENSG00000156011
COSMIC: PSD3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000156011ENST00000286485Q9NYI0
ENSG00000156011ENST00000327040Q9NYI0
ENSG00000156011ENST00000428502B4DKF8
ENSG00000156011ENST00000440756Q9NYI0
ENSG00000156011ENST00000517971E5RH02
ENSG00000156011ENST00000518315E5RFG7
ENSG00000156011ENST00000519851E5RJE4
ENSG00000156011ENST00000520858H0YC20
ENSG00000156011ENST00000521027H0YAQ7
ENSG00000156011ENST00000521475E5RIH3
ENSG00000156011ENST00000523619E5RJ29
ENSG00000156011ENST00000614430A0A087WXD8
ENSG00000156011ENST00000615573A0A087X1Z0

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
200806502010Inherited genetic variant predisposes to aggressive but not indolent prostate cancer.46
162703212005Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival.30
186493582008Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.6
252967582014Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6).6
282378572017Genetic association analysis of polymorphisms in PSD3 gene with obesity, type 2 diabetes, and HDL cholesterol.1

Citation

Dessen P

PSD3 (pleckstrin and Sec7 domain containing 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43654/psd3