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PSENEN (presenilin enhancer 2 homolog (C. elegans))

Identity

Other namesMSTP064
PEN-2
PEN2
HGNC (Hugo) PSENEN
LocusID (NCBI) 55851
Location 19q13.12
Location_base_pair Starts at 36236494 and ends at 36237903 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PSENEN   30100
Entrez_Gene (NCBI)PSENEN  55851  presenilin enhancer 2 homolog (C. elegans)
Cards
GeneCards (Weizmann)PSENEN
Ensembl (Hinxton)ENSG00000205155 [Gene_View]  chr19:36236494-36237903 [Contig_View]  PSENEN [Vega]
AceView (NCBI)PSENEN
Genatlas (Paris)PSENEN
SOURCE (Stanford)NM_172341
Genomic and cartography
GoldenPath (UCSC)PSENEN  -  19q13.12   chr19:36236494-36237903 +  19q13.12   [Description]    (hg19-Feb_2009)
EnsemblPSENEN - 19q13.12 [CytoView]
Mapping of homologs : NCBIPSENEN [Mapview]
OMIM607632   613736   
Gene and transcription
Genbank (Entrez)AF220053 AK312233 BC009575 BQ222622 DQ893095
RefSeq transcript (SRS)NM_172341
RefSeq transcript (Entrez)NM_172341
RefSeq genomic (SRS)AC_000151 NC_000019 NC_018930 NG_027934 NT_011109 NW_001838494 NW_004078099
RefSeq genomic (Entrez)AC_000151 NC_000019 NC_018930 NG_027934 NT_011109 NW_001838494 NW_004078099
Consensus coding sequences : CCDS (NCBI)PSENEN
Cluster EST : UnigeneHs.534465 [ SRS ] Hs.534465 [ NCBI ]
CGAP (NCI)Hs.534465
Alternative Splicing : Fast-db (Paris)GSHG0014842
Alternative Splicing GalleryENSG00000205155
Gene ExpressionPSENEN [ NCBI-GEO ]   PSENEN [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NZ42 (SRS) Q9NZ42 (Uniprot)
NextProtQ9NZ42
With graphics : InterProQ9NZ42
Splice isoforms : SwissVarQ9NZ42(Swissvar)
Domains : Interpro (SRS)Gamma_Secretase_Asp_P_PEN2   
Domains : Interpro (EBI)Gamma_Secretase_Asp_P_PEN2   
Related proteins : CluSTrQ9NZ42
Domain families : Pfam (SRS)PEN-2 (PF10251)   
Domain families : Pfam (Sanger)PEN-2 (PF10251)   
Domain families : Pfam (NCBI)pfam10251   
DMDM55851
Blocks (Seattle)Q9NZ42
Human Protein AtlasENSG00000205155
HPRD06362
IPIIPI00020516   
Protein Interaction databases
DIP (DOE-UCLA)Q9NZ42
IntAct (EBI)Q9NZ42
FunCoupENSG00000205155
REACTOMEPSENEN
Protein Interaction Database55851
BioGRIDPSENEN
InParanoidQ9NZ42
Interologous Interaction database Q9NZ42
IntegromeDBPSENEN
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PSENEN
SNP (GeneSNP Utah)PSENEN
SNP : HGBasePSENEN
Genetic variants : HAPMAPPSENEN
Somatic Mutations in Cancer : COSMICPSENEN 
CONAN: Copy Number AnalysisPSENEN 
Mutations and Diseases : HGMDPSENEN
OMIM607632    613736   
GENETests607632    613736   
Disease Genetic AssociationPSENEN
Huge Navigator PSENEN [HugePedia]  PSENEN [HugeCancerGEM]
Genomic VariantsPSENEN  PSENEN [DGVbeta]
snp3D : Map Gene to Disease55851
General knowledge
Homologs : HomoloGenePSENEN
Homology/Alignments : Family Browser (UCSC)PSENEN
Phylogenetic Trees/Animal Genes : TreeFamPSENEN
Chemical/Protein Interactions : CTD55851
Chemical/Pharm GKB GenePA142671122
Clinical trialPSENEN
Cancer Resource (Charite)ENSG00000205155
Ontology : AmiGOprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  integral to plasma membrane  membrane protein ectodomain proteolysis  apoptotic process  Notch signaling pathway  Notch receptor processing  protein processing  membrane protein intracellular domain proteolysis  Golgi cisterna membrane  amyloid precursor protein catabolic process  positive regulation of catalytic activity  nerve growth factor receptor signaling pathway  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  integral to plasma membrane  membrane protein ectodomain proteolysis  apoptotic process  Notch signaling pathway  Notch receptor processing  protein processing  membrane protein intracellular domain proteolysis  Golgi cisterna membrane  amyloid precursor protein catabolic process  positive regulation of catalytic activity  nerve growth factor receptor signaling pathway  
Pathways : KEGGAlzheimer's diseaseNotch signaling pathway
Other databases
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
PubGenePSENEN
iHOPPSENEN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:48:47 CEST 2013
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