PSG5 (pregnancy specific beta-1-glycoprotein 5)

2014-11-01  

Identity

HGNC
PSG5
LOCATION
19q13.31
LOCUSID
5673
ALIAS
FL-NCA-3,PSG

Other Information

Locus ID:

NCBI: 5673
MIM: 176394
HGNC: 9522
Ensembl: ENSG00000204941

Variants:

dbSNP: 5673
ClinVar: 5673
TCGA: ENSG00000204941
COSMIC: PSG5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204941ENST00000342951Q15238
ENSG00000204941ENST00000342951A0A024R0S1
ENSG00000204941ENST00000366175Q15238
ENSG00000204941ENST00000366175A0A024R0S1
ENSG00000204941ENST00000404580E7EQY3
ENSG00000204941ENST00000407356Q15238
ENSG00000204941ENST00000407356A0A024R0S1
ENSG00000204941ENST00000407568E9PC55
ENSG00000204941ENST00000599812M0R1G9

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Cell surface interactions at the vascular wallREACTOMER-HSA-202733

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
234690022013Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.12
179781292007Placenta-derived, cellular messenger RNA expression in the maternal blood of preeclamptic women.10
165633482006Activation of the human pregnancy-specific glycoprotein PSG-5 promoter by KLF4 and Sp1.5
234184922013PSG gene expression is up-regulated by lysine acetylation involving histone and nonhistone proteins.5

Citation

Dessen P

PSG5 (pregnancy specific beta-1-glycoprotein 5)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/72333/psg5