Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PSMA2 (proteasome subunit alpha 2)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)MU
HC3
PMSA2
Other aliasPSC2
HGNC (Hugo) PSMA2
LocusID (NCBI) 5683
Atlas_Id 55442
Location 7p14.1  [Link to chromosome band 7p14]
Location_base_pair Starts at 42916861 and ends at 42932206 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMA2   9531
Cards
Entrez_Gene (NCBI)PSMA2  5683  proteasome subunit alpha 2
AliasesHC3; MU; PMSA2; PSC2
GeneCards (Weizmann)PSMA2
Ensembl hg19 (Hinxton)ENSG00000106588 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106588 [Gene_View]  chr7:42916861-42932206 [Contig_View]  PSMA2 [Vega]
ICGC DataPortalENSG00000106588
TCGA cBioPortalPSMA2
AceView (NCBI)PSMA2
Genatlas (Paris)PSMA2
WikiGenes5683
SOURCE (Princeton)PSMA2
Genetics Home Reference (NIH)PSMA2
Genomic and cartography
GoldenPath hg38 (UCSC)PSMA2  -     chr7:42916861-42932206 -  7p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMA2  -     7p14.1   [Description]    (hg19-Feb_2009)
EnsemblPSMA2 - 7p14.1 [CytoView hg19]  PSMA2 - 7p14.1 [CytoView hg38]
Mapping of homologs : NCBIPSMA2 [Mapview hg19]  PSMA2 [Mapview hg38]
OMIM176842   
Gene and transcription
Genbank (Entrez)AK222976 AK290654 AU120930 BC002900 BC047697
RefSeq transcript (Entrez)NM_002787
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMA2
Cluster EST : UnigeneHs.333786 [ NCBI ]
CGAP (NCI)Hs.333786
Alternative Splicing GalleryENSG00000106588
Gene ExpressionPSMA2 [ NCBI-GEO ]   PSMA2 [ EBI - ARRAY_EXPRESS ]   PSMA2 [ SEEK ]   PSMA2 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5683
GTEX Portal (Tissue expression)PSMA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25787   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25787  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25787
Splice isoforms : SwissVarP25787
PhosPhoSitePlusP25787
Domaine pattern : Prosite (Expaxy)PROTEASOME_ALPHA_1 (PS00388)    PROTEASOME_ALPHA_2 (PS51475)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Proteasome_asu_N    Proteasome_suA-type    Proteasome_sua/b   
Domain families : Pfam (Sanger)Proteasome (PF00227)    Proteasome_A_N (PF10584)   
Domain families : Pfam (NCBI)pfam00227    pfam10584   
Domain families : Smart (EMBL)Proteasome_A_N (SM00948)  
Conserved Domain (NCBI)PSMA2
DMDM Disease mutations5683
Blocks (Seattle)PSMA2
PDB (SRS)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (PDBSum)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (IMB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (RSDB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
Structural Biology KnowledgeBase4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SCOP (Structural Classification of Proteins)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
CATH (Classification of proteins structures)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SuperfamilyP25787
Human Protein AtlasENSG00000106588
Peptide AtlasP25787
HPRD08907
IPIIPI00219622   IPI00925799   IPI01009356   IPI00925664   IPI00926198   IPI00927830   
Protein Interaction databases
DIP (DOE-UCLA)P25787
IntAct (EBI)P25787
FunCoupENSG00000106588
BioGRIDPSMA2
STRING (EMBL)PSMA2
ZODIACPSMA2
Ontologies - Pathways
QuickGOP25787
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  P-body  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  extracellular region  nucleus  nucleoplasm  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  response to virus  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  proteasome core complex, alpha-subunit complex  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  secretory granule lumen  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  ficolin-1-rich granule lumen  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  P-body  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  extracellular region  nucleus  nucleoplasm  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  response to virus  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  proteasome core complex, alpha-subunit complex  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  secretory granule lumen  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  ficolin-1-rich granule lumen  
Pathways : KEGGProteasome   
NDEx NetworkPSMA2
Atlas of Cancer Signalling NetworkPSMA2
Wikipedia pathwaysPSMA2
Orthology - Evolution
OrthoDB5683
GeneTree (enSembl)ENSG00000106588
Phylogenetic Trees/Animal Genes : TreeFamPSMA2
HOVERGENP25787
HOGENOMP25787
Homologs : HomoloGenePSMA2
Homology/Alignments : Family Browser (UCSC)PSMA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMA2
dbVarPSMA2
ClinVarPSMA2
1000_GenomesPSMA2 
Exome Variant ServerPSMA2
ExAC (Exome Aggregation Consortium)PSMA2 (select the gene name)
Genetic variants : HAPMAP5683
Genomic Variants (DGV)PSMA2 [DGVbeta]
DECIPHERPSMA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMA2 
Mutations
ICGC Data PortalPSMA2 
TCGA Data PortalPSMA2 
Broad Tumor PortalPSMA2
OASIS PortalPSMA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMA2
DgiDB (Drug Gene Interaction Database)PSMA2
DoCM (Curated mutations)PSMA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMA2 (select a term)
intoGenPSMA2
Cancer3DPSMA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176842   
Orphanet
MedgenPSMA2
Genetic Testing Registry PSMA2
NextProtP25787 [Medical]
TSGene5683
GENETestsPSMA2
Target ValidationPSMA2
Huge Navigator PSMA2 [HugePedia]
snp3D : Map Gene to Disease5683
BioCentury BCIQPSMA2
ClinGenPSMA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5683
Chemical/Pharm GKB GenePA33876
Clinical trialPSMA2
Miscellaneous
canSAR (ICR)PSMA2 (select the gene name)
Probes
Litterature
PubMed120 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMA2
EVEXPSMA2
GoPubMedPSMA2
iHOPPSMA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:26:51 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.