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PSMA5 (proteasome subunit alpha 5)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)ZETA
Other aliasPSC5
HGNC (Hugo) PSMA5
LocusID (NCBI) 5686
Atlas_Id 55417
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 109399031 and ends at 109426448 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KLHL18 (3p21.31) / PSMA5 (1p13.3)NOTCH2 (1p12) / PSMA5 (1p13.3)PSMA5 (1p13.3) / FOXP1 (3p13)
PSMA5 (1p13.3) / USF1 (1q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMA5   9534
Cards
Entrez_Gene (NCBI)PSMA5  5686  proteasome subunit alpha 5
AliasesPSC5; ZETA
GeneCards (Weizmann)PSMA5
Ensembl hg19 (Hinxton)ENSG00000143106 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143106 [Gene_View]  chr1:109399031-109426448 [Contig_View]  PSMA5 [Vega]
ICGC DataPortalENSG00000143106
TCGA cBioPortalPSMA5
AceView (NCBI)PSMA5
Genatlas (Paris)PSMA5
WikiGenes5686
SOURCE (Princeton)PSMA5
Genetics Home Reference (NIH)PSMA5
Genomic and cartography
GoldenPath hg38 (UCSC)PSMA5  -     chr1:109399031-109426448 -  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMA5  -     1p13.3   [Description]    (hg19-Feb_2009)
EnsemblPSMA5 - 1p13.3 [CytoView hg19]  PSMA5 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIPSMA5 [Mapview hg19]  PSMA5 [Mapview hg38]
OMIM176844   
Gene and transcription
Genbank (Entrez)AK124307 AK225990 AK304448 AK313351 BC018605
RefSeq transcript (Entrez)NM_001199772 NM_001199773 NM_001199774 NM_002790
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMA5
Cluster EST : UnigeneHs.485246 [ NCBI ]
CGAP (NCI)Hs.485246
Alternative Splicing GalleryENSG00000143106
Gene ExpressionPSMA5 [ NCBI-GEO ]   PSMA5 [ EBI - ARRAY_EXPRESS ]   PSMA5 [ SEEK ]   PSMA5 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5686
GTEX Portal (Tissue expression)PSMA5
Human Protein AtlasENSG00000143106-PSMA5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28066   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28066  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28066
Splice isoforms : SwissVarP28066
PhosPhoSitePlusP28066
Domaine pattern : Prosite (Expaxy)PROTEASOME_ALPHA_1 (PS00388)    PROTEASOME_ALPHA_2 (PS51475)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Proteasome_alpha_type_5    Proteasome_asu_N    Proteasome_suA-type    Proteasome_sua/b   
Domain families : Pfam (Sanger)Proteasome (PF00227)    Proteasome_A_N (PF10584)   
Domain families : Pfam (NCBI)pfam00227    pfam10584   
Domain families : Smart (EMBL)Proteasome_A_N (SM00948)  
Conserved Domain (NCBI)PSMA5
DMDM Disease mutations5686
Blocks (Seattle)PSMA5
PDB (SRS)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (PDBSum)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (IMB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (RSDB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
Structural Biology KnowledgeBase4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SCOP (Structural Classification of Proteins)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
CATH (Classification of proteins structures)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SuperfamilyP28066
Human Protein Atlas [tissue]ENSG00000143106-PSMA5 [tissue]
Peptide AtlasP28066
HPRD01464
IPIIPI00291922   IPI00983632   
Protein Interaction databases
DIP (DOE-UCLA)P28066
IntAct (EBI)P28066
FunCoupENSG00000143106
BioGRIDPSMA5
STRING (EMBL)PSMA5
ZODIACPSMA5
Ontologies - Pathways
QuickGOP28066
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  extracellular region  nucleus  nucleoplasm  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  proteasome core complex, alpha-subunit complex  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  secretory granule lumen  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  ficolin-1-rich granule lumen  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  extracellular region  nucleus  nucleoplasm  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  proteasome core complex, alpha-subunit complex  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  secretory granule lumen  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  ficolin-1-rich granule lumen  
Pathways : KEGGProteasome   
NDEx NetworkPSMA5
Atlas of Cancer Signalling NetworkPSMA5
Wikipedia pathwaysPSMA5
Orthology - Evolution
OrthoDB5686
GeneTree (enSembl)ENSG00000143106
Phylogenetic Trees/Animal Genes : TreeFamPSMA5
HOVERGENP28066
HOGENOMP28066
Homologs : HomoloGenePSMA5
Homology/Alignments : Family Browser (UCSC)PSMA5
Gene fusions - Rearrangements
Tumor Fusion PortalPSMA5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMA5
dbVarPSMA5
ClinVarPSMA5
1000_GenomesPSMA5 
Exome Variant ServerPSMA5
ExAC (Exome Aggregation Consortium)ENSG00000143106
GNOMAD BrowserENSG00000143106
Genetic variants : HAPMAP5686
Genomic Variants (DGV)PSMA5 [DGVbeta]
DECIPHERPSMA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMA5 
Mutations
ICGC Data PortalPSMA5 
TCGA Data PortalPSMA5 
Broad Tumor PortalPSMA5
OASIS PortalPSMA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMA5
DgiDB (Drug Gene Interaction Database)PSMA5
DoCM (Curated mutations)PSMA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMA5 (select a term)
intoGenPSMA5
Cancer3DPSMA5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176844   
Orphanet
DisGeNETPSMA5
MedgenPSMA5
Genetic Testing Registry PSMA5
NextProtP28066 [Medical]
TSGene5686
GENETestsPSMA5
Target ValidationPSMA5
Huge Navigator PSMA5 [HugePedia]
snp3D : Map Gene to Disease5686
BioCentury BCIQPSMA5
ClinGenPSMA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5686
Chemical/Pharm GKB GenePA33879
Clinical trialPSMA5
Miscellaneous
canSAR (ICR)PSMA5 (select the gene name)
Probes
Litterature
PubMed113 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMA5
EVEXPSMA5
GoPubMedPSMA5
iHOPPSMA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:54:18 CET 2017

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