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PSMA7 (proteasome subunit alpha 7)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)XAPC7
C6
HSPC
RC6-1
Other aliasHEL-S-276
HGNC (Hugo) PSMA7
LocusID (NCBI) 5688
Atlas_Id 50091
Location 20q13.33  [Link to chromosome band 20q13]
Location_base_pair Starts at 60711783 and ends at 60718514 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABCC5 (3q27.1) / PSMA7 (20q13.33)NCL (2q37.1) / PSMA7 (20q13.33)PA2G4 (12q13.2) / PSMA7 (20q13.33)
PSMA7 (20q13.33) / PSMA7 (20q13.33)PSMA7 (20q13.33) / RBBP7 (Xp22.2)PSMA7 (20q13.33) / UBA52 (19p13.11)
RPS6KL1 (14q24.3) / PSMA7 (20q13.33)TAF4 (20q13.33) / PSMA7 (20q13.33)TESC (12q24.22) / PSMA7 (20q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMA7   9536
Cards
Entrez_Gene (NCBI)PSMA7  5688  proteasome subunit alpha 7
AliasesC6; HEL-S-276; HSPC; RC6-1; 
XAPC7
GeneCards (Weizmann)PSMA7
Ensembl hg19 (Hinxton)ENSG00000101182 [Gene_View]  chr20:60711783-60718514 [Contig_View]  PSMA7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101182 [Gene_View]  chr20:60711783-60718514 [Contig_View]  PSMA7 [Vega]
ICGC DataPortalENSG00000101182
TCGA cBioPortalPSMA7
AceView (NCBI)PSMA7
Genatlas (Paris)PSMA7
WikiGenes5688
SOURCE (Princeton)PSMA7
Genetics Home Reference (NIH)PSMA7
Genomic and cartography
GoldenPath hg19 (UCSC)PSMA7  -     chr20:60711783-60718514 -  20q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PSMA7  -     20q13.33   [Description]    (hg38-Dec_2013)
EnsemblPSMA7 - 20q13.33 [CytoView hg19]  PSMA7 - 20q13.33 [CytoView hg38]
Mapping of homologs : NCBIPSMA7 [Mapview hg19]  PSMA7 [Mapview hg38]
OMIM606607   
Gene and transcription
Genbank (Entrez)AF022815 AF054185 AK127210 AK312025 BC001895
RefSeq transcript (Entrez)NM_002792 NM_152255
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011362 NW_004929418
Consensus coding sequences : CCDS (NCBI)PSMA7
Cluster EST : UnigeneHs.233952 [ NCBI ]
CGAP (NCI)Hs.233952
Alternative Splicing GalleryENSG00000101182
Gene ExpressionPSMA7 [ NCBI-GEO ]   PSMA7 [ EBI - ARRAY_EXPRESS ]   PSMA7 [ SEEK ]   PSMA7 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMA7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5688
GTEX Portal (Tissue expression)PSMA7
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14818   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14818  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14818
Splice isoforms : SwissVarO14818
Catalytic activity : Enzyme3.4.25.1 [ Enzyme-Expasy ]   3.4.25.13.4.25.1 [ IntEnz-EBI ]   3.4.25.1 [ BRENDA ]   3.4.25.1 [ KEGG ]   
PhosPhoSitePlusO14818
Domaine pattern : Prosite (Expaxy)PROTEASOME_ALPHA_1 (PS00388)    PROTEASOME_ALPHA_2 (PS51475)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Proteasome_asu_N    Proteasome_suA-type    Proteasome_sua/b   
Domain families : Pfam (Sanger)Proteasome (PF00227)    Proteasome_A_N (PF10584)   
Domain families : Pfam (NCBI)pfam00227    pfam10584   
Domain families : Smart (EMBL)Proteasome_A_N (SM00948)  
Conserved Domain (NCBI)PSMA7
DMDM Disease mutations5688
Blocks (Seattle)PSMA7
PDB (SRS)4R3O    4R67    5A0Q   
PDB (PDBSum)4R3O    4R67    5A0Q   
PDB (IMB)4R3O    4R67    5A0Q   
PDB (RSDB)4R3O    4R67    5A0Q   
Structural Biology KnowledgeBase4R3O    4R67    5A0Q   
SCOP (Structural Classification of Proteins)4R3O    4R67    5A0Q   
CATH (Classification of proteins structures)4R3O    4R67    5A0Q   
SuperfamilyO14818
Human Protein AtlasENSG00000101182
Peptide AtlasO14818
HPRD05967
IPIIPI00024175   IPI00218372   IPI00847750   IPI00647380   
Protein Interaction databases
DIP (DOE-UCLA)O14818
IntAct (EBI)O14818
FunCoupENSG00000101182
BioGRIDPSMA7
STRING (EMBL)PSMA7
ZODIACPSMA7
Ontologies - Pathways
QuickGOO14818
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  nucleus  nucleoplasm  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  viral process  proteasome core complex, alpha-subunit complex  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  identical protein binding  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  Wnt signaling pathway, planar cell polarity pathway  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  nucleus  nucleoplasm  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  viral process  proteasome core complex, alpha-subunit complex  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  identical protein binding  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  Wnt signaling pathway, planar cell polarity pathway  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Pathways : BIOCARTAY branching of actin filaments [Genes]   
Pathways : KEGGProteasome   
NDEx NetworkPSMA7
Atlas of Cancer Signalling NetworkPSMA7
Wikipedia pathwaysPSMA7
Orthology - Evolution
OrthoDB5688
GeneTree (enSembl)ENSG00000101182
Phylogenetic Trees/Animal Genes : TreeFamPSMA7
HOVERGENO14818
HOGENOMO14818
Homologs : HomoloGenePSMA7
Homology/Alignments : Family Browser (UCSC)PSMA7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMA7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMA7
dbVarPSMA7
ClinVarPSMA7
1000_GenomesPSMA7 
Exome Variant ServerPSMA7
ExAC (Exome Aggregation Consortium)PSMA7 (select the gene name)
Genetic variants : HAPMAP5688
Genomic Variants (DGV)PSMA7 [DGVbeta]
DECIPHER (Syndromes)20:60711783-60718514  ENSG00000101182
CONAN: Copy Number AnalysisPSMA7 
Mutations
ICGC Data PortalPSMA7 
TCGA Data PortalPSMA7 
Broad Tumor PortalPSMA7
OASIS PortalPSMA7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMA7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMA7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMA7
DgiDB (Drug Gene Interaction Database)PSMA7
DoCM (Curated mutations)PSMA7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMA7 (select a term)
intoGenPSMA7
Cancer3DPSMA7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606607   
Orphanet
MedgenPSMA7
Genetic Testing Registry PSMA7
NextProtO14818 [Medical]
TSGene5688
GENETestsPSMA7
Huge Navigator PSMA7 [HugePedia]
snp3D : Map Gene to Disease5688
BioCentury BCIQPSMA7
ClinGenPSMA7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5688
Chemical/Pharm GKB GenePA33881
Clinical trialPSMA7
Miscellaneous
canSAR (ICR)PSMA7 (select the gene name)
Probes
Litterature
PubMed138 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMA7
EVEXPSMA7
GoPubMedPSMA7
iHOPPSMA7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:23:18 CET 2017

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