Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PSMB1 (proteasome subunit beta 1)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)PMSB1
HC5
Other aliasPSC5
HGNC (Hugo) PSMB1
LocusID (NCBI) 5689
Atlas_Id 51669
Location 6q27  [Link to chromosome band 6q27]
Location_base_pair Starts at 170535116 and ends at 170553329 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ATP8A1 (4p13) / PSMB1 (6q27)BCLAF1 (6q23.3) / PSMB1 (6q27)CDYL2 (16q23.2) / PSMB1 (6q27)
GSTP1 (11q13.2) / PSMB1 (6q27)PDE10A (6q27) / PSMB1 (6q27)PSMB1 (6q27) / GPBP1 (5q11.2)
YBX3 (12p13.2) / PSMB1 (6q27)ZFAND6 (15q25.1) / PSMB1 (6q27)PDE10A 6q27 / PSMB1 6q27

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMB1   9537
Cards
Entrez_Gene (NCBI)PSMB1  5689  proteasome subunit beta 1
AliasesHC5; PMSB1; PSC5
GeneCards (Weizmann)PSMB1
Ensembl hg19 (Hinxton)ENSG00000008018 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000008018 [Gene_View]  ENSG00000008018 [Sequence]  chr6:170535116-170553329 [Contig_View]  PSMB1 [Vega]
ICGC DataPortalENSG00000008018
TCGA cBioPortalPSMB1
AceView (NCBI)PSMB1
Genatlas (Paris)PSMB1
WikiGenes5689
SOURCE (Princeton)PSMB1
Genetics Home Reference (NIH)PSMB1
Genomic and cartography
GoldenPath hg38 (UCSC)PSMB1  -     chr6:170535116-170553329 -  6q27   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMB1  -     6q27   [Description]    (hg19-Feb_2009)
EnsemblPSMB1 - 6q27 [CytoView hg19]  PSMB1 - 6q27 [CytoView hg38]
Mapping of homologs : NCBIPSMB1 [Mapview hg19]  PSMB1 [Mapview hg38]
OMIM602017   
Gene and transcription
Genbank (Entrez)AB209078 AB451312 AB451442 AK023290 AK058050
RefSeq transcript (Entrez)NM_002793
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMB1
Cluster EST : UnigeneHs.352768 [ NCBI ]
CGAP (NCI)Hs.352768
Alternative Splicing GalleryENSG00000008018
Gene ExpressionPSMB1 [ NCBI-GEO ]   PSMB1 [ EBI - ARRAY_EXPRESS ]   PSMB1 [ SEEK ]   PSMB1 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5689
GTEX Portal (Tissue expression)PSMB1
Human Protein AtlasENSG00000008018-PSMB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20618   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20618  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20618
Splice isoforms : SwissVarP20618
PhosPhoSitePlusP20618
Domaine pattern : Prosite (Expaxy)PROTEASOME_BETA_1 (PS00854)    PROTEASOME_BETA_2 (PS51476)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Proteasome_beta1    Proteasome_bsu_CS    Proteasome_sua/b    Proteasome_suB-type   
Domain families : Pfam (Sanger)Proteasome (PF00227)   
Domain families : Pfam (NCBI)pfam00227   
Conserved Domain (NCBI)PSMB1
DMDM Disease mutations5689
Blocks (Seattle)PSMB1
PDB (SRS)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
PDB (PDBSum)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
PDB (IMB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
PDB (RSDB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
Structural Biology KnowledgeBase4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
SCOP (Structural Classification of Proteins)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
CATH (Classification of proteins structures)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5B    5L5D    5L5E    5L5F    5L5H    5L5I    5L5J    5L5O    5L5P    5L5Q    5L5R    5L5S    5L5T    5L5U    5L5V    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5LN3    5M2B    5M32    5T0C    5T0G    5T0H    5T0I    5T0J    6AVO   
SuperfamilyP20618
Human Protein Atlas [tissue]ENSG00000008018-PSMB1 [tissue]
Peptide AtlasP20618
HPRD03603
IPIIPI00025019   IPI00556291   
Protein Interaction databases
DIP (DOE-UCLA)P20618
IntAct (EBI)P20618
FunCoupENSG00000008018
BioGRIDPSMB1
STRING (EMBL)PSMB1
ZODIACPSMB1
Ontologies - Pathways
QuickGOP20618
Ontology : AmiGOproteasome complex  endopeptidase activity  threonine-type endopeptidase activity  protein binding  extracellular region  nucleus  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  proteasome core complex  proteasome core complex  proteasomal protein catabolic process  proteasomal ubiquitin-independent protein catabolic process  viral process  protein deubiquitination  proteasome core complex, beta-subunit complex  secretory granule lumen  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  post-translational protein modification  extracellular exosome  ficolin-1-rich granule lumen  
Ontology : EGO-EBIproteasome complex  endopeptidase activity  threonine-type endopeptidase activity  protein binding  extracellular region  nucleus  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  proteasome core complex  proteasome core complex  proteasomal protein catabolic process  proteasomal ubiquitin-independent protein catabolic process  viral process  protein deubiquitination  proteasome core complex, beta-subunit complex  secretory granule lumen  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  post-translational protein modification  extracellular exosome  ficolin-1-rich granule lumen  
Pathways : KEGGProteasome   
NDEx NetworkPSMB1
Atlas of Cancer Signalling NetworkPSMB1
Wikipedia pathwaysPSMB1
Orthology - Evolution
OrthoDB5689
GeneTree (enSembl)ENSG00000008018
Phylogenetic Trees/Animal Genes : TreeFamPSMB1
HOVERGENP20618
HOGENOMP20618
Homologs : HomoloGenePSMB1
Homology/Alignments : Family Browser (UCSC)PSMB1
Gene fusions - Rearrangements
Fusion PortalPDE10A 6q27 PSMB1 6q27 BRCA
Fusion : QuiverPSMB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMB1
dbVarPSMB1
ClinVarPSMB1
1000_GenomesPSMB1 
Exome Variant ServerPSMB1
ExAC (Exome Aggregation Consortium)ENSG00000008018
GNOMAD BrowserENSG00000008018
Varsome BrowserPSMB1
Genetic variants : HAPMAP5689
Genomic Variants (DGV)PSMB1 [DGVbeta]
DECIPHERPSMB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMB1 
Mutations
ICGC Data PortalPSMB1 
TCGA Data PortalPSMB1 
Broad Tumor PortalPSMB1
OASIS PortalPSMB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMB1
DgiDB (Drug Gene Interaction Database)PSMB1
DoCM (Curated mutations)PSMB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMB1 (select a term)
intoGenPSMB1
Cancer3DPSMB1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602017   
Orphanet
DisGeNETPSMB1
MedgenPSMB1
Genetic Testing Registry PSMB1
NextProtP20618 [Medical]
TSGene5689
GENETestsPSMB1
Target ValidationPSMB1
Huge Navigator PSMB1 [HugePedia]
snp3D : Map Gene to Disease5689
BioCentury BCIQPSMB1
ClinGenPSMB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5689
Chemical/Pharm GKB GenePA33882
Clinical trialPSMB1
Miscellaneous
canSAR (ICR)PSMB1 (select the gene name)
Probes
Litterature
PubMed123 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMB1
EVEXPSMB1
GoPubMedPSMB1
iHOPPSMB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:32:51 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.