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PSMB11 (proteasome subunit beta 11)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)beta5t
Other aliasBETA5T
HGNC (Hugo) PSMB11
LocusID (NCBI) 122706
Atlas_Id 52407
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 23042167 and ends at 23044060 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMB11   31963
Cards
Entrez_Gene (NCBI)PSMB11  122706  proteasome subunit beta 11
AliasesBETA5T
GeneCards (Weizmann)PSMB11
Ensembl hg19 (Hinxton)ENSG00000222028 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000222028 [Gene_View]  chr14:23042167-23044060 [Contig_View]  PSMB11 [Vega]
ICGC DataPortalENSG00000222028
TCGA cBioPortalPSMB11
AceView (NCBI)PSMB11
Genatlas (Paris)PSMB11
WikiGenes122706
SOURCE (Princeton)PSMB11
Genetics Home Reference (NIH)PSMB11
Genomic and cartography
GoldenPath hg38 (UCSC)PSMB11  -     chr14:23042167-23044060 +  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMB11  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblPSMB11 - 14q11.2 [CytoView hg19]  PSMB11 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIPSMB11 [Mapview hg19]  PSMB11 [Mapview hg38]
OMIM611137   
Gene and transcription
Genbank (Entrez)AB299437 AK122797
RefSeq transcript (Entrez)NM_001099780
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMB11
Cluster EST : UnigeneHs.508918 [ NCBI ]
CGAP (NCI)Hs.508918
Alternative Splicing GalleryENSG00000222028
Gene ExpressionPSMB11 [ NCBI-GEO ]   PSMB11 [ EBI - ARRAY_EXPRESS ]   PSMB11 [ SEEK ]   PSMB11 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMB11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)122706
GTEX Portal (Tissue expression)PSMB11
Protein : pattern, domain, 3D structure
UniProt/SwissProtA5LHX3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA5LHX3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA5LHX3
Splice isoforms : SwissVarA5LHX3
Catalytic activity : Enzyme3.4.25.1 [ Enzyme-Expasy ]   3.4.25.13.4.25.1 [ IntEnz-EBI ]   3.4.25.1 [ BRENDA ]   3.4.25.1 [ KEGG ]   
PhosPhoSitePlusA5LHX3
Domaine pattern : Prosite (Expaxy)PROTEASOME_BETA_1 (PS00854)    PROTEASOME_BETA_2 (PS51476)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Pept_T1A_subB    Proteasome_bsu_CS    Proteasome_sua/b    Proteasome_suB-type   
Domain families : Pfam (Sanger)Proteasome (PF00227)   
Domain families : Pfam (NCBI)pfam00227   
Conserved Domain (NCBI)PSMB11
DMDM Disease mutations122706
Blocks (Seattle)PSMB11
SuperfamilyA5LHX3
Human Protein AtlasENSG00000222028
Peptide AtlasA5LHX3
IPIIPI00051808   
Protein Interaction databases
DIP (DOE-UCLA)A5LHX3
IntAct (EBI)A5LHX3
FunCoupENSG00000222028
BioGRIDPSMB11
STRING (EMBL)PSMB11
ZODIACPSMB11
Ontologies - Pathways
QuickGOA5LHX3
Ontology : AmiGOMAPK cascade  protein polyubiquitination  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  nucleus  cytosol  proteasome core complex  proteolysis  regulation of cellular amino acid metabolic process  peptidase activity  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  CD8-positive, alpha-beta T cell differentiation  regulation of mRNA stability  T cell receptor signaling pathway  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  nucleus  cytosol  proteasome core complex  proteolysis  regulation of cellular amino acid metabolic process  peptidase activity  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  CD8-positive, alpha-beta T cell differentiation  regulation of mRNA stability  T cell receptor signaling pathway  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Pathways : KEGGProteasome   
NDEx NetworkPSMB11
Atlas of Cancer Signalling NetworkPSMB11
Wikipedia pathwaysPSMB11
Orthology - Evolution
OrthoDB122706
GeneTree (enSembl)ENSG00000222028
Phylogenetic Trees/Animal Genes : TreeFamPSMB11
HOVERGENA5LHX3
HOGENOMA5LHX3
Homologs : HomoloGenePSMB11
Homology/Alignments : Family Browser (UCSC)PSMB11
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMB11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMB11
dbVarPSMB11
ClinVarPSMB11
1000_GenomesPSMB11 
Exome Variant ServerPSMB11
ExAC (Exome Aggregation Consortium)PSMB11 (select the gene name)
Genetic variants : HAPMAP122706
Genomic Variants (DGV)PSMB11 [DGVbeta]
DECIPHERPSMB11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMB11 
Mutations
ICGC Data PortalPSMB11 
TCGA Data PortalPSMB11 
Broad Tumor PortalPSMB11
OASIS PortalPSMB11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMB11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMB11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMB11
DgiDB (Drug Gene Interaction Database)PSMB11
DoCM (Curated mutations)PSMB11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMB11 (select a term)
intoGenPSMB11
Cancer3DPSMB11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611137   
Orphanet
MedgenPSMB11
Genetic Testing Registry PSMB11
NextProtA5LHX3 [Medical]
TSGene122706
GENETestsPSMB11
Target ValidationPSMB11
Huge Navigator PSMB11 [HugePedia]
snp3D : Map Gene to Disease122706
BioCentury BCIQPSMB11
ClinGenPSMB11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD122706
Chemical/Pharm GKB GenePA162400222
Clinical trialPSMB11
Miscellaneous
canSAR (ICR)PSMB11 (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMB11
EVEXPSMB11
GoPubMedPSMB11
iHOPPSMB11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:11:54 CEST 2017

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