Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PSMB5 (proteasome subunit beta 5)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)X
MB1
Other aliasLMPX
HGNC (Hugo) PSMB5
LocusID (NCBI) 5693
Atlas_Id 54051
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 23025851 and ends at 23035220 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PSMB5 (14q11.2) / PSMB5 (14q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMB5   9542
Cards
Entrez_Gene (NCBI)PSMB5  5693  proteasome subunit beta 5
AliasesLMPX; MB1; X
GeneCards (Weizmann)PSMB5
Ensembl hg19 (Hinxton)ENSG00000100804 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100804 [Gene_View]  chr14:23025851-23035220 [Contig_View]  PSMB5 [Vega]
ICGC DataPortalENSG00000100804
TCGA cBioPortalPSMB5
AceView (NCBI)PSMB5
Genatlas (Paris)PSMB5
WikiGenes5693
SOURCE (Princeton)PSMB5
Genetics Home Reference (NIH)PSMB5
Genomic and cartography
GoldenPath hg38 (UCSC)PSMB5  -     chr14:23025851-23035220 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMB5  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblPSMB5 - 14q11.2 [CytoView hg19]  PSMB5 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIPSMB5 [Mapview hg19]  PSMB5 [Mapview hg38]
OMIM600306   
Gene and transcription
Genbank (Entrez)AK225888 AK300714 AK311895 BC057840 BC107720
RefSeq transcript (Entrez)NM_001130725 NM_001144932 NM_002797
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMB5
Cluster EST : UnigeneHs.422990 [ NCBI ]
CGAP (NCI)Hs.422990
Alternative Splicing GalleryENSG00000100804
Gene ExpressionPSMB5 [ NCBI-GEO ]   PSMB5 [ EBI - ARRAY_EXPRESS ]   PSMB5 [ SEEK ]   PSMB5 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMB5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5693
GTEX Portal (Tissue expression)PSMB5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28074   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28074  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28074
Splice isoforms : SwissVarP28074
PhosPhoSitePlusP28074
Domaine pattern : Prosite (Expaxy)PROTEASOME_BETA_1 (PS00854)    PROTEASOME_BETA_2 (PS51476)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Pept_T1A_subB    Proteasome_bsu_CS    Proteasome_sua/b    Proteasome_suB-type   
Domain families : Pfam (Sanger)Proteasome (PF00227)   
Domain families : Pfam (NCBI)pfam00227   
Conserved Domain (NCBI)PSMB5
DMDM Disease mutations5693
Blocks (Seattle)PSMB5
PDB (SRS)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (PDBSum)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (IMB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (RSDB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
Structural Biology KnowledgeBase4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SCOP (Structural Classification of Proteins)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
CATH (Classification of proteins structures)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5L5W    5L5X    5L5Y    5L5Z    5L60    5L61    5L62    5L63    5L64    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SuperfamilyP28074
Human Protein AtlasENSG00000100804
Peptide AtlasP28074
HPRD02629
IPIIPI00479306   IPI00383971   IPI01024783   IPI01026557   IPI01026274   IPI00910237   
Protein Interaction databases
DIP (DOE-UCLA)P28074
IntAct (EBI)P28074
FunCoupENSG00000100804
BioGRIDPSMB5
STRING (EMBL)PSMB5
ZODIACPSMB5
Ontologies - Pathways
QuickGOP28074
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  centrosome  cytosol  proteasome core complex  proteolysis  regulation of cellular amino acid metabolic process  response to oxidative stress  peptidase activity  negative regulation of G2/M transition of mitotic cell cycle  viral process  protein deubiquitination  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  threonine-type endopeptidase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  centrosome  cytosol  proteasome core complex  proteolysis  regulation of cellular amino acid metabolic process  response to oxidative stress  peptidase activity  negative regulation of G2/M transition of mitotic cell cycle  viral process  protein deubiquitination  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Pathways : BIOCARTAAntigen Processing and Presentation [Genes]   
Pathways : KEGGProteasome   
NDEx NetworkPSMB5
Atlas of Cancer Signalling NetworkPSMB5
Wikipedia pathwaysPSMB5
Orthology - Evolution
OrthoDB5693
GeneTree (enSembl)ENSG00000100804
Phylogenetic Trees/Animal Genes : TreeFamPSMB5
HOVERGENP28074
HOGENOMP28074
Homologs : HomoloGenePSMB5
Homology/Alignments : Family Browser (UCSC)PSMB5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMB5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMB5
dbVarPSMB5
ClinVarPSMB5
1000_GenomesPSMB5 
Exome Variant ServerPSMB5
ExAC (Exome Aggregation Consortium)PSMB5 (select the gene name)
Genetic variants : HAPMAP5693
Genomic Variants (DGV)PSMB5 [DGVbeta]
DECIPHERPSMB5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMB5 
Mutations
ICGC Data PortalPSMB5 
TCGA Data PortalPSMB5 
Broad Tumor PortalPSMB5
OASIS PortalPSMB5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMB5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMB5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMB5
DgiDB (Drug Gene Interaction Database)PSMB5
DoCM (Curated mutations)PSMB5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMB5 (select a term)
intoGenPSMB5
Cancer3DPSMB5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600306   
Orphanet
MedgenPSMB5
Genetic Testing Registry PSMB5
NextProtP28074 [Medical]
TSGene5693
GENETestsPSMB5
Target ValidationPSMB5
Huge Navigator PSMB5 [HugePedia]
snp3D : Map Gene to Disease5693
BioCentury BCIQPSMB5
ClinGenPSMB5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5693
Chemical/Pharm GKB GenePA33887
Clinical trialPSMB5
Miscellaneous
canSAR (ICR)PSMB5 (select the gene name)
Probes
Litterature
PubMed126 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMB5
EVEXPSMB5
GoPubMedPSMB5
iHOPPSMB5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:26:54 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.