| Nomenclature |
|---|
| HGNC (Hugo) | PSMB6 9543 |
| Cards |
|---|
| Entrez_Gene (NCBI) | PSMB6 proteasome 20S subunit beta 6 |
| Aliases | DELTA; LMPY; Y |
| GeneCards (Weizmann) | PSMB6 |
| Ensembl hg19 (Hinxton) | ENSG00000142507 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000142507 [Gene_View] ENSG00000142507 [Sequence] chr17:4796164-4798495 [Contig_View] PSMB6 [Vega] |
| ICGC DataPortal | ENSG00000142507 |
| TCGA cBioPortal | PSMB6 |
| AceView (NCBI) | PSMB6 |
| Genatlas (Paris) | PSMB6 |
| SOURCE (Princeton) | PSMB6 |
| Genetics Home Reference (NIH) | PSMB6 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | PSMB6 - chr17:4796164-4798495 + 17p13.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | PSMB6 - 17p13.2 [Description] (hg19-Feb_2009) |
| GoldenPath | PSMB6 - 17p13.2 [CytoView hg19] PSMB6 - 17p13.2 [CytoView hg38] |
| ImmunoBase | ENSG00000142507 |
| genome Data Viewer NCBI | PSMB6 [Mapview hg19] |
| OMIM | 600307 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK311768 BC000835 BF671774 BM553399 BQ691763 |
| RefSeq transcript (Entrez) | NM_001270481 NM_002798 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | PSMB6 |
| Alternative Splicing Gallery | ENSG00000142507 |
| Gene Expression | PSMB6 [ NCBI-GEO ] PSMB6 [ EBI - ARRAY_EXPRESS ]
PSMB6 [ SEEK ] PSMB6 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | PSMB6 [ Firebrowse - Broad ] |
| Genevisible | Expression of PSMB6 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5694 |
| GTEX Portal (Tissue expression) | PSMB6 |
| Human Protein Atlas | ENSG00000142507-PSMB6 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P28072 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P28072 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P28072 |
| Splice isoforms : SwissVar | P28072 |
| PhosPhoSitePlus | P28072 |
| Domaine pattern : Prosite (Expaxy) | PROTEASOME_BETA_1 (PS00854) PROTEASOME_BETA_2 (PS51476) |
| Domains : Interpro (EBI) | Ntn_hydrolases_N Pept_T1A_subB Proteasome_beta6 Proteasome_bsu_CS Proteasome_sua/b Proteasome_suB-type |
| Domain families : Pfam (Sanger) | Proteasome (PF00227) |
| Domain families : Pfam (NCBI) | pfam00227 |
| Conserved Domain (NCBI) | PSMB6 |
| Blocks (Seattle) | PSMB6 |
| PDB (RSDB) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| PDB Europe | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| PDB (PDBSum) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| PDB (IMB) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| Structural Biology KnowledgeBase | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| SCOP (Structural Classification of Proteins) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| CATH (Classification of proteins structures) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFO 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6R70 6REY 6RGQ |
| Superfamily | P28072 |
| Human Protein Atlas [tissue] | ENSG00000142507-PSMB6 [tissue] |
| Peptide Atlas | P28072 |
| HPRD | 02630 |
| IPI | IPI00000811 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P28072 |
| IntAct (EBI) | P28072 |
| BioGRID | PSMB6 |
| STRING (EMBL) | PSMB6 |
| ZODIAC | PSMB6 |
| Ontologies - Pathways |
|---|
| QuickGO | P28072 |
| Ontology : AmiGO | MAPK cascade protein polyubiquitination proteasome complex stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent endopeptidase activity endopeptidase activity threonine-type endopeptidase activity protein binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol proteasome core complex proteasome core complex regulation of cellular amino acid metabolic process proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process negative regulation of G2/M transition of mitotic cell cycle viral process protein deubiquitination proteasome core complex, beta-subunit complex anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability post-translational protein modification cadherin binding T cell receptor signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia extracellular exosome interleukin-1-mediated signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway regulation of mitotic cell cycle phase transition regulation of hematopoietic stem cell differentiation |
| Ontology : EGO-EBI | MAPK cascade protein polyubiquitination proteasome complex stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent endopeptidase activity endopeptidase activity threonine-type endopeptidase activity protein binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol proteasome core complex proteasome core complex regulation of cellular amino acid metabolic process proteasomal protein catabolic process proteasomal ubiquitin-independent protein catabolic process negative regulation of G2/M transition of mitotic cell cycle viral process protein deubiquitination proteasome core complex, beta-subunit complex anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability post-translational protein modification cadherin binding T cell receptor signaling pathway transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia extracellular exosome interleukin-1-mediated signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway regulation of mitotic cell cycle phase transition regulation of hematopoietic stem cell differentiation |
| Pathways : KEGG | Proteasome |
| NDEx Network | PSMB6 |
| Atlas of Cancer Signalling Network | PSMB6 |
| Wikipedia pathways | PSMB6 |
| Orthology - Evolution |
|---|
| OrthoDB | 5694 |
| GeneTree (enSembl) | ENSG00000142507 |
| Phylogenetic Trees/Animal Genes : TreeFam | PSMB6 |
| HOGENOM | P28072 |
| Homologs : HomoloGene | PSMB6 |
| Homology/Alignments : Family Browser (UCSC) | PSMB6 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | PSMB6 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | PSMB6 [hg38] |
| dbVar | PSMB6 |
| ClinVar | PSMB6 |
| Monarch | PSMB6 |
| 1000_Genomes | PSMB6 |
| Exome Variant Server | PSMB6 |
| GNOMAD Browser | ENSG00000142507 |
| Varsome Browser | PSMB6 |
| Genomic Variants (DGV) | PSMB6 [DGVbeta] |
| DECIPHER | PSMB6 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | PSMB6 |
| Mutations |
|---|
| ICGC Data Portal | PSMB6 |
| TCGA Data Portal | PSMB6 |
| Broad Tumor Portal | PSMB6 |
| OASIS Portal | PSMB6 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | PSMB6 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | PSMB6 |
| Mutations and Diseases : HGMD | PSMB6 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search PSMB6 |
| DgiDB (Drug Gene Interaction Database) | PSMB6 |
| DoCM (Curated mutations) | PSMB6 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | PSMB6 (select a term) |
| intoGen | PSMB6 |
| Cancer3D | PSMB6(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600307 |
| Orphanet | |
| DisGeNET | PSMB6 |
| Medgen | PSMB6 |
| Genetic Testing Registry | PSMB6
|
| NextProt | P28072 [Medical] |
| GENETests | PSMB6 |
| Target Validation | PSMB6 |
| Huge Navigator |
PSMB6 [HugePedia] |
| ClinGen | PSMB6 |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | PSMB6 |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA33888 |
| Pharos | P28072 |
| Clinical trial | PSMB6 |
| Miscellaneous |
|---|
| canSAR (ICR) | PSMB6 (select the gene name) |
| Harmonizome | PSMB6 |
| DataMed Index | PSMB6 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 123 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | PSMB6 |
