| Nomenclature |
|---|
| HGNC (Hugo) | PSMB6 9543 |
| Cards |
|---|
| Entrez_Gene (NCBI) | PSMB6 5694 proteasome subunit beta 6 |
| Aliases | DELTA; LMPY; Y |
| GeneCards (Weizmann) | PSMB6 |
| Ensembl hg19 (Hinxton) | ENSG00000142507 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000142507 [Gene_View] ENSG00000142507 [Sequence] chr17:4796144-4798503 [Contig_View] PSMB6 [Vega] |
| ICGC DataPortal | ENSG00000142507 |
| TCGA cBioPortal | PSMB6 |
| AceView (NCBI) | PSMB6 |
| Genatlas (Paris) | PSMB6 |
| WikiGenes | 5694 |
| SOURCE (Princeton) | PSMB6 |
| Genetics Home Reference (NIH) | PSMB6 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | PSMB6 - chr17:4796144-4798503 + 17p13.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | PSMB6 - 17p13.2 [Description] (hg19-Feb_2009) |
| Ensembl | PSMB6 - 17p13.2 [CytoView hg19] PSMB6 - 17p13.2 [CytoView hg38] |
| Mapping of homologs : NCBI | PSMB6 [Mapview hg19] PSMB6 [Mapview hg38] |
| OMIM | 600307 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AK311768 BC000835 BF671774 BM553399 BQ691763 |
| RefSeq transcript (Entrez) | NM_001270481 NM_002798 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | PSMB6 |
| Cluster EST : Unigene | Hs.77060 [ NCBI ] |
| CGAP (NCI) | Hs.77060 |
| Alternative Splicing Gallery | ENSG00000142507 |
| Gene Expression | PSMB6 [ NCBI-GEO ] PSMB6 [ EBI - ARRAY_EXPRESS ]
PSMB6 [ SEEK ] PSMB6 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | PSMB6 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 5694 |
| GTEX Portal (Tissue expression) | PSMB6 |
| Human Protein Atlas | ENSG00000142507-PSMB6 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P28072 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P28072 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P28072 |
| Splice isoforms : SwissVar | P28072 |
| PhosPhoSitePlus | P28072 |
| Domaine pattern : Prosite (Expaxy) | PROTEASOME_BETA_1 (PS00854) PROTEASOME_BETA_2 (PS51476) |
| Domains : Interpro (EBI) | Ntn_hydrolases_N Pept_T1A_subB Proteasome_bsu_CS Proteasome_sua/b Proteasome_suB-type |
| Domain families : Pfam (Sanger) | Proteasome (PF00227) |
| Domain families : Pfam (NCBI) | pfam00227 |
| Conserved Domain (NCBI) | PSMB6 |
| DMDM Disease mutations | 5694 |
| Blocks (Seattle) | PSMB6 |
| PDB (SRS) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| PDB (PDBSum) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| PDB (IMB) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| PDB (RSDB) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| Structural Biology KnowledgeBase | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| SCOP (Structural Classification of Proteins) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| CATH (Classification of proteins structures) | 4R3O 4R67 5A0Q 5GJQ 5GJR 5L4G 5LE5 5LEX 5LEY 5LEZ 5LF0 5LF1 5LF3 5LF4 5LF6 5LF7 5T0C 5T0G 5T0H 5T0I 5T0J |
| Superfamily | P28072 |
| Human Protein Atlas [tissue] | ENSG00000142507-PSMB6 [tissue] |
| Peptide Atlas | P28072 |
| HPRD | 02630 |
| IPI | IPI00000811 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P28072 |
| IntAct (EBI) | P28072 |
| FunCoup | ENSG00000142507 |
| BioGRID | PSMB6 |
| STRING (EMBL) | PSMB6 |
| ZODIAC | PSMB6 |
| Ontologies - Pathways |
|---|
| QuickGO | P28072 |
| Ontology : AmiGO | MAPK cascade protein polyubiquitination proteasome complex stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent endopeptidase activity threonine-type endopeptidase activity nucleus nucleoplasm nucleoplasm cytosol cytosol proteasome core complex regulation of cellular amino acid metabolic process negative regulation of G2/M transition of mitotic cell cycle viral process protein deubiquitination proteasome core complex, beta-subunit complex anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability post-translational protein modification cadherin binding T cell receptor signaling pathway negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia extracellular exosome interleukin-1-mediated signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway regulation of hematopoietic stem cell differentiation |
| Ontology : EGO-EBI | MAPK cascade protein polyubiquitination proteasome complex stimulatory C-type lectin receptor signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent endopeptidase activity threonine-type endopeptidase activity nucleus nucleoplasm nucleoplasm cytosol cytosol proteasome core complex regulation of cellular amino acid metabolic process negative regulation of G2/M transition of mitotic cell cycle viral process protein deubiquitination proteasome core complex, beta-subunit complex anaphase-promoting complex-dependent catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process tumor necrosis factor-mediated signaling pathway NIK/NF-kappaB signaling Fc-epsilon receptor signaling pathway proteasome-mediated ubiquitin-dependent protein catabolic process regulation of mRNA stability post-translational protein modification cadherin binding T cell receptor signaling pathway negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition transmembrane transport Wnt signaling pathway, planar cell polarity pathway regulation of transcription from RNA polymerase II promoter in response to hypoxia extracellular exosome interleukin-1-mediated signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway regulation of hematopoietic stem cell differentiation |
| Pathways : BIOCARTA | Antigen Processing and Presentation [Genes] |
| Pathways : KEGG | Proteasome |
| NDEx Network | PSMB6 |
| Atlas of Cancer Signalling Network | PSMB6 |
| Wikipedia pathways | PSMB6 |
| Orthology - Evolution |
|---|
| OrthoDB | 5694 |
| GeneTree (enSembl) | ENSG00000142507 |
| Phylogenetic Trees/Animal Genes : TreeFam | PSMB6 |
| HOVERGEN | P28072 |
| HOGENOM | P28072 |
| Homologs : HomoloGene | PSMB6 |
| Homology/Alignments : Family Browser (UCSC) | PSMB6 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | PSMB6 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | PSMB6 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | PSMB6 |
| dbVar | PSMB6 |
| ClinVar | PSMB6 |
| 1000_Genomes | PSMB6 |
| Exome Variant Server | PSMB6 |
| ExAC (Exome Aggregation Consortium) | ENSG00000142507 |
| GNOMAD Browser | ENSG00000142507 |
| Genetic variants : HAPMAP | 5694 |
| Genomic Variants (DGV) | PSMB6 [DGVbeta] |
| DECIPHER | PSMB6 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | PSMB6 |
| Mutations |
|---|
| ICGC Data Portal | PSMB6 |
| TCGA Data Portal | PSMB6 |
| Broad Tumor Portal | PSMB6 |
| OASIS Portal | PSMB6 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | PSMB6 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | PSMB6 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search PSMB6 |
| DgiDB (Drug Gene Interaction Database) | PSMB6 |
| DoCM (Curated mutations) | PSMB6 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | PSMB6 (select a term) |
| intoGen | PSMB6 |
| Cancer3D | PSMB6(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600307 |
| Orphanet | |
| DisGeNET | PSMB6 |
| Medgen | PSMB6 |
| Genetic Testing Registry | PSMB6
|
| NextProt | P28072 [Medical] |
| TSGene | 5694 |
| GENETests | PSMB6 |
| Target Validation | PSMB6 |
| Huge Navigator |
PSMB6 [HugePedia] |
| snp3D : Map Gene to Disease | 5694 |
| BioCentury BCIQ | PSMB6 |
| ClinGen | PSMB6 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 5694 |
| Chemical/Pharm GKB Gene | PA33888 |
| Clinical trial | PSMB6 |
| Miscellaneous |
|---|
| canSAR (ICR) | PSMB6 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 90 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | PSMB6 |
| EVEX | PSMB6 |
| GoPubMed | PSMB6 |
| iHOP | PSMB6 |
