Atlas of Genetics and Cytogenetics in Oncology and Haematology

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PSMB6 (proteasome subunit beta 6)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)Y
DELTA
Other aliasLMPY
HGNC (Hugo) PSMB6
LocusID (NCBI) 5694
Atlas_Id 55420
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 4796144 and ends at 4798503 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		PSMB6 (17p13.2) / ANKRD27 (19q13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PSMB6   9543
Cards
Entrez_Gene (NCBI)PSMB6  5694  proteasome subunit beta 6
AliasesDELTA; LMPY; Y
GeneCards (Weizmann)PSMB6
Ensembl hg19 (Hinxton)ENSG00000142507 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142507 [Gene_View]  chr17:4796144-4798503 [Contig_View]  PSMB6 [Vega]
ICGC DataPortalENSG00000142507
TCGA cBioPortalPSMB6
AceView (NCBI)PSMB6
Genatlas (Paris)PSMB6
WikiGenes5694
SOURCE (Princeton)PSMB6
Genetics Home Reference (NIH)PSMB6
Genomic and cartography
GoldenPath hg38 (UCSC)PSMB6  -     chr17:4796144-4798503 +  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMB6  -     17p13.2   [Description]    (hg19-Feb_2009)
EnsemblPSMB6 - 17p13.2 [CytoView hg19]  PSMB6 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBIPSMB6 [Mapview hg19]  PSMB6 [Mapview hg38]
OMIM600307   
Gene and transcription
Genbank (Entrez)AK311768 BC000835 BF671774 BM553399 BQ691763
RefSeq transcript (Entrez)NM_001270481 NM_002798
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMB6
Cluster EST : UnigeneHs.77060 [ NCBI ]
CGAP (NCI)Hs.77060
Alternative Splicing GalleryENSG00000142507
Gene ExpressionPSMB6 [ NCBI-GEO ]   PSMB6 [ EBI - ARRAY_EXPRESS ]   PSMB6 [ SEEK ]   PSMB6 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMB6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5694
GTEX Portal (Tissue expression)PSMB6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28072   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28072  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28072
Splice isoforms : SwissVarP28072
PhosPhoSitePlusP28072
Domaine pattern : Prosite (Expaxy)PROTEASOME_BETA_1 (PS00854)    PROTEASOME_BETA_2 (PS51476)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Pept_T1A_subB    Proteasome_bsu_CS    Proteasome_sua/b    Proteasome_suB-type   
Domain families : Pfam (Sanger)Proteasome (PF00227)   
Domain families : Pfam (NCBI)pfam00227   
Conserved Domain (NCBI)PSMB6
DMDM Disease mutations5694
Blocks (Seattle)PSMB6
PDB (SRS)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (PDBSum)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (IMB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (RSDB)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
Structural Biology KnowledgeBase4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SCOP (Structural Classification of Proteins)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
CATH (Classification of proteins structures)4R3O    4R67    5A0Q    5GJQ    5GJR    5L4G    5LE5    5LEX    5LEY    5LEZ    5LF0    5LF1    5LF3    5LF4    5LF6    5LF7    5T0C    5T0G    5T0H    5T0I    5T0J   
SuperfamilyP28072
Human Protein AtlasENSG00000142507
Peptide AtlasP28072
HPRD02630
IPIIPI00000811   
Protein Interaction databases
DIP (DOE-UCLA)P28072
IntAct (EBI)P28072
FunCoupENSG00000142507
BioGRIDPSMB6
STRING (EMBL)PSMB6
ZODIACPSMB6
Ontologies - Pathways
QuickGOP28072
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  endopeptidase activity  threonine-type endopeptidase activity  nucleus  nucleoplasm  nucleoplasm  cytosol  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  negative regulation of G2/M transition of mitotic cell cycle  viral process  protein deubiquitination  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  cadherin binding  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  endopeptidase activity  threonine-type endopeptidase activity  nucleus  nucleoplasm  nucleoplasm  cytosol  cytosol  proteasome core complex  regulation of cellular amino acid metabolic process  negative regulation of G2/M transition of mitotic cell cycle  viral process  protein deubiquitination  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  cadherin binding  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Pathways : BIOCARTAAntigen Processing and Presentation [Genes]   
Pathways : KEGGProteasome   
NDEx NetworkPSMB6
Atlas of Cancer Signalling NetworkPSMB6
Wikipedia pathwaysPSMB6
Orthology - Evolution
OrthoDB5694
GeneTree (enSembl)ENSG00000142507
Phylogenetic Trees/Animal Genes : TreeFamPSMB6
HOVERGENP28072
HOGENOMP28072
Homologs : HomoloGenePSMB6
Homology/Alignments : Family Browser (UCSC)PSMB6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMB6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMB6
dbVarPSMB6
ClinVarPSMB6
1000_GenomesPSMB6 
Exome Variant ServerPSMB6
ExAC (Exome Aggregation Consortium)PSMB6 (select the gene name)
Genetic variants : HAPMAP5694
Genomic Variants (DGV)PSMB6 [DGVbeta]
DECIPHERPSMB6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMB6 
Mutations
ICGC Data PortalPSMB6 
TCGA Data PortalPSMB6 
Broad Tumor PortalPSMB6
OASIS PortalPSMB6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMB6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMB6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMB6
DgiDB (Drug Gene Interaction Database)PSMB6
DoCM (Curated mutations)PSMB6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMB6 (select a term)
intoGenPSMB6
Cancer3DPSMB6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600307   
Orphanet
MedgenPSMB6
Genetic Testing Registry PSMB6
NextProtP28072 [Medical]
TSGene5694
GENETestsPSMB6
Target ValidationPSMB6
Huge Navigator PSMB6 [HugePedia]
snp3D : Map Gene to Disease5694
BioCentury BCIQPSMB6
ClinGenPSMB6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5694
Chemical/Pharm GKB GenePA33888
Clinical trialPSMB6
Miscellaneous
canSAR (ICR)PSMB6 (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMB6
EVEXPSMB6
GoPubMedPSMB6
iHOPPSMB6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:26:54 CEST 2017
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