Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PSMB9 (proteasome subunit beta 9)

Identity

Alias_namesLMP2
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2)
large multifunctional peptidase 2
proteasome (prosome, macropain) subunit, beta type, 9
Alias_symbol (synonym)RING12
beta1i
PSMB6i
Other aliasPRAAS3
HGNC (Hugo) PSMB9
LocusID (NCBI) 5698
Atlas_Id 45739
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 32854161 and ends at 32859851 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMB9   9546
Cards
Entrez_Gene (NCBI)PSMB9  5698  proteasome subunit beta 9
AliasesLMP2; PRAAS3; PSMB6i; RING12; 
beta1i
GeneCards (Weizmann)PSMB9
Ensembl hg19 (Hinxton)ENSG00000240065 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000240065 [Gene_View]  ENSG00000240065 [Sequence]  chr6:32854161-32859851 [Contig_View]  PSMB9 [Vega]
ICGC DataPortalENSG00000240065
TCGA cBioPortalPSMB9
AceView (NCBI)PSMB9
Genatlas (Paris)PSMB9
WikiGenes5698
SOURCE (Princeton)PSMB9
Genetics Home Reference (NIH)PSMB9
Genomic and cartography
GoldenPath hg38 (UCSC)PSMB9  -     chr6:32854161-32859851 +  6p21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMB9  -     6p21.32   [Description]    (hg19-Feb_2009)
EnsemblPSMB9 - 6p21.32 [CytoView hg19]  PSMB9 - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBIPSMB9 [Mapview hg19]  PSMB9 [Mapview hg38]
OMIM177045   617591   
Gene and transcription
Genbank (Entrez)AI310206 AK303118 BC065513 BF513693 BI832878
RefSeq transcript (Entrez)NM_002800 NM_148954
RefSeq genomic (Entrez)NC_000006 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)PSMB9
Cluster EST : UnigeneHs.654585 [ NCBI ]
CGAP (NCI)Hs.654585
Alternative Splicing GalleryENSG00000240065
Gene ExpressionPSMB9 [ NCBI-GEO ]   PSMB9 [ EBI - ARRAY_EXPRESS ]   PSMB9 [ SEEK ]   PSMB9 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMB9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5698
GTEX Portal (Tissue expression)PSMB9
Human Protein AtlasENSG00000240065-PSMB9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28065   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28065  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28065
Splice isoforms : SwissVarP28065
Catalytic activity : Enzyme3.4.25.1 [ Enzyme-Expasy ]   3.4.25.13.4.25.1 [ IntEnz-EBI ]   3.4.25.1 [ BRENDA ]   3.4.25.1 [ KEGG ]   
PhosPhoSitePlusP28065
Domaine pattern : Prosite (Expaxy)PROTEASOME_BETA_1 (PS00854)    PROTEASOME_BETA_2 (PS51476)   
Domains : Interpro (EBI)Ntn_hydrolases_N    Pept_T1A_subB    Proteasome_beta9    Proteasome_bsu_CS    Proteasome_sua/b    Proteasome_suB-type   
Domain families : Pfam (Sanger)Proteasome (PF00227)   
Domain families : Pfam (NCBI)pfam00227   
Conserved Domain (NCBI)PSMB9
DMDM Disease mutations5698
Blocks (Seattle)PSMB9
PDB (SRS)6AVO   
PDB (PDBSum)6AVO   
PDB (IMB)6AVO   
PDB (RSDB)6AVO   
Structural Biology KnowledgeBase6AVO   
SCOP (Structural Classification of Proteins)6AVO   
CATH (Classification of proteins structures)6AVO   
SuperfamilyP28065
Human Protein Atlas [tissue]ENSG00000240065-PSMB9 [tissue]
Peptide AtlasP28065
HPRD01514
IPIIPI00000787   IPI00170899   IPI00894395   IPI00797045   IPI01015769   IPI00796431   IPI00893109   IPI00893456   IPI00893267   
Protein Interaction databases
DIP (DOE-UCLA)P28065
IntAct (EBI)P28065
FunCoupENSG00000240065
BioGRIDPSMB9
STRING (EMBL)PSMB9
ZODIACPSMB9
Ontologies - Pathways
QuickGOP28065
Ontology : AmiGOproteasome complex  immune system process  endopeptidase activity  threonine-type endopeptidase activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  proteasome core complex  proteasome core complex  proteasomal protein catabolic process  proteasomal ubiquitin-independent protein catabolic process  viral process  protein deubiquitination  proteasome core complex, beta-subunit complex  proteasome-mediated ubiquitin-dependent protein catabolic process  post-translational protein modification  extracellular exosome  spermatoproteasome complex  regulation of cysteine-type endopeptidase activity  
Ontology : EGO-EBIproteasome complex  immune system process  endopeptidase activity  threonine-type endopeptidase activity  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  proteasome core complex  proteasome core complex  proteasomal protein catabolic process  proteasomal ubiquitin-independent protein catabolic process  viral process  protein deubiquitination  proteasome core complex, beta-subunit complex  proteasome-mediated ubiquitin-dependent protein catabolic process  post-translational protein modification  extracellular exosome  spermatoproteasome complex  regulation of cysteine-type endopeptidase activity  
Pathways : KEGGProteasome   
NDEx NetworkPSMB9
Atlas of Cancer Signalling NetworkPSMB9
Wikipedia pathwaysPSMB9
Orthology - Evolution
OrthoDB5698
GeneTree (enSembl)ENSG00000240065
Phylogenetic Trees/Animal Genes : TreeFamPSMB9
HOVERGENP28065
HOGENOMP28065
Homologs : HomoloGenePSMB9
Homology/Alignments : Family Browser (UCSC)PSMB9
Gene fusions - Rearrangements
Fusion : QuiverPSMB9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMB9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMB9
dbVarPSMB9
ClinVarPSMB9
1000_GenomesPSMB9 
Exome Variant ServerPSMB9
ExAC (Exome Aggregation Consortium)ENSG00000240065
GNOMAD BrowserENSG00000240065
Varsome BrowserPSMB9
Genetic variants : HAPMAP5698
Genomic Variants (DGV)PSMB9 [DGVbeta]
DECIPHERPSMB9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMB9 
Mutations
ICGC Data PortalPSMB9 
TCGA Data PortalPSMB9 
Broad Tumor PortalPSMB9
OASIS PortalPSMB9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMB9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMB9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMB9
DgiDB (Drug Gene Interaction Database)PSMB9
DoCM (Curated mutations)PSMB9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMB9 (select a term)
intoGenPSMB9
Cancer3DPSMB9(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM177045    617591   
Orphanet
DisGeNETPSMB9
MedgenPSMB9
Genetic Testing Registry PSMB9
NextProtP28065 [Medical]
TSGene5698
GENETestsPSMB9
Target ValidationPSMB9
Huge Navigator PSMB9 [HugePedia]
snp3D : Map Gene to Disease5698
BioCentury BCIQPSMB9
ClinGenPSMB9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5698
Chemical/Pharm GKB GenePA33891
Clinical trialPSMB9
Miscellaneous
canSAR (ICR)PSMB9 (select the gene name)
Probes
Litterature
PubMed129 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMB9
EVEXPSMB9
GoPubMedPSMB9
iHOPPSMB9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:32:54 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.