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PSMD10 (proteasome 26S subunit, non-ATPase 10)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)p28
Other aliasdJ889N15.2
p28(GANK)
HGNC (Hugo) PSMD10
LocusID (NCBI) 5716
Atlas_Id 41887
Location Xq22.3  [Link to chromosome band Xq22]
Location_base_pair Starts at 107327435 and ends at 107334874 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNG4 (1q42.3) / PSMD10 (Xq22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMD10   9555
Cards
Entrez_Gene (NCBI)PSMD10  5716  proteasome 26S subunit, non-ATPase 10
AliasesdJ889N15.2; p28; p28(GANK)
GeneCards (Weizmann)PSMD10
Ensembl hg19 (Hinxton)ENSG00000101843 [Gene_View]  chrX:107327435-107334874 [Contig_View]  PSMD10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000101843 [Gene_View]  chrX:107327435-107334874 [Contig_View]  PSMD10 [Vega]
ICGC DataPortalENSG00000101843
TCGA cBioPortalPSMD10
AceView (NCBI)PSMD10
Genatlas (Paris)PSMD10
WikiGenes5716
SOURCE (Princeton)PSMD10
Genetics Home Reference (NIH)PSMD10
Genomic and cartography
GoldenPath hg19 (UCSC)PSMD10  -     chrX:107327435-107334874 -  Xq22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PSMD10  -     Xq22.3   [Description]    (hg38-Dec_2013)
EnsemblPSMD10 - Xq22.3 [CytoView hg19]  PSMD10 - Xq22.3 [CytoView hg38]
Mapping of homologs : NCBIPSMD10 [Mapview hg19]  PSMD10 [Mapview hg38]
OMIM300880   
Gene and transcription
Genbank (Entrez)AB009619 AK058108 AK295996 AK309326 AY057056
RefSeq transcript (Entrez)NM_002814 NM_170750
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_012521 NT_011651 NW_004929444
Consensus coding sequences : CCDS (NCBI)PSMD10
Cluster EST : UnigeneHs.522752 [ NCBI ]
CGAP (NCI)Hs.522752
Alternative Splicing GalleryENSG00000101843
Gene ExpressionPSMD10 [ NCBI-GEO ]   PSMD10 [ EBI - ARRAY_EXPRESS ]   PSMD10 [ SEEK ]   PSMD10 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMD10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5716
GTEX Portal (Tissue expression)PSMD10
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75832   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75832  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75832
Splice isoforms : SwissVarO75832
PhosPhoSitePlusO75832
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domain families : Pfam (Sanger)Ank_2 (PF12796)   
Domain families : Pfam (NCBI)pfam12796   
Domain families : Smart (EMBL)ANK (SM00248)  
Conserved Domain (NCBI)PSMD10
DMDM Disease mutations5716
Blocks (Seattle)PSMD10
PDB (SRS)1QYM    1TR4    1UOH    4NIK   
PDB (PDBSum)1QYM    1TR4    1UOH    4NIK   
PDB (IMB)1QYM    1TR4    1UOH    4NIK   
PDB (RSDB)1QYM    1TR4    1UOH    4NIK   
Structural Biology KnowledgeBase1QYM    1TR4    1UOH    4NIK   
SCOP (Structural Classification of Proteins)1QYM    1TR4    1UOH    4NIK   
CATH (Classification of proteins structures)1QYM    1TR4    1UOH    4NIK   
SuperfamilyO75832
Human Protein AtlasENSG00000101843
Peptide AtlasO75832
HPRD04594
IPIIPI00003565   IPI00552808   IPI00183104   IPI00552190   IPI00647839   IPI00027699   
Protein Interaction databases
DIP (DOE-UCLA)O75832
IntAct (EBI)O75832
FunCoupENSG00000101843
BioGRIDPSMD10
STRING (EMBL)PSMD10
ZODIACPSMD10
Ontologies - Pathways
QuickGOO75832
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  MAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  proteasome regulatory particle  regulation of cellular amino acid metabolic process  apoptotic process  cytoplasmic sequestering of NF-kappaB  transcription factor binding  proteasome regulatory particle, base subcomplex  positive regulation of cell growth  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  positive regulation of protein ubiquitination  negative regulation of NF-kappaB transcription factor activity  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  negative regulation of apoptotic process  negative regulation of apoptotic process  proteasome-mediated ubiquitin-dependent protein catabolic process  negative regulation of MAPK cascade  regulation of mRNA stability  negative regulation of DNA damage response, signal transduction by p53 class mediator  intermediate filament cytoskeleton  positive regulation of cyclin-dependent protein serine/threonine kinase activity  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  Wnt signaling pathway, planar cell polarity pathway  proteasome regulatory particle assembly  negative regulation of canonical Wnt signaling pathway  negative regulation of release of cytochrome c from mitochondria  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  MAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  proteasome regulatory particle  regulation of cellular amino acid metabolic process  apoptotic process  cytoplasmic sequestering of NF-kappaB  transcription factor binding  proteasome regulatory particle, base subcomplex  positive regulation of cell growth  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  positive regulation of protein ubiquitination  negative regulation of NF-kappaB transcription factor activity  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  negative regulation of apoptotic process  negative regulation of apoptotic process  proteasome-mediated ubiquitin-dependent protein catabolic process  negative regulation of MAPK cascade  regulation of mRNA stability  negative regulation of DNA damage response, signal transduction by p53 class mediator  intermediate filament cytoskeleton  positive regulation of cyclin-dependent protein serine/threonine kinase activity  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  Wnt signaling pathway, planar cell polarity pathway  proteasome regulatory particle assembly  negative regulation of canonical Wnt signaling pathway  negative regulation of release of cytochrome c from mitochondria  positive regulation of canonical Wnt signaling pathway  
NDEx NetworkPSMD10
Atlas of Cancer Signalling NetworkPSMD10
Wikipedia pathwaysPSMD10
Orthology - Evolution
OrthoDB5716
GeneTree (enSembl)ENSG00000101843
Phylogenetic Trees/Animal Genes : TreeFamPSMD10
HOVERGENO75832
HOGENOMO75832
Homologs : HomoloGenePSMD10
Homology/Alignments : Family Browser (UCSC)PSMD10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMD10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMD10
dbVarPSMD10
ClinVarPSMD10
1000_GenomesPSMD10 
Exome Variant ServerPSMD10
ExAC (Exome Aggregation Consortium)PSMD10 (select the gene name)
Genetic variants : HAPMAP5716
Genomic Variants (DGV)PSMD10 [DGVbeta]
DECIPHER (Syndromes)X:107327435-107334874  ENSG00000101843
CONAN: Copy Number AnalysisPSMD10 
Mutations
ICGC Data PortalPSMD10 
TCGA Data PortalPSMD10 
Broad Tumor PortalPSMD10
OASIS PortalPSMD10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMD10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMD10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch PSMD10
DgiDB (Drug Gene Interaction Database)PSMD10
DoCM (Curated mutations)PSMD10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMD10 (select a term)
intoGenPSMD10
Cancer3DPSMD10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300880   
Orphanet
MedgenPSMD10
Genetic Testing Registry PSMD10
NextProtO75832 [Medical]
TSGene5716
GENETestsPSMD10
Huge Navigator PSMD10 [HugePedia]
snp3D : Map Gene to Disease5716
BioCentury BCIQPSMD10
ClinGenPSMD10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5716
Chemical/Pharm GKB GenePA33900
Clinical trialPSMD10
Miscellaneous
canSAR (ICR)PSMD10 (select the gene name)
Probes
Litterature
PubMed114 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMD10
EVEXPSMD10
GoPubMedPSMD10
iHOPPSMD10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:16:02 CEST 2017

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