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PSMD10 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 10)

Identity

Other namesdJ889N15.2
p28
p28(GANK)
HGNC (Hugo) PSMD10
LocusID (NCBI) 5716
Location Xq22.3
Location_base_pair Starts at 107327435 and ends at 107334874 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PSMD10   9555
Entrez_Gene (NCBI)PSMD10  5716  proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
Cards
GeneCards (Weizmann)PSMD10
Ensembl (Hinxton)ENSG00000101843 [Gene_View]  chrX:107327435-107334874 [Contig_View]  PSMD10 [Vega]
AceView (NCBI)PSMD10
Genatlas (Paris)PSMD10
SOURCE (Stanford)NM_002814 NM_170750
Genomic and cartography
GoldenPath (UCSC)PSMD10  -  Xq22.3   chrX:107327435-107334874 -  Xq22.3   [Description]    (hg19-Feb_2009)
EnsemblPSMD10 - Xq22.3 [CytoView]
Mapping of homologs : NCBIPSMD10 [Mapview]
OMIM603480   
Gene and transcription
Genbank (Entrez)AB009619 AK058108 AK295996 AK309326 AY057056
RefSeq transcript (SRS)NM_002814 NM_170750
RefSeq transcript (Entrez)NM_002814 NM_170750
RefSeq genomic (SRS)AC_000155 NC_000023 NC_018934 NG_012521 NT_011651 NW_001842391 NW_004078123
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_012521 NT_011651 NW_001842391 NW_004078123
Consensus coding sequences : CCDS (NCBI)PSMD10
Cluster EST : UnigeneHs.522752 [ SRS ] Hs.522752 [ NCBI ]
CGAP (NCI)Hs.522752
Alternative Splicing : Fast-db (Paris)GSHG0032264
Alternative Splicing GalleryENSG00000101843
Gene ExpressionPSMD10 [ NCBI-GEO ]   PSMD10 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75832 (SRS) O75832 (Uniprot)
NextProtO75832
With graphics : InterProO75832
Splice isoforms : SwissVarO75832(Swissvar)
Domaine pattern : Prosite (SRS)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domaine pattern : Prosite (Expaxy)ANK_REP_REGION (PS50297)    ANK_REPEAT (PS50088)   
Domains : Interpro (SRS)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Domains : Interpro (EBI)Ankyrin_rpt    Ankyrin_rpt-contain_dom   
Related proteins : CluSTrO75832
Domain families : Pfam (SRS)Ank (PF00023)   
Domain families : Pfam (Sanger)Ank (PF00023)   
Domain families : Pfam (NCBI)pfam00023   
Domain families : Smart (EMBL)ANK (SM00248)  
DMDM5716
Blocks (Seattle)O75832
PDB (SRS)1QYM    1TR4    1UOH   
PDB (PDBSum)1QYM    1TR4    1UOH   
PDB (IMB)1QYM    1TR4    1UOH   
PDB (RSDB)1QYM    1TR4    1UOH   
Human Protein AtlasENSG00000101843
HPRD04594
IPIIPI00003565   IPI00552808   IPI00183104   IPI00552190   IPI00647839   IPI00027699   
Protein Interaction databases
DIP (DOE-UCLA)O75832
IntAct (EBI)O75832
FunCoupENSG00000101843
REACTOMEPSMD10
Protein Interaction Database5716
BioGRIDPSMD10
InParanoidO75832
Interologous Interaction database O75832
IntegromeDBPSMD10
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PSMD10
SNP (GeneSNP Utah)PSMD10
SNP : HGBasePSMD10
Genetic variants : HAPMAPPSMD10
Somatic Mutations in Cancer : COSMICPSMD10 
CONAN: Copy Number AnalysisPSMD10 
Mutations and Diseases : HGMDPSMD10
OMIM603480   
GENETests603480   
Disease Genetic AssociationPSMD10
Huge Navigator PSMD10 [HugePedia]  PSMD10 [HugeCancerGEM]
Genomic VariantsPSMD10  PSMD10 [DGVbeta]
snp3D : Map Gene to Disease5716
General knowledge
Homologs : HomoloGenePSMD10
Homology/Alignments : Family Browser (UCSC)PSMD10
Phylogenetic Trees/Animal Genes : TreeFamPSMD10
Chemical/Protein Interactions : CTD5716
Chemical/Pharm GKB GenePA33900
Clinical trialPSMD10
Cancer Resource (Charite)ENSG00000101843
Ontology : AmiGOcell cycle checkpoint  G1/S transition of mitotic cell cycle  S phase of mitotic cell cycle  negative regulation of transcription from RNA polymerase II promoter  protein polyubiquitination  M/G1 transition of mitotic cell cycle  mitotic cell cycle  proteasome complex  antigen processing and presentation of peptide antigen via MHC class I  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  proteasome regulatory particle  regulation of cellular amino acid metabolic process  apoptotic process  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  cytoplasmic sequestering of NF-kappaB  transcription factor binding  proteasome regulatory particle, base subcomplex  gene expression  actin cytoskeleton  viral reproduction  RNA metabolic process  mRNA metabolic process  positive regulation of cell growth  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  positive regulation of protein ubiquitination  negative regulation of NF-kappaB transcription factor activity  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  cellular nitrogen compound metabolic process  antigen processing and presentation of exogenous peptide antigen via MHC class I  regulation of apoptotic process  negative regulation of apoptotic process  negative regulation of apoptotic process  negative regulation of MAPK cascade  negative regulation of DNA damage response, signal transduction by p53 class mediator  small molecule metabolic process  intermediate filament cytoskeleton  positive regulation of cyclin-dependent protein kinase activity  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  proteasome regulatory particle assembly  negative regulation of release of cytochrome c from mitochondria  
Ontology : EGO-EBIcell cycle checkpoint  G1/S transition of mitotic cell cycle  S phase of mitotic cell cycle  negative regulation of transcription from RNA polymerase II promoter  protein polyubiquitination  M/G1 transition of mitotic cell cycle  mitotic cell cycle  proteasome complex  antigen processing and presentation of peptide antigen via MHC class I  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  nucleus  nucleoplasm  cytoplasm  cytosol  proteasome regulatory particle  regulation of cellular amino acid metabolic process  apoptotic process  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  cytoplasmic sequestering of NF-kappaB  transcription factor binding  proteasome regulatory particle, base subcomplex  gene expression  actin cytoskeleton  viral reproduction  RNA metabolic process  mRNA metabolic process  positive regulation of cell growth  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  positive regulation of protein ubiquitination  negative regulation of NF-kappaB transcription factor activity  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  cellular nitrogen compound metabolic process  antigen processing and presentation of exogenous peptide antigen via MHC class I  regulation of apoptotic process  negative regulation of apoptotic process  negative regulation of apoptotic process  negative regulation of MAPK cascade  negative regulation of DNA damage response, signal transduction by p53 class mediator  small molecule metabolic process  intermediate filament cytoskeleton  positive regulation of cyclin-dependent protein kinase activity  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  proteasome regulatory particle assembly  negative regulation of release of cytochrome c from mitochondria  
Other databases
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
PubGenePSMD10
iHOPPSMD10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:49:28 CEST 2013

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