Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PSMD12 (proteasome 26S subunit, non-ATPase 12)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)p55
Rpn5
Other alias
HGNC (Hugo) PSMD12
LocusID (NCBI) 5718
Atlas_Id 55415
Location 17q24.2  [Link to chromosome band 17q24]
Location_base_pair Starts at 65334032 and ends at 65362743 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ABAT (16p13.2) / PSMD12 (17q24.2)BAIAP2 (17q25.3) / PSMD12 (17q24.2)PSMD12 (17q24.2) / KIAA2022 (Xq13.3)
PSMD12 (17q24.2) / PITPNC1 (17q24.2)SUPT4H1 (17q22) / PSMD12 (17q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMD12   9557
Cards
Entrez_Gene (NCBI)PSMD12  5718  proteasome 26S subunit, non-ATPase 12
AliasesRpn5; p55
GeneCards (Weizmann)PSMD12
Ensembl hg19 (Hinxton)ENSG00000197170 [Gene_View]  chr17:65334032-65362743 [Contig_View]  PSMD12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197170 [Gene_View]  chr17:65334032-65362743 [Contig_View]  PSMD12 [Vega]
ICGC DataPortalENSG00000197170
TCGA cBioPortalPSMD12
AceView (NCBI)PSMD12
Genatlas (Paris)PSMD12
WikiGenes5718
SOURCE (Princeton)PSMD12
Genetics Home Reference (NIH)PSMD12
Genomic and cartography
GoldenPath hg19 (UCSC)PSMD12  -     chr17:65334032-65362743 -  17q24.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PSMD12  -     17q24.2   [Description]    (hg38-Dec_2013)
EnsemblPSMD12 - 17q24.2 [CytoView hg19]  PSMD12 - 17q24.2 [CytoView hg38]
Mapping of homologs : NCBIPSMD12 [Mapview hg19]  PSMD12 [Mapview hg38]
OMIM604450   
Gene and transcription
Genbank (Entrez)AB003103 AK091198 AK222679 AK307821 AK308883
RefSeq transcript (Entrez)NM_001316341 NM_002816 NM_174871
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NW_004929407
Consensus coding sequences : CCDS (NCBI)PSMD12
Cluster EST : UnigeneHs.592689 [ NCBI ]
CGAP (NCI)Hs.592689
Alternative Splicing GalleryENSG00000197170
Gene ExpressionPSMD12 [ NCBI-GEO ]   PSMD12 [ EBI - ARRAY_EXPRESS ]   PSMD12 [ SEEK ]   PSMD12 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMD12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5718
GTEX Portal (Tissue expression)PSMD12
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00232   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00232  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00232
Splice isoforms : SwissVarO00232
PhosPhoSitePlusO00232
Domains : Interpro (EBI)PCI_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)PCI (PF01399)   
Domain families : Pfam (NCBI)pfam01399   
Domain families : Smart (EMBL)PINT (SM00088)  
Conserved Domain (NCBI)PSMD12
DMDM Disease mutations5718
Blocks (Seattle)PSMD12
SuperfamilyO00232
Human Protein AtlasENSG00000197170
Peptide AtlasO00232
HPRD05120
IPIIPI00185374   IPI00335069   
Protein Interaction databases
DIP (DOE-UCLA)O00232
IntAct (EBI)O00232
FunCoupENSG00000197170
BioGRIDPSMD12
STRING (EMBL)PSMD12
ZODIACPSMD12
Ontologies - Pathways
QuickGOO00232
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  nucleoplasm  cytoplasm  cytosol  proteasome regulatory particle  regulation of cellular amino acid metabolic process  proteasome regulatory particle, lid subcomplex  membrane  proteasome accessory complex  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  nuclear proteasome complex  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  Wnt signaling pathway, planar cell polarity pathway  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  nucleoplasm  cytoplasm  cytosol  proteasome regulatory particle  regulation of cellular amino acid metabolic process  proteasome regulatory particle, lid subcomplex  membrane  proteasome accessory complex  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process  nuclear proteasome complex  tumor necrosis factor-mediated signaling pathway  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  Wnt signaling pathway, planar cell polarity pathway  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  
Pathways : KEGGProteasome    Epstein-Barr virus infection   
NDEx NetworkPSMD12
Atlas of Cancer Signalling NetworkPSMD12
Wikipedia pathwaysPSMD12
Orthology - Evolution
OrthoDB5718
GeneTree (enSembl)ENSG00000197170
Phylogenetic Trees/Animal Genes : TreeFamPSMD12
HOVERGENO00232
HOGENOMO00232
Homologs : HomoloGenePSMD12
Homology/Alignments : Family Browser (UCSC)PSMD12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMD12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMD12
dbVarPSMD12
ClinVarPSMD12
1000_GenomesPSMD12 
Exome Variant ServerPSMD12
ExAC (Exome Aggregation Consortium)PSMD12 (select the gene name)
Genetic variants : HAPMAP5718
Genomic Variants (DGV)PSMD12 [DGVbeta]
DECIPHER (Syndromes)17:65334032-65362743  ENSG00000197170
CONAN: Copy Number AnalysisPSMD12 
Mutations
ICGC Data PortalPSMD12 
TCGA Data PortalPSMD12 
Broad Tumor PortalPSMD12
OASIS PortalPSMD12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMD12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMD12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMD12
DgiDB (Drug Gene Interaction Database)PSMD12
DoCM (Curated mutations)PSMD12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMD12 (select a term)
intoGenPSMD12
Cancer3DPSMD12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604450   
Orphanet
MedgenPSMD12
Genetic Testing Registry PSMD12
NextProtO00232 [Medical]
TSGene5718
GENETestsPSMD12
Huge Navigator PSMD12 [HugePedia]
snp3D : Map Gene to Disease5718
BioCentury BCIQPSMD12
ClinGenPSMD12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5718
Chemical/Pharm GKB GenePA33903
Clinical trialPSMD12
Miscellaneous
canSAR (ICR)PSMD12 (select the gene name)
Probes
Litterature
PubMed83 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMD12
EVEXPSMD12
GoPubMedPSMD12
iHOPPSMD12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:23:23 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.