Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PSMD6 (proteasome 26S subunit, non-ATPase 6)

Identity

Alias_namesproteasome (prosome
Alias_symbol (synonym)S10
p44S10
KIAA0107
Rpn7
Other aliasSGA-113M
p42A
HGNC (Hugo) PSMD6
LocusID (NCBI) 9861
Atlas_Id 55439
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 64010549 and ends at 64023606 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MCC (5q22.2) / PSMD6 (3p14.1)PSMD6 (3p14.1) / EIF3A (10q26.11)PSMD6 (3p14.1) / ZNF646 (16p11.2)
ZNF646 (16p11.2) / PSMD6 (3p14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSMD6   9564
Cards
Entrez_Gene (NCBI)PSMD6  9861  proteasome 26S subunit, non-ATPase 6
AliasesRpn7; S10; SGA-113M; p42A; 
p44S10
GeneCards (Weizmann)PSMD6
Ensembl hg19 (Hinxton)ENSG00000163636 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163636 [Gene_View]  chr3:64010549-64023606 [Contig_View]  PSMD6 [Vega]
ICGC DataPortalENSG00000163636
TCGA cBioPortalPSMD6
AceView (NCBI)PSMD6
Genatlas (Paris)PSMD6
WikiGenes9861
SOURCE (Princeton)PSMD6
Genetics Home Reference (NIH)PSMD6
Genomic and cartography
GoldenPath hg38 (UCSC)PSMD6  -     chr3:64010549-64023606 -  3p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMD6  -     3p14.1   [Description]    (hg19-Feb_2009)
EnsemblPSMD6 - 3p14.1 [CytoView hg19]  PSMD6 - 3p14.1 [CytoView hg38]
Mapping of homologs : NCBIPSMD6 [Mapview hg19]  PSMD6 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF215935 AF530062 AK054730 AK055210 AK095059
RefSeq transcript (Entrez)NM_001271779 NM_001271780 NM_001271781 NM_014814
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMD6
Cluster EST : UnigeneHs.152536 [ NCBI ]
CGAP (NCI)Hs.152536
Alternative Splicing GalleryENSG00000163636
Gene ExpressionPSMD6 [ NCBI-GEO ]   PSMD6 [ EBI - ARRAY_EXPRESS ]   PSMD6 [ SEEK ]   PSMD6 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMD6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9861
GTEX Portal (Tissue expression)PSMD6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15008   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15008  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15008
Splice isoforms : SwissVarQ15008
PhosPhoSitePlusQ15008
Domains : Interpro (EBI)PCI_dom    Rpn7/CSN1    TPR-like_helical_dom    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)PCI (PF01399)    RPN7 (PF10602)   
Domain families : Pfam (NCBI)pfam01399    pfam10602   
Domain families : Smart (EMBL)PINT (SM00088)  
Conserved Domain (NCBI)PSMD6
DMDM Disease mutations9861
Blocks (Seattle)PSMD6
PDB (SRS)5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (PDBSum)5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (IMB)5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
PDB (RSDB)5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
Structural Biology KnowledgeBase5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
SCOP (Structural Classification of Proteins)5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
CATH (Classification of proteins structures)5GJQ    5GJR    5L4K    5T0C    5T0G    5T0H    5T0I    5T0J   
SuperfamilyQ15008
Human Protein AtlasENSG00000163636
Peptide AtlasQ15008
HPRD18370
IPIIPI00014151   IPI00794383   IPI00793381   IPI00945689   IPI00947396   IPI00793676   
Protein Interaction databases
DIP (DOE-UCLA)Q15008
IntAct (EBI)Q15008
FunCoupENSG00000163636
BioGRIDPSMD6
STRING (EMBL)PSMD6
ZODIACPSMD6
Ontologies - Pathways
QuickGOQ15008
Ontology : AmiGOMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  extracellular region  nucleoplasm  cytosol  proteasome regulatory particle  proteolysis  regulation of cellular amino acid metabolic process  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  ATPase activity  proteasome accessory complex  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  secretory granule lumen  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  ficolin-1-rich granule lumen  
Ontology : EGO-EBIMAPK cascade  protein polyubiquitination  proteasome complex  stimulatory C-type lectin receptor signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  protein binding  extracellular region  nucleoplasm  cytosol  proteasome regulatory particle  proteolysis  regulation of cellular amino acid metabolic process  negative regulation of G2/M transition of mitotic cell cycle  protein deubiquitination  ATPase activity  proteasome accessory complex  anaphase-promoting complex-dependent catabolic process  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  tumor necrosis factor-mediated signaling pathway  secretory granule lumen  NIK/NF-kappaB signaling  Fc-epsilon receptor signaling pathway  proteasome-mediated ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  neutrophil degranulation  regulation of mRNA stability  T cell receptor signaling pathway  negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle  positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition  transmembrane transport  Wnt signaling pathway, planar cell polarity pathway  regulation of transcription from RNA polymerase II promoter in response to hypoxia  extracellular exosome  negative regulation of canonical Wnt signaling pathway  positive regulation of canonical Wnt signaling pathway  ficolin-1-rich granule lumen  
Pathways : KEGGProteasome    Epstein-Barr virus infection   
NDEx NetworkPSMD6
Atlas of Cancer Signalling NetworkPSMD6
Wikipedia pathwaysPSMD6
Orthology - Evolution
OrthoDB9861
GeneTree (enSembl)ENSG00000163636
Phylogenetic Trees/Animal Genes : TreeFamPSMD6
HOVERGENQ15008
HOGENOMQ15008
Homologs : HomoloGenePSMD6
Homology/Alignments : Family Browser (UCSC)PSMD6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMD6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMD6
dbVarPSMD6
ClinVarPSMD6
1000_GenomesPSMD6 
Exome Variant ServerPSMD6
ExAC (Exome Aggregation Consortium)PSMD6 (select the gene name)
Genetic variants : HAPMAP9861
Genomic Variants (DGV)PSMD6 [DGVbeta]
DECIPHERPSMD6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMD6 
Mutations
ICGC Data PortalPSMD6 
TCGA Data PortalPSMD6 
Broad Tumor PortalPSMD6
OASIS PortalPSMD6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMD6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMD6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMD6
DgiDB (Drug Gene Interaction Database)PSMD6
DoCM (Curated mutations)PSMD6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMD6 (select a term)
intoGenPSMD6
Cancer3DPSMD6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenPSMD6
Genetic Testing Registry PSMD6
NextProtQ15008 [Medical]
TSGene9861
GENETestsPSMD6
Target ValidationPSMD6
Huge Navigator PSMD6 [HugePedia]
snp3D : Map Gene to Disease9861
BioCentury BCIQPSMD6
ClinGenPSMD6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9861
Chemical/Pharm GKB GenePA33910
Clinical trialPSMD6
Miscellaneous
canSAR (ICR)PSMD6 (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMD6
EVEXPSMD6
GoPubMedPSMD6
iHOPPSMD6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:27:00 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.