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PSMG4 (proteasome assembly chaperone 4)

Identity

Alias_namesC6orf86
chromosome 6 open reading frame 86
proteasome (prosome, macropain) assembly chaperone 4
Alias_symbol (synonym)PAC4
Other aliasbA506K6.2
HGNC (Hugo) PSMG4
LocusID (NCBI) 389362
Atlas_Id 78469
Location 6p25.2  [Link to chromosome band 6p25]
Location_base_pair Starts at 3258928 and ends at 3268066 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPS6KA2 (6q27) / PSMG4 (6p25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p25;q27) RPS6KA2/PSMG4


External links

Nomenclature
HGNC (Hugo)PSMG4   21108
Cards
Entrez_Gene (NCBI)PSMG4  389362  proteasome assembly chaperone 4
AliasesC6orf86; PAC4; bA506K6.2
GeneCards (Weizmann)PSMG4
Ensembl hg19 (Hinxton)ENSG00000180822 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000180822 [Gene_View]  ENSG00000180822 [Sequence]  chr6:3258928-3268066 [Contig_View]  PSMG4 [Vega]
ICGC DataPortalENSG00000180822
TCGA cBioPortalPSMG4
AceView (NCBI)PSMG4
Genatlas (Paris)PSMG4
WikiGenes389362
SOURCE (Princeton)PSMG4
Genetics Home Reference (NIH)PSMG4
Genomic and cartography
GoldenPath hg38 (UCSC)PSMG4  -     chr6:3258928-3268066 +  6p25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSMG4  -     6p25.2   [Description]    (hg19-Feb_2009)
EnsemblPSMG4 - 6p25.2 [CytoView hg19]  PSMG4 - 6p25.2 [CytoView hg38]
Mapping of homologs : NCBIPSMG4 [Mapview hg19]  PSMG4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA948231 AK092793 AK095683 AK096543 AK125314
RefSeq transcript (Entrez)NM_001128591 NM_001128592 NM_001135750
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSMG4
Cluster EST : UnigeneHs.731726 [ NCBI ]
CGAP (NCI)Hs.731726
Alternative Splicing GalleryENSG00000180822
Gene ExpressionPSMG4 [ NCBI-GEO ]   PSMG4 [ EBI - ARRAY_EXPRESS ]   PSMG4 [ SEEK ]   PSMG4 [ MEM ]
Gene Expression Viewer (FireBrowse)PSMG4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)389362
GTEX Portal (Tissue expression)PSMG4
Human Protein AtlasENSG00000180822-PSMG4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JS54   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JS54  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JS54
Splice isoforms : SwissVarQ5JS54
PhosPhoSitePlusQ5JS54
Domains : Interpro (EBI)PAC4   
Domain families : Pfam (Sanger)PAC4 (PF16093)   
Domain families : Pfam (NCBI)pfam16093   
Conserved Domain (NCBI)PSMG4
DMDM Disease mutations389362
Blocks (Seattle)PSMG4
SuperfamilyQ5JS54
Human Protein Atlas [tissue]ENSG00000180822-PSMG4 [tissue]
Peptide AtlasQ5JS54
IPIIPI00895892   IPI01009941   IPI00977782   IPI00641412   IPI00552237   IPI00552375   IPI00896469   IPI00965566   IPI00967439   IPI00966081   IPI00964871   
Protein Interaction databases
DIP (DOE-UCLA)Q5JS54
IntAct (EBI)Q5JS54
FunCoupENSG00000180822
BioGRIDPSMG4
STRING (EMBL)PSMG4
ZODIACPSMG4
Ontologies - Pathways
QuickGOQ5JS54
Ontology : AmiGOproteasome assembly  
Ontology : EGO-EBIproteasome assembly  
NDEx NetworkPSMG4
Atlas of Cancer Signalling NetworkPSMG4
Wikipedia pathwaysPSMG4
Orthology - Evolution
OrthoDB389362
GeneTree (enSembl)ENSG00000180822
Phylogenetic Trees/Animal Genes : TreeFamPSMG4
HOVERGENQ5JS54
HOGENOMQ5JS54
Homologs : HomoloGenePSMG4
Homology/Alignments : Family Browser (UCSC)PSMG4
Gene fusions - Rearrangements
Fusion : QuiverPSMG4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSMG4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSMG4
dbVarPSMG4
ClinVarPSMG4
1000_GenomesPSMG4 
Exome Variant ServerPSMG4
ExAC (Exome Aggregation Consortium)ENSG00000180822
GNOMAD BrowserENSG00000180822
Varsome BrowserPSMG4
Genetic variants : HAPMAP389362
Genomic Variants (DGV)PSMG4 [DGVbeta]
DECIPHERPSMG4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSMG4 
Mutations
ICGC Data PortalPSMG4 
TCGA Data PortalPSMG4 
Broad Tumor PortalPSMG4
OASIS PortalPSMG4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSMG4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSMG4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSMG4
DgiDB (Drug Gene Interaction Database)PSMG4
DoCM (Curated mutations)PSMG4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSMG4 (select a term)
intoGenPSMG4
Cancer3DPSMG4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETPSMG4
MedgenPSMG4
Genetic Testing Registry PSMG4
NextProtQ5JS54 [Medical]
TSGene389362
GENETestsPSMG4
Target ValidationPSMG4
Huge Navigator PSMG4 [HugePedia]
snp3D : Map Gene to Disease389362
BioCentury BCIQPSMG4
ClinGenPSMG4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD389362
Chemical/Pharm GKB GenePA162400256
Clinical trialPSMG4
Miscellaneous
canSAR (ICR)PSMG4 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSMG4
EVEXPSMG4
GoPubMedPSMG4
iHOPPSMG4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 14:25:33 CEST 2018

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