| DLEU2 (13q14.2) / PSPC1 (13q12.11) | PSPC1 (13q12.11) / ARHGEF2 (1q22) | PSPC1 (13q12.11) / CRYL1 (13q12.11) |
|
PSPC1 (13q12.11) / ENKUR (10p12.1) | PSPC1 (13q12.11) / LATS2 (13q12.11) | PSPC1 (13q12.11) / MPHOSPH8 (13q12.11) |
|
PSPC1 (13q12.11) / ZMYM5 (13q12.11) | VPS13C (15q22.2) / PSPC1 (13q12.11) | PSPC1 13q12.11 / ARHGEF2 1q22 |
|
PSPC1 13q12.11 / CRYL1 13q12.11 | PSPC1 13q12.11 / MPHOSPH8 13q12.11 | PSPC1 13q12.11 / ZMYM5 13q12.11 |
|
| Nomenclature |
HGNC (Hugo) | PSPC1 20320 |
| Cards |
Entrez_Gene (NCBI) | PSPC1 paraspeckle component 1 |
Aliases | PSP1 |
GeneCards (Weizmann) | PSPC1 |
Ensembl hg19 (Hinxton) | ENSG00000121390 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000121390 [Gene_View]  ENSG00000121390 [Sequence] chr13:19674752-19782945 [Contig_View] PSPC1 [Vega] |
ICGC DataPortal | ENSG00000121390 |
TCGA cBioPortal | PSPC1 |
AceView (NCBI) | PSPC1 |
Genatlas (Paris) | PSPC1 |
SOURCE (Princeton) | PSPC1 |
Genetics Home Reference (NIH) | PSPC1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | PSPC1 - chr13:19674752-19782945 - 13q12.11 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | PSPC1 - 13q12.11 [Description] (hg19-Feb_2009) |
GoldenPath | PSPC1 - 13q12.11 [CytoView hg19] PSPC1 - 13q12.11 [CytoView hg38] |
ImmunoBase | ENSG00000121390 |
genome Data Viewer NCBI | PSPC1 [Mapview hg19] |
OMIM | 612408 |
| Gene and transcription |
Genbank (Entrez) | AF448795 AF449627 AK001817 AK090873 AK301554 |
RefSeq transcript (Entrez) | NM_001042414 NM_001354908 NM_001354909 NM_001363660 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | PSPC1 |
Alternative Splicing Gallery | ENSG00000121390 |
Gene Expression | PSPC1 [ NCBI-GEO ] PSPC1 [ EBI - ARRAY_EXPRESS ]
PSPC1 [ SEEK ] PSPC1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | PSPC1 [ Firebrowse - Broad ] |
Genevisible | Expression of PSPC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 55269 |
GTEX Portal (Tissue expression) | PSPC1 |
Human Protein Atlas | ENSG00000121390-PSPC1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q8WXF1 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q8WXF1 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q8WXF1 |
Splice isoforms : SwissVar | Q8WXF1 |
PhosPhoSitePlus | Q8WXF1 |
Domaine pattern : Prosite (Expaxy) | RRM (PS50102) |
Domains : Interpro (EBI) | NOPS Nucleotide-bd_a/b_plait_sf PSP1_RRM1 PSP1_RRM2 RBD_domain_sf RRM_dom |
Domain families : Pfam (Sanger) | NOPS (PF08075) RRM_1 (PF00076) |
Domain families : Pfam (NCBI) | pfam08075 pfam00076 |
Domain families : Smart (EMBL) | RRM (SM00360) |
Conserved Domain (NCBI) | PSPC1 |
Blocks (Seattle) | PSPC1 |
PDB (RSDB) | 3SDE 5IFN 5WPA |
PDB Europe | 3SDE 5IFN 5WPA |
PDB (PDBSum) | 3SDE 5IFN 5WPA |
PDB (IMB) | 3SDE 5IFN 5WPA |
Structural Biology KnowledgeBase | 3SDE 5IFN 5WPA |
SCOP (Structural Classification of Proteins) | 3SDE 5IFN 5WPA |
CATH (Classification of proteins structures) | 3SDE 5IFN 5WPA |
Superfamily | Q8WXF1 |
Human Protein Atlas [tissue] | ENSG00000121390-PSPC1 [tissue] |
Peptide Atlas | Q8WXF1 |
HPRD | 10172 |
IPI | IPI00103525 IPI00395775 IPI01014916 IPI01009339 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q8WXF1 |
IntAct (EBI) | Q8WXF1 |
BioGRID | PSPC1 |
STRING (EMBL) | PSPC1 |
ZODIAC | PSPC1 |
| Ontologies - Pathways |
QuickGO | Q8WXF1 |
Ontology : AmiGO | mRNA splicing, via spliceosome transcription regulatory region sequence-specific DNA binding fibrillar center activation of innate immune response nucleic acid binding RNA binding protein binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated nuclear matrix nuclear speck paraspeckles regulation of circadian rhythm innate immune response negative regulation of transcription, DNA-templated rhythmic process E-box binding |
Ontology : EGO-EBI | mRNA splicing, via spliceosome transcription regulatory region sequence-specific DNA binding fibrillar center activation of innate immune response nucleic acid binding RNA binding protein binding nucleus nucleoplasm cytoplasm regulation of transcription, DNA-templated nuclear matrix nuclear speck paraspeckles regulation of circadian rhythm innate immune response negative regulation of transcription, DNA-templated rhythmic process E-box binding |
NDEx Network | PSPC1 |
Atlas of Cancer Signalling Network | PSPC1 |
Wikipedia pathways | PSPC1 |
| Orthology - Evolution |
OrthoDB | 55269 |
GeneTree (enSembl) | ENSG00000121390 |
Phylogenetic Trees/Animal Genes : TreeFam | PSPC1 |
HOGENOM | Q8WXF1 |
Homologs : HomoloGene | PSPC1 |
Homology/Alignments : Family Browser (UCSC) | PSPC1 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | DLEU2/PSPC1 [13q14.2/13q12.11]   |
Fusion : Mitelman | PSPC1/ARHGEF2 [13q12.11/1q22]   |
Fusion : Mitelman | PSPC1/CRYL1 [13q12.11/13q12.11]   |
Fusion : Mitelman | PSPC1/MPHOSPH8 [13q12.11/13q12.11]   |
Fusion : Mitelman | PSPC1/ZMYM5 [13q12.11/13q12.11]   |
Fusion Portal | PSPC1 13q12.11 ARHGEF2 1q22 BRCA |
Fusion Portal | PSPC1 13q12.11 CRYL1 13q12.11 GBM |
Fusion Portal | PSPC1 13q12.11 MPHOSPH8 13q12.11 BLCA |
Fusion Portal | PSPC1 13q12.11 ZMYM5 13q12.11 BRCA |
Fusion : Quiver | PSPC1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | PSPC1 [hg38] |
dbVar | PSPC1 |
ClinVar | PSPC1 |
Monarch | PSPC1 |
1000_Genomes | PSPC1 |
Exome Variant Server | PSPC1 |
GNOMAD Browser | ENSG00000121390 |
Varsome Browser | PSPC1 |
Genomic Variants (DGV) | PSPC1 [DGVbeta] |
DECIPHER | PSPC1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | PSPC1 |
| Mutations |
ICGC Data Portal | PSPC1 |
TCGA Data Portal | PSPC1 |
Broad Tumor Portal | PSPC1 |
OASIS Portal | PSPC1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | PSPC1 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | PSPC1 |
Mutations and Diseases : HGMD | PSPC1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search PSPC1 |
DgiDB (Drug Gene Interaction Database) | PSPC1 |
DoCM (Curated mutations) | PSPC1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | PSPC1 (select a term) |
intoGen | PSPC1 |
Cancer3D | PSPC1(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 612408 |
Orphanet | |
DisGeNET | PSPC1 |
Medgen | PSPC1 |
Genetic Testing Registry | PSPC1
|
NextProt | Q8WXF1 [Medical] |
GENETests | PSPC1 |
Target Validation | PSPC1 |
Huge Navigator |
PSPC1 [HugePedia] |
ClinGen | PSPC1 |
| Clinical trials, drugs, therapy |
---|
MyCancerGenome | PSPC1 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA134968603 |
Pharos | Q8WXF1 |
Clinical trial | PSPC1 |
| Miscellaneous |
---|
canSAR (ICR) | PSPC1 (select the gene name) |
Harmonizome | PSPC1 |
DataMed Index | PSPC1 |
| Probes |
---|
| Litterature |
---|
PubMed | 88 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | PSPC1 |