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PSPH (phosphoserine phosphatase)

Identity

Other namesPSP
PSPHD
HGNC (Hugo) PSPH
LocusID (NCBI) 5723
Location 7p11.2
Location_base_pair Starts at 56078744 and ends at 56119268 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)PSPH   9577
Entrez_Gene (NCBI)PSPH  5723  phosphoserine phosphatase
Cards
GeneCards (Weizmann)PSPH
Ensembl (Hinxton)ENSG00000146733 [Gene_View]  chr7:56078744-56119268 [Contig_View]  PSPH [Vega]
AceView (NCBI)PSPH
Genatlas (Paris)PSPH
SOURCE (Stanford)NM_004577
Genomic and cartography
GoldenPath (UCSC)PSPH  -  7p11.2   chr7:56078744-56119268 -  7p11.2   [Description]    (hg19-Feb_2009)
EnsemblPSPH - 7p11.2 [CytoView]
Mapping of homologs : NCBIPSPH [Mapview]
OMIM172480   614023   
Gene and transcription
Genbank (Entrez)AK054677 AK126156 AK223508 AK315235 AW574794
RefSeq transcript (SRS)NM_004577
RefSeq transcript (Entrez)NM_004577
RefSeq genomic (SRS)AC_000068 AC_000139 NC_000007 NC_018918 NG_011473 NT_033968 NT_079592 NW_001839010 NW_004078029
RefSeq genomic (Entrez)AC_000068 AC_000139 NC_000007 NC_018918 NG_011473 NT_033968 NT_079592 NW_001839010 NW_004078029
Consensus coding sequences : CCDS (NCBI)PSPH
Cluster EST : UnigeneHs.512656 [ SRS ] Hs.512656 [ NCBI ]
CGAP (NCI)Hs.512656
Alternative Splicing : Fast-db (Paris)GSHG0028213
Alternative Splicing GalleryENSG00000146733
Gene ExpressionPSPH [ NCBI-GEO ]   PSPH [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78330 (SRS) P78330 (Uniprot)
NextProtP78330
With graphics : InterProP78330
Splice isoforms : SwissVarP78330(Swissvar)
Domains : Interpro (SRS)Dehalogen-like_hydro    HAD-like_dom    HAD-SF_hydro_IB_PSP-like    Pser_Pase_dom_2    SerB   
Domains : Interpro (EBI)Dehalogen-like_hydro    HAD-like_dom    HAD-SF_hydro_IB_PSP-like    Pser_Pase_dom_2    SerB   
Related proteins : CluSTrP78330
Domain families : Pfam (SRS)Hydrolase (PF00702)   
Domain families : Pfam (Sanger)Hydrolase (PF00702)   
Domain families : Pfam (NCBI)pfam00702   
DMDM5723
Blocks (Seattle)P78330
PDB (SRS)1L8L    1L8O    1NNL   
PDB (PDBSum)1L8L    1L8O    1NNL   
PDB (IMB)1L8L    1L8O    1NNL   
PDB (RSDB)1L8L    1L8O    1NNL   
Human Protein AtlasENSG00000146733
HPRD01406
IPIIPI00019178   IPI00927730   IPI00925737   IPI00925485   IPI00925131   
Protein Interaction databases
DIP (DOE-UCLA)P78330
IntAct (EBI)P78330
FunCoupENSG00000146733
REACTOMEPSPH
Protein Interaction Database5723
BioGRIDPSPH
InParanoidP78330
Interologous Interaction database P78330
IntegromeDBPSPH
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PSPH
SNP (GeneSNP Utah)PSPH
SNP : HGBasePSPH
Genetic variants : HAPMAPPSPH
Somatic Mutations in Cancer : COSMICPSPH 
CONAN: Copy Number AnalysisPSPH 
Mutations and Diseases : HGMDPSPH
OMIM172480    614023   
GENETests172480    614023   
Disease Genetic AssociationPSPH
Huge Navigator PSPH [HugePedia]  PSPH [HugeCancerGEM]
Genomic VariantsPSPH  PSPH [DGVbeta]
snp3D : Map Gene to Disease5723
General knowledge
Homologs : HomoloGenePSPH
Homology/Alignments : Family Browser (UCSC)PSPH
Phylogenetic Trees/Animal Genes : TreeFamPSPH
Catalytic activity : Enzyme3.1.3.3 [ Enzyme-Expasy ]   3.1.3.3 [ Enzyme-SRS ]   3.1.3.3 [ IntEnz-EBI ]   3.1.3.3 [ BRENDA ]   3.1.3.3 [ KEGG ]   
Chemical/Protein Interactions : CTD5723
Chemical/Pharm GKB GenePA33928
Clinical trialPSPH
Cancer Resource (Charite)ENSG00000146733
Ontology : AmiGOmagnesium ion binding  phosphoserine phosphatase activity  phosphoserine phosphatase activity  calcium ion binding  cytoplasm  cytosol  L-serine metabolic process  L-serine biosynthetic process  L-serine biosynthetic process  cellular amino acid biosynthetic process  response to mechanical stimulus  response to nutrient levels  response to testosterone stimulus  cellular nitrogen compound metabolic process  protein homodimerization activity  small molecule metabolic process  
Ontology : EGO-EBImagnesium ion binding  phosphoserine phosphatase activity  phosphoserine phosphatase activity  calcium ion binding  cytoplasm  cytosol  L-serine metabolic process  L-serine biosynthetic process  L-serine biosynthetic process  cellular amino acid biosynthetic process  response to mechanical stimulus  response to nutrient levels  response to testosterone stimulus  cellular nitrogen compound metabolic process  protein homodimerization activity  small molecule metabolic process  
Pathways : KEGGGlycine, serine and threonine metabolism
Other databases
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
PubGenePSPH
iHOPPSPH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:43:44 CEST 2013
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