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PSPN (persephin)

Identity

Alias_symbol (synonym)PSP
Other alias
HGNC (Hugo) PSPN
LocusID (NCBI) 5623
Atlas_Id 55497
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 6375148 and ends at 6375916 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GTF2F1 (19p13.3) / PSPN (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSPN   9579
Cards
Entrez_Gene (NCBI)PSPN  5623  persephin
AliasesPSP
GeneCards (Weizmann)PSPN
Ensembl hg19 (Hinxton)ENSG00000125650 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125650 [Gene_View]  chr19:6375148-6375916 [Contig_View]  PSPN [Vega]
ICGC DataPortalENSG00000125650
TCGA cBioPortalPSPN
AceView (NCBI)PSPN
Genatlas (Paris)PSPN
WikiGenes5623
SOURCE (Princeton)PSPN
Genetics Home Reference (NIH)PSPN
Genomic and cartography
GoldenPath hg38 (UCSC)PSPN  -     chr19:6375148-6375916 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSPN  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblPSPN - 19p13.3 [CytoView hg19]  PSPN - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIPSPN [Mapview hg19]  PSPN [Mapview hg38]
OMIM602921   
Gene and transcription
Genbank (Entrez)AF040962 AK055490 BC143894 BC152717 BC156563
RefSeq transcript (Entrez)NM_004158
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSPN
Cluster EST : UnigeneHs.248159 [ NCBI ]
CGAP (NCI)Hs.248159
Alternative Splicing GalleryENSG00000125650
Gene ExpressionPSPN [ NCBI-GEO ]   PSPN [ EBI - ARRAY_EXPRESS ]   PSPN [ SEEK ]   PSPN [ MEM ]
Gene Expression Viewer (FireBrowse)PSPN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5623
GTEX Portal (Tissue expression)PSPN
Human Protein AtlasENSG00000125650-PSPN [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60542   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60542  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60542
Splice isoforms : SwissVarO60542
PhosPhoSitePlusO60542
Domaine pattern : Prosite (Expaxy)TGF_BETA_2 (PS51362)   
Domains : Interpro (EBI)Cystine-knot_cytokine    TGF-b_C   
Domain families : Pfam (Sanger)TGF_beta (PF00019)   
Domain families : Pfam (NCBI)pfam00019   
Domain families : Smart (EMBL)TGFB (SM00204)  
Conserved Domain (NCBI)PSPN
DMDM Disease mutations5623
Blocks (Seattle)PSPN
SuperfamilyO60542
Human Protein Atlas [tissue]ENSG00000125650-PSPN [tissue]
Peptide AtlasO60542
HPRD04230
IPIIPI01010579   IPI01010482   
Protein Interaction databases
DIP (DOE-UCLA)O60542
IntAct (EBI)O60542
FunCoupENSG00000125650
BioGRIDPSPN
STRING (EMBL)PSPN
ZODIACPSPN
Ontologies - Pathways
QuickGOO60542
Ontology : AmiGOMAPK cascade  Ras guanyl-nucleotide exchange factor activity  receptor binding  extracellular region  intracellular  nervous system development  axon guidance  central nervous system development  growth factor activity  positive regulation of GTPase activity  
Ontology : EGO-EBIMAPK cascade  Ras guanyl-nucleotide exchange factor activity  receptor binding  extracellular region  intracellular  nervous system development  axon guidance  central nervous system development  growth factor activity  positive regulation of GTPase activity  
NDEx NetworkPSPN
Atlas of Cancer Signalling NetworkPSPN
Wikipedia pathwaysPSPN
Orthology - Evolution
OrthoDB5623
GeneTree (enSembl)ENSG00000125650
Phylogenetic Trees/Animal Genes : TreeFamPSPN
HOVERGENO60542
HOGENOMO60542
Homologs : HomoloGenePSPN
Homology/Alignments : Family Browser (UCSC)PSPN
Gene fusions - Rearrangements
Tumor Fusion PortalPSPN
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSPN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSPN
dbVarPSPN
ClinVarPSPN
1000_GenomesPSPN 
Exome Variant ServerPSPN
ExAC (Exome Aggregation Consortium)ENSG00000125650
GNOMAD BrowserENSG00000125650
Genetic variants : HAPMAP5623
Genomic Variants (DGV)PSPN [DGVbeta]
DECIPHERPSPN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSPN 
Mutations
ICGC Data PortalPSPN 
TCGA Data PortalPSPN 
Broad Tumor PortalPSPN
OASIS PortalPSPN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSPN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSPN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSPN
DgiDB (Drug Gene Interaction Database)PSPN
DoCM (Curated mutations)PSPN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSPN (select a term)
intoGenPSPN
Cancer3DPSPN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602921   
Orphanet
DisGeNETPSPN
MedgenPSPN
Genetic Testing Registry PSPN
NextProtO60542 [Medical]
TSGene5623
GENETestsPSPN
Target ValidationPSPN
Huge Navigator PSPN [HugePedia]
snp3D : Map Gene to Disease5623
BioCentury BCIQPSPN
ClinGenPSPN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5623
Chemical/Pharm GKB GenePA33930
Clinical trialPSPN
Miscellaneous
canSAR (ICR)PSPN (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSPN
EVEXPSPN
GoPubMedPSPN
iHOPPSPN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:30:50 CET 2017

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