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PSRC1 (proline and serine rich coiled-coil 1)

Identity

Alias_namesproline/serine-rich coiled-coil 1
Alias_symbol (synonym)DDA3
Other aliasFP3214
HGNC (Hugo) PSRC1
LocusID (NCBI) 84722
Atlas_Id 40277
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 109279554 and ends at 109283168 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MB (22q12.3) / PSRC1 (1p13.3)PSRC1 (1p13.3) / MYBPHL (1p13.3)PSRC1 (1p13.3) / PSRC1 (1p13.3)
PSRC1 1p13.3 / MYBPHL 1p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PSRC1   24472
Cards
Entrez_Gene (NCBI)PSRC1  84722  proline and serine rich coiled-coil 1
AliasesDDA3; FP3214
GeneCards (Weizmann)PSRC1
Ensembl hg19 (Hinxton)ENSG00000134222 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134222 [Gene_View]  chr1:109279554-109283168 [Contig_View]  PSRC1 [Vega]
ICGC DataPortalENSG00000134222
TCGA cBioPortalPSRC1
AceView (NCBI)PSRC1
Genatlas (Paris)PSRC1
WikiGenes84722
SOURCE (Princeton)PSRC1
Genetics Home Reference (NIH)PSRC1
Genomic and cartography
GoldenPath hg38 (UCSC)PSRC1  -     chr1:109279554-109283168 -  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSRC1  -     1p13.3   [Description]    (hg19-Feb_2009)
EnsemblPSRC1 - 1p13.3 [CytoView hg19]  PSRC1 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIPSRC1 [Mapview hg19]  PSRC1 [Mapview hg38]
OMIM613126   
Gene and transcription
Genbank (Entrez)AF223000 AF447874 AK126567 AK289593 AW898470
RefSeq transcript (Entrez)NM_001005290 NM_001032290 NM_001032291 NM_001350237 NM_001350238 NM_001350239 NM_001350240 NM_001350241 NM_001350242 NM_032636
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PSRC1
Cluster EST : UnigeneHs.405925 [ NCBI ]
CGAP (NCI)Hs.405925
Alternative Splicing GalleryENSG00000134222
Gene ExpressionPSRC1 [ NCBI-GEO ]   PSRC1 [ EBI - ARRAY_EXPRESS ]   PSRC1 [ SEEK ]   PSRC1 [ MEM ]
Gene Expression Viewer (FireBrowse)PSRC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84722
GTEX Portal (Tissue expression)PSRC1
Human Protein AtlasENSG00000134222-PSRC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PGN9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PGN9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PGN9
Splice isoforms : SwissVarQ6PGN9
PhosPhoSitePlusQ6PGN9
Domains : Interpro (EBI)DDA3    DDA3/GTSE-1    GTSE1_N   
Domain families : Pfam (Sanger)GTSE1_N (PF15259)   
Domain families : Pfam (NCBI)pfam15259   
Conserved Domain (NCBI)PSRC1
DMDM Disease mutations84722
Blocks (Seattle)PSRC1
SuperfamilyQ6PGN9
Human Protein Atlas [tissue]ENSG00000134222-PSRC1 [tissue]
Peptide AtlasQ6PGN9
HPRD13127
IPIIPI00448173   IPI00027963   IPI00445113   IPI00828052   IPI00642539   IPI00871914   
Protein Interaction databases
DIP (DOE-UCLA)Q6PGN9
IntAct (EBI)Q6PGN9
FunCoupENSG00000134222
BioGRIDPSRC1
STRING (EMBL)PSRC1
ZODIACPSRC1
Ontologies - Pathways
QuickGOQ6PGN9
Ontology : AmiGOspindle pole  microtubule bundle formation  protein binding  nucleoplasm  cytoplasm  spindle  cytosol  spindle microtubule  mitotic metaphase plate congression  microtubule binding  microtubule cytoskeleton  negative regulation of cell growth  midbody  positive regulation of microtubule polymerization  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription, DNA-templated  cell division  regulation of mitotic spindle organization  
Ontology : EGO-EBIspindle pole  microtubule bundle formation  protein binding  nucleoplasm  cytoplasm  spindle  cytosol  spindle microtubule  mitotic metaphase plate congression  microtubule binding  microtubule cytoskeleton  negative regulation of cell growth  midbody  positive regulation of microtubule polymerization  positive regulation of cyclin-dependent protein serine/threonine kinase activity  positive regulation of transcription, DNA-templated  cell division  regulation of mitotic spindle organization  
NDEx NetworkPSRC1
Atlas of Cancer Signalling NetworkPSRC1
Wikipedia pathwaysPSRC1
Orthology - Evolution
OrthoDB84722
GeneTree (enSembl)ENSG00000134222
Phylogenetic Trees/Animal Genes : TreeFamPSRC1
HOVERGENQ6PGN9
HOGENOMQ6PGN9
Homologs : HomoloGenePSRC1
Homology/Alignments : Family Browser (UCSC)PSRC1
Gene fusions - Rearrangements
Fusion : MitelmanPSRC1/MYBPHL [1p13.3/1p13.3]  
Fusion: TCGA_MDACCPSRC1 1p13.3 MYBPHL 1p13.3 OV
Tumor Fusion PortalPSRC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSRC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSRC1
dbVarPSRC1
ClinVarPSRC1
1000_GenomesPSRC1 
Exome Variant ServerPSRC1
ExAC (Exome Aggregation Consortium)ENSG00000134222
GNOMAD BrowserENSG00000134222
Genetic variants : HAPMAP84722
Genomic Variants (DGV)PSRC1 [DGVbeta]
DECIPHERPSRC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSRC1 
Mutations
ICGC Data PortalPSRC1 
TCGA Data PortalPSRC1 
Broad Tumor PortalPSRC1
OASIS PortalPSRC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSRC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPSRC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PSRC1
DgiDB (Drug Gene Interaction Database)PSRC1
DoCM (Curated mutations)PSRC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PSRC1 (select a term)
intoGenPSRC1
Cancer3DPSRC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613126   
Orphanet
DisGeNETPSRC1
MedgenPSRC1
Genetic Testing Registry PSRC1
NextProtQ6PGN9 [Medical]
TSGene84722
GENETestsPSRC1
Target ValidationPSRC1
Huge Navigator PSRC1 [HugePedia]
snp3D : Map Gene to Disease84722
BioCentury BCIQPSRC1
ClinGenPSRC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84722
Chemical/Pharm GKB GenePA142671120
Clinical trialPSRC1
Miscellaneous
canSAR (ICR)PSRC1 (select the gene name)
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePSRC1
EVEXPSRC1
GoPubMedPSRC1
iHOPPSRC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:30:50 CET 2017

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