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PSTK (phosphoseryl-tRNA kinase)

Identity

Alias (NCBI)C10orf89
HGNC (Hugo) PSTK
HGNC Alias symbMGC35392
HGNC Alias nameL-seryl-tRNA(Sec) kinase
 O-phosphoseryl-tRNA(Sec) kinase
HGNC Previous nameC10orf89
HGNC Previous namechromosome 10 open reading frame 89
LocusID (NCBI) 118672
Atlas_Id 72363
Location 10q26.13  [Link to chromosome band 10q26]
Location_base_pair Starts at 122980401 and ends at 122990390 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C10orf88 (10q26.13) / PSTK (10q26.13)PSTK (10q26.13) / SLCO1A2 (12p12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PSTK   28578
Cards
Entrez_Gene (NCBI)PSTK    phosphoseryl-tRNA kinase
AliasesC10orf89
GeneCards (Weizmann)PSTK
Ensembl hg19 (Hinxton)ENSG00000179988 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000179988 [Gene_View]  ENSG00000179988 [Sequence]  chr10:122980401-122990390 [Contig_View]  PSTK [Vega]
ICGC DataPortalENSG00000179988
TCGA cBioPortalPSTK
AceView (NCBI)PSTK
Genatlas (Paris)PSTK
SOURCE (Princeton)PSTK
Genetics Home Reference (NIH)PSTK
Genomic and cartography
GoldenPath hg38 (UCSC)PSTK  -     chr10:122980401-122990390 +  10q26.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PSTK  -     10q26.13   [Description]    (hg19-Feb_2009)
GoldenPathPSTK - 10q26.13 [CytoView hg19]  PSTK - 10q26.13 [CytoView hg38]
ImmunoBaseENSG00000179988
Genome Data Viewer NCBIPSTK [Mapview hg19]  
OMIM611310   
Gene and transcription
Genbank (Entrez)AK094271 AK127173 AL833506 BC035344
RefSeq transcript (Entrez)NM_001363531 NM_153336
Consensus coding sequences : CCDS (NCBI)PSTK
Gene ExpressionPSTK [ NCBI-GEO ]   PSTK [ EBI - ARRAY_EXPRESS ]   PSTK [ SEEK ]   PSTK [ MEM ]
Gene Expression Viewer (FireBrowse)PSTK [ Firebrowse - Broad ]
GenevisibleExpression of PSTK in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)118672
GTEX Portal (Tissue expression)PSTK
Human Protein AtlasENSG00000179988-PSTK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IV42   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IV42  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IV42
Catalytic activity : Enzyme2.7.1.164 [ Enzyme-Expasy ]   2.7.1.1642.7.1.164 [ IntEnz-EBI ]   2.7.1.164 [ BRENDA ]   2.7.1.164 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ8IV42
Domains : Interpro (EBI)KTI12/PSTK    L-seryl-tRNA_Sec_kinase_euk    P-loop_NTPase   
Domain families : Pfam (Sanger)KTI12 (PF08433)   
Domain families : Pfam (NCBI)pfam08433   
Conserved Domain (NCBI)PSTK
SuperfamilyQ8IV42
AlphaFold pdb e-kbQ8IV42   
Human Protein Atlas [tissue]ENSG00000179988-PSTK [tissue]
HPRD16586
Protein Interaction databases
DIP (DOE-UCLA)Q8IV42
IntAct (EBI)Q8IV42
BioGRIDPSTK
STRING (EMBL)PSTK
ZODIACPSTK
Ontologies - Pathways
QuickGOQ8IV42
Ontology : AmiGOtRNA binding  ATP binding  translation  kinase activity  phosphorylation  L-seryl-tRNA(Sec) kinase activity  selenocysteinyl-tRNA(Sec) biosynthetic process  
Ontology : EGO-EBItRNA binding  ATP binding  translation  kinase activity  phosphorylation  L-seryl-tRNA(Sec) kinase activity  selenocysteinyl-tRNA(Sec) biosynthetic process  
NDEx NetworkPSTK
Atlas of Cancer Signalling NetworkPSTK
Wikipedia pathwaysPSTK
Orthology - Evolution
OrthoDB118672
GeneTree (enSembl)ENSG00000179988
Phylogenetic Trees/Animal Genes : TreeFamPSTK
Homologs : HomoloGenePSTK
Homology/Alignments : Family Browser (UCSC)PSTK
Gene fusions - Rearrangements
Fusion : QuiverPSTK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPSTK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PSTK
dbVarPSTK
ClinVarPSTK
MonarchPSTK
1000_GenomesPSTK 
Exome Variant ServerPSTK
GNOMAD BrowserENSG00000179988
Varsome BrowserPSTK
ACMGPSTK variants
VarityQ8IV42
Genomic Variants (DGV)PSTK [DGVbeta]
DECIPHERPSTK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPSTK 
Mutations
ICGC Data PortalPSTK 
TCGA Data PortalPSTK 
Broad Tumor PortalPSTK
OASIS PortalPSTK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPSTK  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPSTK
Mutations and Diseases : HGMDPSTK
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPSTK
DgiDB (Drug Gene Interaction Database)PSTK
DoCM (Curated mutations)PSTK
CIViC (Clinical Interpretations of Variants in Cancer)PSTK
Cancer3DPSTK
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611310   
Orphanet
DisGeNETPSTK
MedgenPSTK
Genetic Testing Registry PSTK
NextProtQ8IV42 [Medical]
GENETestsPSTK
Target ValidationPSTK
Huge Navigator PSTK [HugePedia]
ClinGenPSTK
Clinical trials, drugs, therapy
MyCancerGenomePSTK
Protein Interactions : CTDPSTK
Pharm GKB GenePA162400268
PharosQ8IV42
Clinical trialPSTK
Miscellaneous
canSAR (ICR)PSTK
HarmonizomePSTK
DataMed IndexPSTK
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPSTK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:17:34 CEST 2021

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