PTBP3 (polypyrimidine tract binding protein 3)

2009-08-01  

Identity

HGNC
LOCATION
9q32
LOCUSID
ALIAS
ROD1
FUSION GENES

Other Information

Locus ID:

NCBI: 9991
MIM: 607527
HGNC: 10253
Ensembl: ENSG00000119314

Variants:

dbSNP: 9991
ClinVar: 9991
TCGA: ENSG00000119314
COSMIC: PTBP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119314ENST00000210227X6R242
ENSG00000119314ENST00000334318O95758
ENSG00000119314ENST00000343327O95758
ENSG00000119314ENST00000374255O95758
ENSG00000119314ENST00000374255A0A024R163
ENSG00000119314ENST00000374257O95758
ENSG00000119314ENST00000450374B1ALY4
ENSG00000119314ENST00000458258O95758

Expression (GTEx)

0
10
20
30
40
50
60
70

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
291874062018PTBP3-Mediated Regulation of ZEB1 mRNA Stability Promotes Epithelial-Mesenchymal Transition in Breast Cancer.21
230247542012ROD1 is a seedless target gene of hypoxia-induced miR-210.18
225756432012A new function of ROD1 in nonsense-mediated mRNA decay.15
300689402018PTBP3 splicing factor promotes hepatocellular carcinoma by destroying the splicing balance of NEAT1 and pre-miR-612.14
282220702017Inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells.12
264433142015MicroRNA-210 regulates cell proliferation and apoptosis by targeting regulator of differentiation 1 in glioblastoma cells.11
194410792009Regulator of differentiation 1 (ROD1) binds to the amphipathic C-terminal peptide of thrombospondin-4 and is involved in its mitogenic activity.9
297524412018PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing.9
251191032014The effects of PTBP3 silencing on the proliferation and differentiation of MKN45 human gastric cancer cells.6

Citation

Dessen P

PTBP3 (polypyrimidine tract binding protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2009-08-01

Online version: http://atlasgeneticsoncology.org/gene/51015/ptbp3