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PTDSS2 (phosphatidylserine synthase 2)

Identity

Alias_symbol (synonym)PSS2
Other alias
HGNC (Hugo) PTDSS2
LocusID (NCBI) 81490
Atlas_Id 72373
Location 11p15.5  [Link to chromosome band 11p15]
Location_base_pair Starts at 450280 and ends at 491400 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTDSS2   15463
Cards
Entrez_Gene (NCBI)PTDSS2  81490  phosphatidylserine synthase 2
AliasesPSS2
GeneCards (Weizmann)PTDSS2
Ensembl hg19 (Hinxton)ENSG00000174915 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174915 [Gene_View]  chr11:450280-491400 [Contig_View]  PTDSS2 [Vega]
ICGC DataPortalENSG00000174915
TCGA cBioPortalPTDSS2
AceView (NCBI)PTDSS2
Genatlas (Paris)PTDSS2
WikiGenes81490
SOURCE (Princeton)PTDSS2
Genetics Home Reference (NIH)PTDSS2
Genomic and cartography
GoldenPath hg38 (UCSC)PTDSS2  -     chr11:450280-491400 +  11p15.5   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PTDSS2  -     11p15.5   [Description]    (hg19-Feb_2009)
EnsemblPTDSS2 - 11p15.5 [CytoView hg19]  PTDSS2 - 11p15.5 [CytoView hg38]
Mapping of homologs : NCBIPTDSS2 [Mapview hg19]  PTDSS2 [Mapview hg38]
OMIM612793   
Gene and transcription
Genbank (Entrez)AK307374 AK311723 AL834357 BC001210 BC015702
RefSeq transcript (Entrez)NM_001329544 NM_001329545 NM_001329548 NM_030783
RefSeq genomic (Entrez)NC_000011 NC_018922 NT_187586
Consensus coding sequences : CCDS (NCBI)PTDSS2
Cluster EST : UnigeneHs.731700 [ NCBI ]
CGAP (NCI)Hs.731700
Alternative Splicing GalleryENSG00000174915
Gene ExpressionPTDSS2 [ NCBI-GEO ]   PTDSS2 [ EBI - ARRAY_EXPRESS ]   PTDSS2 [ SEEK ]   PTDSS2 [ MEM ]
Gene Expression Viewer (FireBrowse)PTDSS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)81490
GTEX Portal (Tissue expression)PTDSS2
Human Protein AtlasENSG00000174915-PTDSS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BVG9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BVG9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BVG9
Splice isoforms : SwissVarQ9BVG9
Catalytic activity : Enzyme2.7.8.29 [ Enzyme-Expasy ]   2.7.8.292.7.8.29 [ IntEnz-EBI ]   2.7.8.29 [ BRENDA ]   2.7.8.29 [ KEGG ]   
PhosPhoSitePlusQ9BVG9
Domains : Interpro (EBI)PSS   
Domain families : Pfam (Sanger)PSS (PF03034)   
Domain families : Pfam (NCBI)pfam03034   
Conserved Domain (NCBI)PTDSS2
DMDM Disease mutations81490
Blocks (Seattle)PTDSS2
SuperfamilyQ9BVG9
Human Protein Atlas [tissue]ENSG00000174915-PTDSS2 [tissue]
Peptide AtlasQ9BVG9
HPRD17927
IPIIPI00006538   IPI00978193   IPI00977742   
Protein Interaction databases
DIP (DOE-UCLA)Q9BVG9
IntAct (EBI)Q9BVG9
FunCoupENSG00000174915
BioGRIDPTDSS2
STRING (EMBL)PTDSS2
ZODIACPTDSS2
Ontologies - Pathways
QuickGOQ9BVG9
Ontology : AmiGOCDP-diacylglycerol-serine O-phosphatidyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  phosphatidylserine biosynthetic process  phosphatidylserine biosynthetic process  membrane  integral component of membrane  transferase activity  
Ontology : EGO-EBICDP-diacylglycerol-serine O-phosphatidyltransferase activity  endoplasmic reticulum membrane  endoplasmic reticulum membrane  phosphatidylserine biosynthetic process  phosphatidylserine biosynthetic process  membrane  integral component of membrane  transferase activity  
Pathways : KEGGGlycerophospholipid metabolism   
NDEx NetworkPTDSS2
Atlas of Cancer Signalling NetworkPTDSS2
Wikipedia pathwaysPTDSS2
Orthology - Evolution
OrthoDB81490
GeneTree (enSembl)ENSG00000174915
Phylogenetic Trees/Animal Genes : TreeFamPTDSS2
HOVERGENQ9BVG9
HOGENOMQ9BVG9
Homologs : HomoloGenePTDSS2
Homology/Alignments : Family Browser (UCSC)PTDSS2
Gene fusions - Rearrangements
Tumor Fusion PortalPTDSS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTDSS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTDSS2
dbVarPTDSS2
ClinVarPTDSS2
1000_GenomesPTDSS2 
Exome Variant ServerPTDSS2
ExAC (Exome Aggregation Consortium)ENSG00000174915
GNOMAD BrowserENSG00000174915
Genetic variants : HAPMAP81490
Genomic Variants (DGV)PTDSS2 [DGVbeta]
DECIPHERPTDSS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPTDSS2 
Mutations
ICGC Data PortalPTDSS2 
TCGA Data PortalPTDSS2 
Broad Tumor PortalPTDSS2
OASIS PortalPTDSS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTDSS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPTDSS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PTDSS2
DgiDB (Drug Gene Interaction Database)PTDSS2
DoCM (Curated mutations)PTDSS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTDSS2 (select a term)
intoGenPTDSS2
Cancer3DPTDSS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612793   
Orphanet
DisGeNETPTDSS2
MedgenPTDSS2
Genetic Testing Registry PTDSS2
NextProtQ9BVG9 [Medical]
TSGene81490
GENETestsPTDSS2
Target ValidationPTDSS2
Huge Navigator PTDSS2 [HugePedia]
snp3D : Map Gene to Disease81490
BioCentury BCIQPTDSS2
ClinGenPTDSS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD81490
Chemical/Pharm GKB GenePA33940
Clinical trialPTDSS2
Miscellaneous
canSAR (ICR)PTDSS2 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTDSS2
EVEXPTDSS2
GoPubMedPTDSS2
iHOPPTDSS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:08:49 CET 2017

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