| Nomenclature |
|---|
| HGNC (Hugo) | PTF1A 23734 |
| Cards |
|---|
| Entrez_Gene (NCBI) | PTF1A 256297 pancreas associated transcription factor 1a |
| Aliases | PACA; PAGEN2; PTF1-p48; bHLHa29; |
| p48 |
| GeneCards (Weizmann) | PTF1A |
| Ensembl hg19 (Hinxton) | ENSG00000168267 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000168267 [Gene_View] ENSG00000168267 [Sequence] chr10:23192531-23194252 [Contig_View] PTF1A [Vega] |
| ICGC DataPortal | ENSG00000168267 |
| TCGA cBioPortal | PTF1A |
| AceView (NCBI) | PTF1A |
| Genatlas (Paris) | PTF1A |
| WikiGenes | 256297 |
| SOURCE (Princeton) | PTF1A |
| Genetics Home Reference (NIH) | PTF1A |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | PTF1A - chr10:23192531-23194252 + 10p12.2 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | PTF1A - 10p12.2 [Description] (hg19-Feb_2009) |
PTF1A - 10p12.2 [CytoView hg19] PTF1A - 10p12.2 [CytoView hg38] |
| Mapping of homologs : NCBI | PTF1A [Mapview hg19] PTF1A [Mapview hg38] |
| OMIM | 607194 609069 615935 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF181999 BM055347 CK904916 |
| RefSeq transcript (Entrez) | NM_178161 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | PTF1A |
| Cluster EST : Unigene | Hs.351503 [ NCBI ] |
| CGAP (NCI) | Hs.351503 |
| Alternative Splicing Gallery | ENSG00000168267 |
| Gene Expression | PTF1A [ NCBI-GEO ] PTF1A [ EBI - ARRAY_EXPRESS ]
PTF1A [ SEEK ] PTF1A [ MEM ] |
| Gene Expression Viewer (FireBrowse) | PTF1A [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 256297 |
| GTEX Portal (Tissue expression) | PTF1A |
| Human Protein Atlas | ENSG00000168267-PTF1A [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q7RTS3 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q7RTS3 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q7RTS3 |
| Splice isoforms : SwissVar | Q7RTS3 |
| PhosPhoSitePlus | Q7RTS3 |
| Domaine pattern : Prosite (Expaxy) | BHLH (PS50888) |
| Domains : Interpro (EBI) | bHLH_dom HLH_DNA-bd_sf |
| Domain families : Pfam (Sanger) | HLH (PF00010) |
| Domain families : Pfam (NCBI) | pfam00010 |
| Domain families : Smart (EMBL) | HLH (SM00353) |
| Conserved Domain (NCBI) | PTF1A |
| DMDM Disease mutations | 256297 |
| Blocks (Seattle) | PTF1A |
| Superfamily | Q7RTS3 |
| Human Protein Atlas [tissue] | ENSG00000168267-PTF1A [tissue] |
| Peptide Atlas | Q7RTS3 |
| HPRD | 09526 |
| IPI | IPI00160766 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q7RTS3 |
| IntAct (EBI) | Q7RTS3 |
| FunCoup | ENSG00000168267 |
| BioGRID | PTF1A |
| STRING (EMBL) | PTF1A |
| ZODIAC | PTF1A |
| Ontologies - Pathways |
|---|
| QuickGO | Q7RTS3 |
| Ontology : AmiGO | RNA polymerase II distal enhancer sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding nucleus transcription factor complex cytoplasm regulation of transcription, DNA-templated tissue development retina layer formation cerebellum development pancreas development exocrine pancreas development amacrine cell differentiation positive regulation of transcription by RNA polymerase II protein dimerization activity retinoic acid receptor signaling pathway neuron fate commitment regulation of neural retina development E-box binding |
| Ontology : EGO-EBI | RNA polymerase II distal enhancer sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding nucleus transcription factor complex cytoplasm regulation of transcription, DNA-templated tissue development retina layer formation cerebellum development pancreas development exocrine pancreas development amacrine cell differentiation positive regulation of transcription by RNA polymerase II protein dimerization activity retinoic acid receptor signaling pathway neuron fate commitment regulation of neural retina development E-box binding |
| NDEx Network | PTF1A |
| Atlas of Cancer Signalling Network | PTF1A |
| Wikipedia pathways | PTF1A |
| Orthology - Evolution |
|---|
| OrthoDB | 256297 |
| GeneTree (enSembl) | ENSG00000168267 |
| Phylogenetic Trees/Animal Genes : TreeFam | PTF1A |
| HOGENOM | Q7RTS3 |
| Homologs : HomoloGene | PTF1A |
| Homology/Alignments : Family Browser (UCSC) | PTF1A |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | PTF1A |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | PTF1A [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | PTF1A |
| dbVar | PTF1A |
| ClinVar | PTF1A |
| 1000_Genomes | PTF1A |
| Exome Variant Server | PTF1A |
| ExAC (Exome Aggregation Consortium) | ENSG00000168267 |
| GNOMAD Browser | ENSG00000168267 |
| Varsome Browser | PTF1A |
| Genetic variants : HAPMAP | 256297 |
| Genomic Variants (DGV) | PTF1A [DGVbeta] |
| DECIPHER | PTF1A [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | PTF1A |
| Mutations |
|---|
| ICGC Data Portal | PTF1A |
| TCGA Data Portal | PTF1A |
| Broad Tumor Portal | PTF1A |
| OASIS Portal | PTF1A [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | PTF1A [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | PTF1A |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search PTF1A |
| DgiDB (Drug Gene Interaction Database) | PTF1A |
| DoCM (Curated mutations) | PTF1A (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | PTF1A (select a term) |
| intoGen | PTF1A |
| Cancer3D | PTF1A(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 607194 609069 615935 |
| Orphanet | 2548 10870 |
| DisGeNET | PTF1A |
| Medgen | PTF1A |
| Genetic Testing Registry | PTF1A
|
| NextProt | Q7RTS3 [Medical] |
| TSGene | 256297 |
| GENETests | PTF1A |
| Target Validation | PTF1A |
| Huge Navigator |
PTF1A [HugePedia] |
| snp3D : Map Gene to Disease | 256297 |
| BioCentury BCIQ | PTF1A |
| ClinGen | PTF1A |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 256297 |
| Chemical/Pharm GKB Gene | PA134864129 |
| Clinical trial | PTF1A |
| Miscellaneous |
|---|
| canSAR (ICR) | PTF1A (select the gene name) |
| DataMed Index | PTF1A |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 26 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | PTF1A |
| EVEX | PTF1A |
| GoPubMed | PTF1A |
| iHOP | PTF1A |
