Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PTGDR2 (prostaglandin D2 receptor 2)

Identity

Alias_namesGPR44
G protein-coupled receptor 44
Alias_symbol (synonym)CRTH2
CD294
DP2
Other aliasDL1R
HGNC (Hugo) PTGDR2
LocusID (NCBI) 11251
Atlas_Id 54870
Location 11q12.2  [Link to chromosome band 11q12]
Location_base_pair Starts at 60618398 and ends at 60623444 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTGDR2   4502
Cards
Entrez_Gene (NCBI)PTGDR2  11251  prostaglandin D2 receptor 2
AliasesCD294; CRTH2; DL1R; DP2; 
GPR44
GeneCards (Weizmann)PTGDR2
Ensembl hg19 (Hinxton)ENSG00000183134 [Gene_View]  chr11:60618398-60623444 [Contig_View]  PTGDR2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000183134 [Gene_View]  chr11:60618398-60623444 [Contig_View]  PTGDR2 [Vega]
ICGC DataPortalENSG00000183134
TCGA cBioPortalPTGDR2
AceView (NCBI)PTGDR2
Genatlas (Paris)PTGDR2
WikiGenes11251
SOURCE (Princeton)PTGDR2
Genetics Home Reference (NIH)PTGDR2
Genomic and cartography
GoldenPath hg19 (UCSC)PTGDR2  -     chr11:60618398-60623444 -  11q12.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PTGDR2  -     11q12.2   [Description]    (hg38-Dec_2013)
EnsemblPTGDR2 - 11q12.2 [CytoView hg19]  PTGDR2 - 11q12.2 [CytoView hg38]
Mapping of homologs : NCBIPTGDR2 [Mapview hg19]  PTGDR2 [Mapview hg38]
OMIM604837   
Gene and transcription
Genbank (Entrez)AB008535 AF144308 AK291371 AK313849 AY507142
RefSeq transcript (Entrez)NM_004778
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_016170 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)PTGDR2
Cluster EST : UnigeneHs.299567 [ NCBI ]
CGAP (NCI)Hs.299567
Alternative Splicing GalleryENSG00000183134
Gene ExpressionPTGDR2 [ NCBI-GEO ]   PTGDR2 [ EBI - ARRAY_EXPRESS ]   PTGDR2 [ SEEK ]   PTGDR2 [ MEM ]
Gene Expression Viewer (FireBrowse)PTGDR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11251
GTEX Portal (Tissue expression)PTGDR2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5Y4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5Y4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5Y4
Splice isoforms : SwissVarQ9Y5Y4
PhosPhoSitePlusQ9Y5Y4
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)PTGDR2
DMDM Disease mutations11251
Blocks (Seattle)PTGDR2
SuperfamilyQ9Y5Y4
Human Protein AtlasENSG00000183134
Peptide AtlasQ9Y5Y4
HPRD16075
IPIIPI00001921   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5Y4
IntAct (EBI)Q9Y5Y4
FunCoupENSG00000183134
BioGRIDPTGDR2
STRING (EMBL)PTGDR2
ZODIACPTGDR2
Ontologies - Pathways
QuickGOQ9Y5Y4
Ontology : AmiGOprostaglandin J receptor activity  G-protein coupled receptor activity  prostaglandin D receptor activity  prostaglandin F receptor activity  intracellular  intracellular  plasma membrane  integral component of plasma membrane  chemotaxis  immune response  G-protein coupled receptor signaling pathway  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  synaptic transmission  calcium-mediated signaling  neuropeptide binding  neuron projection  positive regulation of G-protein coupled receptor protein signaling pathway  negative regulation of male germ cell proliferation  
Ontology : EGO-EBIprostaglandin J receptor activity  G-protein coupled receptor activity  prostaglandin D receptor activity  prostaglandin F receptor activity  intracellular  intracellular  plasma membrane  integral component of plasma membrane  chemotaxis  immune response  G-protein coupled receptor signaling pathway  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  neuropeptide signaling pathway  synaptic transmission  calcium-mediated signaling  neuropeptide binding  neuron projection  positive regulation of G-protein coupled receptor protein signaling pathway  negative regulation of male germ cell proliferation  
NDEx NetworkPTGDR2
Atlas of Cancer Signalling NetworkPTGDR2
Wikipedia pathwaysPTGDR2
Orthology - Evolution
OrthoDB11251
GeneTree (enSembl)ENSG00000183134
Phylogenetic Trees/Animal Genes : TreeFamPTGDR2
HOVERGENQ9Y5Y4
HOGENOMQ9Y5Y4
Homologs : HomoloGenePTGDR2
Homology/Alignments : Family Browser (UCSC)PTGDR2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTGDR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTGDR2
dbVarPTGDR2
ClinVarPTGDR2
1000_GenomesPTGDR2 
Exome Variant ServerPTGDR2
ExAC (Exome Aggregation Consortium)PTGDR2 (select the gene name)
Genetic variants : HAPMAP11251
Genomic Variants (DGV)PTGDR2 [DGVbeta]
DECIPHER (Syndromes)11:60618398-60623444  ENSG00000183134
CONAN: Copy Number AnalysisPTGDR2 
Mutations
ICGC Data PortalPTGDR2 
TCGA Data PortalPTGDR2 
Broad Tumor PortalPTGDR2
OASIS PortalPTGDR2 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPTGDR2
BioMutasearch PTGDR2
DgiDB (Drug Gene Interaction Database)PTGDR2
DoCM (Curated mutations)PTGDR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTGDR2 (select a term)
intoGenPTGDR2
Cancer3DPTGDR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604837   
Orphanet
MedgenPTGDR2
Genetic Testing Registry PTGDR2
NextProtQ9Y5Y4 [Medical]
TSGene11251
GENETestsPTGDR2
Huge Navigator PTGDR2 [HugePedia]
snp3D : Map Gene to Disease11251
BioCentury BCIQPTGDR2
ClinGenPTGDR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11251
Chemical/Pharm GKB GenePA28891
Clinical trialPTGDR2
Miscellaneous
canSAR (ICR)PTGDR2 (select the gene name)
Probes
Litterature
PubMed58 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTGDR2
EVEXPTGDR2
GoPubMedPTGDR2
iHOPPTGDR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:16:08 CEST 2017

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