Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PTGER2 (prostaglandin E receptor 2)

Identity

Alias (NCBI)EP2
HGNC (Hugo) PTGER2
HGNC Alias symbEP2
HGNC Previous nameprostaglandin E receptor 2 (subtype EP2), 53kD
 prostaglandin E receptor 2 (subtype EP2), 53kDa
LocusID (NCBI) 5732
Atlas_Id 46566
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 52314312 and ends at 52328595 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PTGER2   9594
Cards
Entrez_Gene (NCBI)PTGER2    prostaglandin E receptor 2
AliasesEP2
GeneCards (Weizmann)PTGER2
Ensembl hg19 (Hinxton)ENSG00000125384 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125384 [Gene_View]  ENSG00000125384 [Sequence]  chr14:52314312-52328595 [Contig_View]  PTGER2 [Vega]
ICGC DataPortalENSG00000125384
TCGA cBioPortalPTGER2
AceView (NCBI)PTGER2
Genatlas (Paris)PTGER2
SOURCE (Princeton)PTGER2
Genetics Home Reference (NIH)PTGER2
Genomic and cartography
GoldenPath hg38 (UCSC)PTGER2  -     chr14:52314312-52328595 +  14q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PTGER2  -     14q22.1   [Description]    (hg19-Feb_2009)
GoldenPathPTGER2 - 14q22.1 [CytoView hg19]  PTGER2 - 14q22.1 [CytoView hg38]
ImmunoBaseENSG00000125384
Genome Data Viewer NCBIPTGER2 [Mapview hg19]  
OMIM176804   208550   
Gene and transcription
Genbank (Entrez)AY275471 BC093927 BC093929 BE739744 BF029797
RefSeq transcript (Entrez)NM_000956
Consensus coding sequences : CCDS (NCBI)PTGER2
Gene ExpressionPTGER2 [ NCBI-GEO ]   PTGER2 [ EBI - ARRAY_EXPRESS ]   PTGER2 [ SEEK ]   PTGER2 [ MEM ]
Gene Expression Viewer (FireBrowse)PTGER2 [ Firebrowse - Broad ]
GenevisibleExpression of PTGER2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5732
GTEX Portal (Tissue expression)PTGER2
Human Protein AtlasENSG00000125384-PTGER2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43116   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43116  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43116
PhosPhoSitePlusP43116
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Prostanoid_rcpt    Prostglndn_EP2_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)PTGER2
SuperfamilyP43116
AlphaFold pdb e-kbP43116   
Human Protein Atlas [tissue]ENSG00000125384-PTGER2 [tissue]
HPRD08905
Protein Interaction databases
DIP (DOE-UCLA)P43116
IntAct (EBI)P43116
BioGRIDPTGER2
STRING (EMBL)PTGER2
ZODIACPTGER2
Ontologies - Pathways
QuickGOP43116
Ontology : AmiGOprostaglandin E receptor activity  plasma membrane  plasma membrane  integral component of plasma membrane  inflammatory response  G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  response to lipopolysaccharide  response to progesterone  regulation of cell population proliferation  cellular response to prostaglandin E stimulus  cellular response to prostaglandin E stimulus  
Ontology : EGO-EBIprostaglandin E receptor activity  plasma membrane  plasma membrane  integral component of plasma membrane  inflammatory response  G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  adenylate cyclase-activating G protein-coupled receptor signaling pathway  positive regulation of cytosolic calcium ion concentration  response to lipopolysaccharide  response to progesterone  regulation of cell population proliferation  cellular response to prostaglandin E stimulus  cellular response to prostaglandin E stimulus  
Pathways : BIOCARTABIOCARTA_EICOSANOIDPATHWAY   
Pathways : KEGGKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION   
NDEx NetworkPTGER2
Atlas of Cancer Signalling NetworkPTGER2
Wikipedia pathwaysPTGER2
Orthology - Evolution
OrthoDB5732
GeneTree (enSembl)ENSG00000125384
Phylogenetic Trees/Animal Genes : TreeFamPTGER2
Homologs : HomoloGenePTGER2
Homology/Alignments : Family Browser (UCSC)PTGER2
Gene fusions - Rearrangements
Fusion : QuiverPTGER2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTGER2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTGER2
dbVarPTGER2
ClinVarPTGER2
MonarchPTGER2
1000_GenomesPTGER2 
Exome Variant ServerPTGER2
GNOMAD BrowserENSG00000125384
Varsome BrowserPTGER2
ACMGPTGER2 variants
VarityP43116
Genomic Variants (DGV)PTGER2 [DGVbeta]
DECIPHERPTGER2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPTGER2 
Mutations
ICGC Data PortalPTGER2 
TCGA Data PortalPTGER2 
Broad Tumor PortalPTGER2
OASIS PortalPTGER2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTGER2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPTGER2
Mutations and Diseases : HGMDPTGER2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPTGER2
DgiDB (Drug Gene Interaction Database)PTGER2
DoCM (Curated mutations)PTGER2
CIViC (Clinical Interpretations of Variants in Cancer)PTGER2
Cancer3DPTGER2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176804    208550   
Orphanet
DisGeNETPTGER2
MedgenPTGER2
Genetic Testing Registry PTGER2
NextProtP43116 [Medical]
GENETestsPTGER2
Target ValidationPTGER2
Huge Navigator PTGER2 [HugePedia]
ClinGenPTGER2
Clinical trials, drugs, therapy
MyCancerGenomePTGER2
Protein Interactions : CTDPTGER2
Pharm GKB GenePA287
Pharm GKB PathwaysPA152241951   PA154444041   PA166121942   
PharosP43116
Clinical trialPTGER2
Miscellaneous
canSAR (ICR)PTGER2
HarmonizomePTGER2
ARCHS4PTGER2
DataMed IndexPTGER2
Probes
Litterature
PubMed152 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPTGER2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Jan 20 12:54:29 CET 2022

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