Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PTGER2 (prostaglandin E receptor 2)

Identity

Alias_namesprostaglandin E receptor 2 (subtype EP2), 53kD
prostaglandin E receptor 2 (subtype EP2), 53kDa
Alias_symbol (synonym)EP2
Other alias
HGNC (Hugo) PTGER2
LocusID (NCBI) 5732
Atlas_Id 46566
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 52781016 and ends at 52795322 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTGER2   9594
Cards
Entrez_Gene (NCBI)PTGER2  5732  prostaglandin E receptor 2
AliasesEP2
GeneCards (Weizmann)PTGER2
Ensembl hg19 (Hinxton)ENSG00000125384 [Gene_View]  chr14:52781016-52795322 [Contig_View]  PTGER2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000125384 [Gene_View]  chr14:52781016-52795322 [Contig_View]  PTGER2 [Vega]
ICGC DataPortalENSG00000125384
TCGA cBioPortalPTGER2
AceView (NCBI)PTGER2
Genatlas (Paris)PTGER2
WikiGenes5732
SOURCE (Princeton)PTGER2
Genetics Home Reference (NIH)PTGER2
Genomic and cartography
GoldenPath hg19 (UCSC)PTGER2  -     chr14:52781016-52795322 +  14q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PTGER2  -     14q22.1   [Description]    (hg38-Dec_2013)
EnsemblPTGER2 - 14q22.1 [CytoView hg19]  PTGER2 - 14q22.1 [CytoView hg38]
Mapping of homologs : NCBIPTGER2 [Mapview hg19]  PTGER2 [Mapview hg38]
OMIM176804   208550   
Gene and transcription
Genbank (Entrez)AY275471 BC093927 BC093929 BE739744 BF029797
RefSeq transcript (Entrez)NM_000956
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_013082 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)PTGER2
Cluster EST : UnigeneHs.2090 [ NCBI ]
CGAP (NCI)Hs.2090
Alternative Splicing GalleryENSG00000125384
Gene ExpressionPTGER2 [ NCBI-GEO ]   PTGER2 [ EBI - ARRAY_EXPRESS ]   PTGER2 [ SEEK ]   PTGER2 [ MEM ]
Gene Expression Viewer (FireBrowse)PTGER2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5732
GTEX Portal (Tissue expression)PTGER2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43116   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43116  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43116
Splice isoforms : SwissVarP43116
PhosPhoSitePlusP43116
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Prostanoid_rcpt    Prostglndn_EP2_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)PTGER2
DMDM Disease mutations5732
Blocks (Seattle)PTGER2
SuperfamilyP43116
Human Protein AtlasENSG00000125384
Peptide AtlasP43116
HPRD08905
IPIIPI00016314   IPI01026228   
Protein Interaction databases
DIP (DOE-UCLA)P43116
IntAct (EBI)P43116
FunCoupENSG00000125384
BioGRIDPTGER2
STRING (EMBL)PTGER2
ZODIACPTGER2
Ontologies - Pathways
QuickGOP43116
Ontology : AmiGOprostaglandin E receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  response to lipopolysaccharide  response to progesterone  regulation of cell proliferation  cellular response to prostaglandin E stimulus  
Ontology : EGO-EBIprostaglandin E receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  adenylate cyclase-activating G-protein coupled receptor signaling pathway  response to lipopolysaccharide  response to progesterone  regulation of cell proliferation  cellular response to prostaglandin E stimulus  
Pathways : BIOCARTAEicosanoid Metabolism [Genes]   
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkPTGER2
Atlas of Cancer Signalling NetworkPTGER2
Wikipedia pathwaysPTGER2
Orthology - Evolution
OrthoDB5732
GeneTree (enSembl)ENSG00000125384
Phylogenetic Trees/Animal Genes : TreeFamPTGER2
HOVERGENP43116
HOGENOMP43116
Homologs : HomoloGenePTGER2
Homology/Alignments : Family Browser (UCSC)PTGER2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTGER2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTGER2
dbVarPTGER2
ClinVarPTGER2
1000_GenomesPTGER2 
Exome Variant ServerPTGER2
ExAC (Exome Aggregation Consortium)PTGER2 (select the gene name)
Genetic variants : HAPMAP5732
Genomic Variants (DGV)PTGER2 [DGVbeta]
DECIPHER (Syndromes)14:52781016-52795322  ENSG00000125384
CONAN: Copy Number AnalysisPTGER2 
Mutations
ICGC Data PortalPTGER2 
TCGA Data PortalPTGER2 
Broad Tumor PortalPTGER2
OASIS PortalPTGER2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTGER2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPTGER2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PTGER2
DgiDB (Drug Gene Interaction Database)PTGER2
DoCM (Curated mutations)PTGER2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTGER2 (select a term)
intoGenPTGER2
Cancer3DPTGER2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM176804    208550   
Orphanet
MedgenPTGER2
Genetic Testing Registry PTGER2
NextProtP43116 [Medical]
TSGene5732
GENETestsPTGER2
Huge Navigator PTGER2 [HugePedia]
snp3D : Map Gene to Disease5732
BioCentury BCIQPTGER2
ClinGenPTGER2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5732
Chemical/Pharm GKB GenePA287
Clinical trialPTGER2
Miscellaneous
canSAR (ICR)PTGER2 (select the gene name)
Probes
Litterature
PubMed121 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTGER2
EVEXPTGER2
GoPubMedPTGER2
iHOPPTGER2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:16:09 CEST 2017

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