Identity
HGNC
LOCATION
1p31.1
LOCUSID
ALIAS
EP3,EP3-I,EP3-II,EP3-III,EP3-IV,EP3-VI,EP3e,PGE2-R,lnc003875
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5733
MIM: 176806
HGNC: 9595
Ensembl: ENSG00000050628
Variants:
dbSNP: 5733
ClinVar: 5733
TCGA: ENSG00000050628
COSMIC: PTGER3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164712308 | Ace Inhibitors, Plain | Chemical | ClinicalAnnotation | associated | PD | 21052031 | |
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 17496729 | |
| PA443803 | Cough | Disease | ClinicalAnnotation | associated | PD | 21052031 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 21052031 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 17496729 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38566528 | 2024 | PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis. | 1 |
| 38566528 | 2024 | PTGER3 knockdown inhibits the vulnerability of triple-negative breast cancer to ferroptosis. | 1 |
| 35113749 | 2023 | Altered Prostaglandin E Receptor Subtype 3 Expression in Lacrimal Glands of Patients with Chronic Stevens-Johnson Syndrome. | 0 |
| 36578105 | 2023 | E prostanoid receptor-3 promotes oxidized low-density lipoprotein-induced human aortic smooth muscle cells inflammation. | 1 |
| 35113749 | 2023 | Altered Prostaglandin E Receptor Subtype 3 Expression in Lacrimal Glands of Patients with Chronic Stevens-Johnson Syndrome. | 0 |
| 36578105 | 2023 | E prostanoid receptor-3 promotes oxidized low-density lipoprotein-induced human aortic smooth muscle cells inflammation. | 1 |
| 34822808 | 2022 | Prostaglandin E2 EP receptors in cardiovascular disease: An update. | 13 |
| 35134851 | 2022 | Prostaglandin E2 receptor 3 promotes M1 macrophages polarization in unexplained recurrent pregnancy loss. | 6 |
| 35781818 | 2022 | PGE(2) -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase. | 2 |
| 34822808 | 2022 | Prostaglandin E2 EP receptors in cardiovascular disease: An update. | 13 |
| 35134851 | 2022 | Prostaglandin E2 receptor 3 promotes M1 macrophages polarization in unexplained recurrent pregnancy loss. | 6 |
| 35781818 | 2022 | PGE(2) -EP3 axis promotes brown adipose tissue formation through stabilization of WTAP RNA methyltransferase. | 2 |
| 32488496 | 2020 | Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR). | 9 |
| 32580276 | 2020 | EP3 Is an Independent Prognostic Marker Only for Unifocal Breast Cancer Cases. | 2 |
| 32488496 | 2020 | Prostaglandin E2 receptor 3 (EP3) signaling promotes migration of cervical cancer via urokinase-type plasminogen activator receptor (uPAR). | 9 |
Citation
Dessen P
PTGER3 (prostaglandin E receptor 3)
Atlas Genet Cytogenet Oncol Haematol. 2010-04-01
Online version: http://atlasgeneticsoncology.org/gene/51416/ptger3
