Atlas of Genetics and Cytogenetics in Oncology and Haematology


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PTGFRN (prostaglandin F2 receptor inhibitor)

Identity

Alias_namesprostaglandin F2 receptor negative regulator
Alias_symbol (synonym)FPRP
EWI-F
CD9P-1
FLJ11001
KIAA1436
SMAP-6
CD315
Other alias
HGNC (Hugo) PTGFRN
LocusID (NCBI) 5738
Atlas_Id 52161
Location 1p13.1  [Link to chromosome band 1p13]
Location_base_pair Starts at 116909923 and ends at 116990358 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PTGFRN (1p13.1) / AGBL4 (1p33)PTGFRN (1p13.1) / NOTCH2 (1p12)PTGFRN (1p13.1) / PTGFRN (1p13.1)
VTCN1 (1p13.1) / PTGFRN (1p13.1)PTGFRN 1p13.1 / AGBL4 1p33PTGFRN 1p13.1 / NOTCH2 1p12
VTCN1 1p13.1 / PTGFRN 1p13.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTGFRN   9601
Cards
Entrez_Gene (NCBI)PTGFRN  5738  prostaglandin F2 receptor inhibitor
AliasesCD315; CD9P-1; EWI-F; FPRP; 
SMAP-6
GeneCards (Weizmann)PTGFRN
Ensembl hg19 (Hinxton)ENSG00000134247 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134247 [Gene_View]  chr1:116909923-116990358 [Contig_View]  PTGFRN [Vega]
ICGC DataPortalENSG00000134247
TCGA cBioPortalPTGFRN
AceView (NCBI)PTGFRN
Genatlas (Paris)PTGFRN
WikiGenes5738
SOURCE (Princeton)PTGFRN
Genetics Home Reference (NIH)PTGFRN
Genomic and cartography
GoldenPath hg38 (UCSC)PTGFRN  -     chr1:116909923-116990358 +  1p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PTGFRN  -     1p13.1   [Description]    (hg19-Feb_2009)
EnsemblPTGFRN - 1p13.1 [CytoView hg19]  PTGFRN - 1p13.1 [CytoView hg38]
Mapping of homologs : NCBIPTGFRN [Mapview hg19]  PTGFRN [Mapview hg38]
OMIM601204   
Gene and transcription
Genbank (Entrez)AA045111 AB014734 AB037857 AK001863 AK024785
RefSeq transcript (Entrez)NM_020440
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PTGFRN
Cluster EST : UnigeneHs.418093 [ NCBI ]
CGAP (NCI)Hs.418093
Alternative Splicing GalleryENSG00000134247
Gene ExpressionPTGFRN [ NCBI-GEO ]   PTGFRN [ EBI - ARRAY_EXPRESS ]   PTGFRN [ SEEK ]   PTGFRN [ MEM ]
Gene Expression Viewer (FireBrowse)PTGFRN [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5738
GTEX Portal (Tissue expression)PTGFRN
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2B2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2B2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2B2
Splice isoforms : SwissVarQ9P2B2
PhosPhoSitePlusQ9P2B2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGv (SM00406)  
Conserved Domain (NCBI)PTGFRN
DMDM Disease mutations5738
Blocks (Seattle)PTGFRN
SuperfamilyQ9P2B2
Human Protein AtlasENSG00000134247
Peptide AtlasQ9P2B2
HPRD03124
IPIIPI00022048   IPI01012315   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2B2
IntAct (EBI)Q9P2B2
FunCoupENSG00000134247
BioGRIDPTGFRN
STRING (EMBL)PTGFRN
ZODIACPTGFRN
Ontologies - Pathways
QuickGOQ9P2B2
Ontology : AmiGOprotein binding  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  cell surface  integral component of membrane  lipid particle organization  
Ontology : EGO-EBIprotein binding  endoplasmic reticulum membrane  Golgi apparatus  plasma membrane  cell surface  integral component of membrane  lipid particle organization  
NDEx NetworkPTGFRN
Atlas of Cancer Signalling NetworkPTGFRN
Wikipedia pathwaysPTGFRN
Orthology - Evolution
OrthoDB5738
GeneTree (enSembl)ENSG00000134247
Phylogenetic Trees/Animal Genes : TreeFamPTGFRN
HOVERGENQ9P2B2
HOGENOMQ9P2B2
Homologs : HomoloGenePTGFRN
Homology/Alignments : Family Browser (UCSC)PTGFRN
Gene fusions - Rearrangements
Fusion : MitelmanPTGFRN/AGBL4 [1p13.1/1p33]  
Fusion : MitelmanPTGFRN/NOTCH2 [1p13.1/1p12]  [t(1;1)(p12;p13)]  
Fusion : MitelmanVTCN1/PTGFRN [1p13.1/1p13.1]  [t(1;1)(p13;p13)]  
Fusion: TCGAPTGFRN 1p13.1 AGBL4 1p33 BRCA
Fusion: TCGAPTGFRN 1p13.1 NOTCH2 1p12 BRCA
Fusion: TCGAVTCN1 1p13.1 PTGFRN 1p13.1 OV
Fusion Cancer (Beijing)PTGFRN [1p13.1]  -  NOTCH2 [1p12]  [FUSC001899]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTGFRN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTGFRN
dbVarPTGFRN
ClinVarPTGFRN
1000_GenomesPTGFRN 
Exome Variant ServerPTGFRN
ExAC (Exome Aggregation Consortium)PTGFRN (select the gene name)
Genetic variants : HAPMAP5738
Genomic Variants (DGV)PTGFRN [DGVbeta]
DECIPHERPTGFRN [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPTGFRN 
Mutations
ICGC Data PortalPTGFRN 
TCGA Data PortalPTGFRN 
Broad Tumor PortalPTGFRN
OASIS PortalPTGFRN [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTGFRN  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPTGFRN
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PTGFRN
DgiDB (Drug Gene Interaction Database)PTGFRN
DoCM (Curated mutations)PTGFRN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTGFRN (select a term)
intoGenPTGFRN
Cancer3DPTGFRN(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601204   
Orphanet
MedgenPTGFRN
Genetic Testing Registry PTGFRN
NextProtQ9P2B2 [Medical]
TSGene5738
GENETestsPTGFRN
Target ValidationPTGFRN
Huge Navigator PTGFRN [HugePedia]
snp3D : Map Gene to Disease5738
BioCentury BCIQPTGFRN
ClinGenPTGFRN
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5738
Chemical/Pharm GKB GenePA33950
Clinical trialPTGFRN
Miscellaneous
canSAR (ICR)PTGFRN (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTGFRN
EVEXPTGFRN
GoPubMedPTGFRN
iHOPPTGFRN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:12:03 CEST 2017

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