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PTH2R (parathyroid hormone 2 receptor)

Identity

Alias_namesPTHR2
parathyroid hormone receptor 2
Other alias
HGNC (Hugo) PTH2R
LocusID (NCBI) 5746
Atlas_Id 72382
Location 2q34  [Link to chromosome band 2q34]
Location_base_pair Starts at 209271555 and ends at 209359231 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MOCS2 (5q11.2) / PTH2R (2q34)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTH2R   9609
Cards
Entrez_Gene (NCBI)PTH2R  5746  parathyroid hormone 2 receptor
AliasesPTHR2
GeneCards (Weizmann)PTH2R
Ensembl hg19 (Hinxton)ENSG00000144407 [Gene_View]  chr2:209271555-209359231 [Contig_View]  PTH2R [Vega]
Ensembl hg38 (Hinxton)ENSG00000144407 [Gene_View]  chr2:209271555-209359231 [Contig_View]  PTH2R [Vega]
ICGC DataPortalENSG00000144407
TCGA cBioPortalPTH2R
AceView (NCBI)PTH2R
Genatlas (Paris)PTH2R
WikiGenes5746
SOURCE (Princeton)PTH2R
Genetics Home Reference (NIH)PTH2R
Genomic and cartography
GoldenPath hg19 (UCSC)PTH2R  -     chr2:209271555-209359231 +  2q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PTH2R  -     2q34   [Description]    (hg38-Dec_2013)
EnsemblPTH2R - 2q34 [CytoView hg19]  PTH2R - 2q34 [CytoView hg38]
Mapping of homologs : NCBIPTH2R [Mapview hg19]  PTH2R [Mapview hg38]
OMIM601469   
Gene and transcription
Genbank (Entrez)AK294181 AK309827 AY497546 BC036811 BM808818
RefSeq transcript (Entrez)NM_005048
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)PTH2R
Cluster EST : UnigeneHs.570296 [ NCBI ]
CGAP (NCI)Hs.570296
Alternative Splicing GalleryENSG00000144407
Gene ExpressionPTH2R [ NCBI-GEO ]   PTH2R [ EBI - ARRAY_EXPRESS ]   PTH2R [ SEEK ]   PTH2R [ MEM ]
Gene Expression Viewer (FireBrowse)PTH2R [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5746
GTEX Portal (Tissue expression)PTH2R
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49190   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49190  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49190
Splice isoforms : SwissVarP49190
PhosPhoSitePlusP49190
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F2_1 (PS00649)    G_PROTEIN_RECEP_F2_2 (PS00650)    G_PROTEIN_RECEP_F2_3 (PS50227)    G_PROTEIN_RECEP_F2_4 (PS50261)   
Domains : Interpro (EBI)GPCR_2-like    GPCR_2_extracellular_dom    GPCR_2_secretin-like    GPCR_2_secretin-like_CS   
Domain families : Pfam (Sanger)7tm_2 (PF00002)    HRM (PF02793)   
Domain families : Pfam (NCBI)pfam00002    pfam02793   
Domain families : Smart (EMBL)HormR (SM00008)  
Conserved Domain (NCBI)PTH2R
DMDM Disease mutations5746
Blocks (Seattle)PTH2R
SuperfamilyP49190
Human Protein AtlasENSG00000144407
Peptide AtlasP49190
HPRD03276
IPIIPI00927172   IPI00927401   
Protein Interaction databases
DIP (DOE-UCLA)P49190
IntAct (EBI)P49190
FunCoupENSG00000144407
BioGRIDPTH2R
STRING (EMBL)PTH2R
ZODIACPTH2R
Ontologies - Pathways
QuickGOP49190
Ontology : AmiGOparathyroid hormone receptor activity  protein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  
Ontology : EGO-EBIparathyroid hormone receptor activity  protein binding  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway  
Pathways : KEGGNeuroactive ligand-receptor interaction   
NDEx NetworkPTH2R
Atlas of Cancer Signalling NetworkPTH2R
Wikipedia pathwaysPTH2R
Orthology - Evolution
OrthoDB5746
GeneTree (enSembl)ENSG00000144407
Phylogenetic Trees/Animal Genes : TreeFamPTH2R
HOVERGENP49190
HOGENOMP49190
Homologs : HomoloGenePTH2R
Homology/Alignments : Family Browser (UCSC)PTH2R
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTH2R [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTH2R
dbVarPTH2R
ClinVarPTH2R
1000_GenomesPTH2R 
Exome Variant ServerPTH2R
ExAC (Exome Aggregation Consortium)PTH2R (select the gene name)
Genetic variants : HAPMAP5746
Genomic Variants (DGV)PTH2R [DGVbeta]
DECIPHER (Syndromes)2:209271555-209359231  ENSG00000144407
CONAN: Copy Number AnalysisPTH2R 
Mutations
ICGC Data PortalPTH2R 
TCGA Data PortalPTH2R 
Broad Tumor PortalPTH2R
OASIS PortalPTH2R [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTH2R  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDPTH2R
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch PTH2R
DgiDB (Drug Gene Interaction Database)PTH2R
DoCM (Curated mutations)PTH2R (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTH2R (select a term)
intoGenPTH2R
Cancer3DPTH2R(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601469   
Orphanet
MedgenPTH2R
Genetic Testing Registry PTH2R
NextProtP49190 [Medical]
TSGene5746
GENETestsPTH2R
Huge Navigator PTH2R [HugePedia]
snp3D : Map Gene to Disease5746
BioCentury BCIQPTH2R
ClinGenPTH2R
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5746
Chemical/Pharm GKB GenePA162400333
Clinical trialPTH2R
Miscellaneous
canSAR (ICR)PTH2R (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTH2R
EVEXPTH2R
GoPubMedPTH2R
iHOPPTH2R
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:40:11 CET 2017

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