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PTPN14 (protein tyrosine phosphatase, non-receptor type 14)

Identity

Other namesMGC126803
PEZ
PTP36
HGNC (Hugo) PTPN14
Location 1q41
Location_base_pair Starts at 214531011 and ends at 214724642 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PTPN14   9647
Entrez_Gene (NCBI)PTPN14  5784  protein tyrosine phosphatase, non-receptor type 14
Cards
GeneCards (Weizmann)PTPN14
Ensembl (Hinxton)ENSG00000152104 [Gene_View]  PTPN14 [Vega]
AceView (NCBI)PTPN14
Genatlas (Paris)PTPN14
euGene (Indiana)5784
SOURCE (Stanford)NM_005401
Gene Expression (Array Express) ENSG00000152104
Genomic and cartography
GoldenPath (UCSC)PTPN14  -  1q41   chr1:214531011-214724642 -  1q41   [Description]    (hg19-Feb_2009)
EnsemblPTPN14 - 1q41 [CytoView]
Mapping of homologs : NCBIPTPN14 [Mapview]
OMIM603155   
Gene and transcription
Gene : Genbank (Entrez)AK090596 AK291641 AK298120 AW192897 BC017300
Reference sequence (RefSeq transcript) :SRSNM_005401
Reference transcript : EntrezNM_005401
RefSeq genomic : SRSAC_000044 AC_000133 NC_000001 NT_167186 NW_001838537 NW_926794
RefSeq genomic : EntrezAC_000044 AC_000133 NC_000001 NT_167186 NW_001838537 NW_926794
Consensus coding sequences : CCDS NCBIPTPN14
Cluster EST : UnigeneHs.696573 [ SRS ] Hs.696573 [ NCBI ]
Alternative Splicing : Fast-db (Paris)17829
Protein : pattern, domain, 3D structure
Protein : UniProt/SwissProtQ15678 (SRS) Q15678 (Expasy) Q15678 (Uniprot)
With graphics : InterProQ15678
Splice isoforms : VarSplice FASTAQ15678(VarSplice FASTA)
Domaine pattern : Prosite (SRS)FERM_1 (PS00660)    FERM_2 (PS00661)    FERM_3 (PS50057)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domain pattern : Prosite (Expaxy)FERM_1 (PS00660)    FERM_2 (PS00661)    FERM_3 (PS50057)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (SRS)Band_41_domain    Band_41_sg    Dual-sp/Tyr_phosphatase    FERM/acyl-CoA_bd_prot_3-hlx    FERM_central    FERM_CS    FERM_domain    FERM_N    FERM_PH-like_C    PH_type    Tyr_Pase_AS    Tyr_Pase_non-rcpt_typ-14/21    Tyr_Pase_rcpt/non-rcpt   
Domains : Interpro (EBI)Band_41_domain    Band_41_sg    Dual-sp/Tyr_phosphatase    FERM/acyl-CoA_bd_prot_3-hlx    FERM_central    FERM_CS    FERM_domain    FERM_N    FERM_PH-like_C    PH_type    Tyr_Pase_AS    Tyr_Pase_non-rcpt_typ-14/21    Tyr_Pase_rcpt/non-rcpt   
Related proteins : CluSTrQ15678
Domain families : Pfam SRSFERM_C (PF09380)    FERM_M (PF00373)    FERM_N (PF09379)    Y_phosphatase (PF00102)   
Domain families : Pfam SangerFERM_C (PF09380)    FERM_M (PF00373)    FERM_N (PF09379)    Y_phosphatase (PF00102)   
Domain families : Pfam NCBIpfam09380    pfam00373    pfam09379    pfam00102   
Domain families : Smart EMBLB41 (SM00295)  PTPc (SM00194)  
Blocks (Seattle)Q15678
Crystal structure of protein : PDB SRS2BZL   
Crystal structure of protein : PDBSum2BZL   
Crystal structure of protein : IMB2BZL   
Crystal structure of protein : PDB RSDB2BZL   
Human Protein AtlasENSG00000152104
HPRD04402
Protein Interaction databases
DIP (DOE-UCLA)Q15678
IntAct (EBI)Q15678
FunCoupENSG00000152104
Polymorphism : SNP, mutations, diseases
Single Nucleotide Polymorphism (SNP) : dbSNP NCBIPTPN14
SNP : GeneSNP UtahPTPN14
SNP : HGBasePTPN14
Genetic variants : HAPMAPPTPN14
Somatic Mutations in Cancer : COSMICPTPN14 
Mutations and Diseases : HGMDPTPN14
Hereditary diseases : OMIM603155   
Hereditary diseases : GENETests603155   
Diseases : Genetic AssociationPTPN14
General knowledge
Homologs : HomoloGenePTPN14
Homology/Alignments : Family Browser UCSCPTPN14
Phylogenetic Trees/Animal Genes : TreeFamPTPN14
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.48 [ Enzyme-SRS ]   3.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
Chemical/Protein Interactions : CTD5784
Keywords Ontology : AmiGOprotein tyrosine phosphatase activity  binding  cytoplasm  cytoskeleton  protein amino acid dephosphorylation  hydrolase activity  
Keywords Ontology : EGO-EBIprotein tyrosine phosphatase activity  binding  cytoplasm  cytoskeleton  protein amino acid dephosphorylation  hydrolase activity  
Pathways : BIOCARTA
Pathways : KEGG
Other databases
Probes
Probes : ImagenesPTPN14 Related clones (RZPD - Berlin)
Literature
PubMed14 Pubmed reference(s) in Entrez
PubGenePTPN14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated05-2010Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 9 11:29:28 CEST 2010
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