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PTPN20 (protein tyrosine phosphatase, non-receptor type 20)

Identity

Alias_namesPTPN20A
PTPN20B
protein tyrosine phosphatase, non-receptor type 20A
protein tyrosine phosphatase, non-receptor type 20B
Alias_symbol (synonym)bA42B19.1
DKFZP566K0524
bA142I17.1
CT126
Other aliashPTPN20
HGNC (Hugo) PTPN20
LocusID (NCBI) 26095
Atlas_Id 77515
Location 10q11.22  [Link to chromosome band 10q11]
Location_base_pair Starts at 46550123 and ends at 46620058 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)PTPN20   23423
Cards
Entrez_Gene (NCBI)PTPN20  26095  protein tyrosine phosphatase, non-receptor type 20
AliasesCT126; PTPN20A; PTPN20B; bA142I17.1; 
bA42B19.1; hPTPN20
GeneCards (Weizmann)PTPN20
Ensembl hg19 (Hinxton)ENSG00000204179 [Gene_View]  chr10:46550123-46620058 [Contig_View]  PTPN20 [Vega]
Ensembl hg38 (Hinxton)ENSG00000204179 [Gene_View]  chr10:46550123-46620058 [Contig_View]  PTPN20 [Vega]
ICGC DataPortalENSG00000204179
TCGA cBioPortalPTPN20
AceView (NCBI)PTPN20
Genatlas (Paris)PTPN20
WikiGenes26095
SOURCE (Princeton)PTPN20
Genetics Home Reference (NIH)PTPN20
Genomic and cartography
GoldenPath hg19 (UCSC)PTPN20  -     chr10:46550123-46620058 -  10q11.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)PTPN20  -     10q11.22   [Description]    (hg38-Dec_2013)
EnsemblPTPN20 - 10q11.22 [CytoView hg19]  PTPN20 - 10q11.22 [CytoView hg38]
Mapping of homologs : NCBIPTPN20 [Mapview hg19]  PTPN20 [Mapview hg38]
OMIM610630   610631   
Gene and transcription
Genbank (Entrez)AK309922 AL050040 AY704141 AY704142 AY704143
RefSeq transcript (Entrez)NM_001042357 NM_001042358 NM_001042359 NM_001042360 NM_001042361 NM_001042362 NM_001042363 NM_001042364 NM_001042365 NM_001042387 NM_001042389 NM_001042390 NM_001042391 NM_001042392 NM_001042393 NM_001042394 NM_001042395 NM_001042396 NM_001042397 NM_015605
RefSeq genomic (Entrez)NC_000010 NC_018921 NT_030059 NW_004929376
Consensus coding sequences : CCDS (NCBI)PTPN20
Cluster EST : UnigeneHs.650752 [ NCBI ]
CGAP (NCI)Hs.650752
Alternative Splicing GalleryENSG00000204179
Gene ExpressionPTPN20 [ NCBI-GEO ]   PTPN20 [ EBI - ARRAY_EXPRESS ]   PTPN20 [ SEEK ]   PTPN20 [ MEM ]
Gene Expression Viewer (FireBrowse)PTPN20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26095
GTEX Portal (Tissue expression)PTPN20
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ4JDL3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ4JDL3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ4JDL3
Splice isoforms : SwissVarQ4JDL3
PhosPhoSitePlusQ4JDL3
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (EBI)Prot-tyrosine_phosphatase-like    Tyr/Dual-sp_Pase    Tyr_Pase_AS    Tyr_Pase_rcpt/non-rcpt   
Domain families : Pfam (Sanger)Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00102   
Domain families : Smart (EMBL)PTPc (SM00194)  
Conserved Domain (NCBI)PTPN20
DMDM Disease mutations26095
Blocks (Seattle)PTPN20
SuperfamilyQ4JDL3
Human Protein AtlasENSG00000204179
Peptide AtlasQ4JDL3
HPRD10898
IPIIPI00294644   IPI00619950   IPI00619972   IPI00737076   IPI00741003   IPI00854661   IPI00854704   IPI00735509   IPI00854625   IPI00643067   IPI00854794   IPI00735238   IPI00181741   IPI00740604   IPI00854771   IPI00644244   IPI00872243   IPI00872528   IPI00739138   IPI01011098   IPI01012654   IPI00967657   IPI00965800   IPI00967761   IPI00967803   
Protein Interaction databases
DIP (DOE-UCLA)Q4JDL3
IntAct (EBI)Q4JDL3
FunCoupENSG00000204179
BioGRIDPTPN20
STRING (EMBL)PTPN20
ZODIACPTPN20
Ontologies - Pathways
QuickGOQ4JDL3
Ontology : AmiGOprotein tyrosine phosphatase activity  nucleus  cytoplasm  microtubule organizing center  microtubule  peptidyl-tyrosine dephosphorylation  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  nucleus  cytoplasm  microtubule organizing center  microtubule  peptidyl-tyrosine dephosphorylation  
NDEx NetworkPTPN20
Atlas of Cancer Signalling NetworkPTPN20
Wikipedia pathwaysPTPN20
Orthology - Evolution
OrthoDB26095
GeneTree (enSembl)ENSG00000204179
Phylogenetic Trees/Animal Genes : TreeFamPTPN20
HOVERGENQ4JDL3
HOGENOMQ4JDL3
Homologs : HomoloGenePTPN20
Homology/Alignments : Family Browser (UCSC)PTPN20
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTPN20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTPN20
dbVarPTPN20
ClinVarPTPN20
1000_GenomesPTPN20 
Exome Variant ServerPTPN20
ExAC (Exome Aggregation Consortium)PTPN20 (select the gene name)
Genetic variants : HAPMAP26095
Genomic Variants (DGV)PTPN20 [DGVbeta]
DECIPHER (Syndromes)10:46550123-46620058  ENSG00000204179
CONAN: Copy Number AnalysisPTPN20 
Mutations
ICGC Data PortalPTPN20 
TCGA Data PortalPTPN20 
Broad Tumor PortalPTPN20
OASIS PortalPTPN20 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPTPN20
BioMutasearch PTPN20
DgiDB (Drug Gene Interaction Database)PTPN20
DoCM (Curated mutations)PTPN20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTPN20 (select a term)
intoGenPTPN20
Cancer3DPTPN20(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610630    610631   
Orphanet
MedgenPTPN20
Genetic Testing Registry PTPN20
NextProtQ4JDL3 [Medical]
TSGene26095
GENETestsPTPN20
Huge Navigator PTPN20 [HugePedia]
snp3D : Map Gene to Disease26095
BioCentury BCIQPTPN20
ClinGenPTPN20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26095
Chemical/Pharm GKB GenePA134863260
Clinical trialPTPN20
Miscellaneous
canSAR (ICR)PTPN20 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTPN20
EVEXPTPN20
GoPubMedPTPN20
iHOPPTPN20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:40:12 CET 2017

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