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PTPN9 (protein tyrosine phosphatase, non-receptor type 9)

Identity

Other namesMEG2
PTPMEG2
HGNC (Hugo) PTPN9
LocusID (NCBI) 5780
Location 15q24.2
Location_base_pair Starts at 75759462 and ends at 75871632 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)PTPN9   9661
Cards
Entrez_Gene (NCBI)PTPN9  5780  protein tyrosine phosphatase, non-receptor type 9
GeneCards (Weizmann)PTPN9
Ensembl (Hinxton)ENSG00000169410 [Gene_View]  chr15:75759462-75871632 [Contig_View]  PTPN9 [Vega]
ICGC DataPortalENSG00000169410
cBioPortalPTPN9
AceView (NCBI)PTPN9
Genatlas (Paris)PTPN9
WikiGenes5780
SOURCE (Princeton)NM_002833
Genomic and cartography
GoldenPath (UCSC)PTPN9  -  15q24.2   chr15:75759462-75871632 -  15q24.2   [Description]    (hg19-Feb_2009)
EnsemblPTPN9 - 15q24.2 [CytoView]
Mapping of homologs : NCBIPTPN9 [Mapview]
OMIM600768   
Gene and transcription
Genbank (Entrez)BC010863 BC071574 BT007405 DQ890986 M83738
RefSeq transcript (Entrez)NM_002833
RefSeq genomic (Entrez)AC_000147 NC_000015 NC_018926 NT_010194 NW_001838219 NW_004929398
Consensus coding sequences : CCDS (NCBI)PTPN9
Cluster EST : UnigeneHs.445775 [ NCBI ]
CGAP (NCI)Hs.445775
Alternative Splicing : Fast-db (Paris)GSHG0010600
Alternative Splicing GalleryENSG00000169410
Gene ExpressionPTPN9 [ NCBI-GEO ]     PTPN9 [ SEEK ]   PTPN9 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43378 (Uniprot)
NextProtP43378  [Medical]
With graphics : InterProP43378
Splice isoforms : SwissVarP43378 (Swissvar)
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.483.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)CRAL_TRIO (PS50191)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (EBI)CRAL-TRIO_dom [organisation]   CRAL/TRIO_N_dom [organisation]   Prot-tyrosine_phosphatase-like [organisation]   Tyr/Dual-sp_Pase [organisation]   Tyr_Pase_AS [organisation]   Tyr_Pase_rcpt/non-rcpt [organisation]  
Related proteins : CluSTrP43378
Domain families : Pfam (Sanger)CRAL_TRIO (PF00650)    CRAL_TRIO_N (PF03765)    Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00650    pfam03765    pfam00102   
Domain families : Smart (EMBL)CRAL_TRIO_N (SM01100)  PTPc (SM00194)  SEC14 (SM00516)  
DMDM Disease mutations5780
Blocks (Seattle)P43378
PDB (SRS)2PA5    4GE2    4GE5    4GE6    4ICZ   
PDB (PDBSum)2PA5    4GE2    4GE5    4GE6    4ICZ   
PDB (IMB)2PA5    4GE2    4GE5    4GE6    4ICZ   
PDB (RSDB)2PA5    4GE2    4GE5    4GE6    4ICZ   
Human Protein AtlasENSG00000169410 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP43378
HPRD02864
IPIIPI00852804   IPI01010466   
Protein Interaction databases
DIP (DOE-UCLA)P43378
IntAct (EBI)P43378
FunCoupENSG00000169410
BioGRIDPTPN9
InParanoidP43378
Interologous Interaction database P43378
IntegromeDBPTPN9
STRING (EMBL)PTPN9
Ontologies - Pathways
Ontology : AmiGOprotein tyrosine phosphatase activity  non-membrane spanning protein tyrosine phosphatase activity  protein binding  cytoplasm  protein dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  non-membrane spanning protein tyrosine phosphatase activity  protein binding  cytoplasm  protein dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  peptidyl-tyrosine dephosphorylation  
Protein Interaction DatabasePTPN9
Wikipedia pathwaysPTPN9
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)PTPN9
snp3D : Map Gene to Disease5780
SNP (GeneSNP Utah)PTPN9
SNP : HGBasePTPN9
Genetic variants : HAPMAPPTPN9
Exome VariantPTPN9
1000_GenomesPTPN9 
ICGC programENSG00000169410 
Somatic Mutations in Cancer : COSMICPTPN9 
CONAN: Copy Number AnalysisPTPN9 
Mutations and Diseases : HGMDPTPN9
Mutations and Diseases : intOGenPTPN9
Genomic VariantsPTPN9  PTPN9 [DGVbeta]
dbVarPTPN9
ClinVarPTPN9
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM600768   
MedgenPTPN9
GENETestsPTPN9
Disease Genetic AssociationPTPN9
Huge Navigator PTPN9 [HugePedia]  PTPN9 [HugeCancerGEM]
General knowledge
Homologs : HomoloGenePTPN9
Homology/Alignments : Family Browser (UCSC)PTPN9
Phylogenetic Trees/Animal Genes : TreeFamPTPN9
Chemical/Protein Interactions : CTD5780
Chemical/Pharm GKB GenePA34005
Clinical trialPTPN9
Cancer Resource (Charite)ENSG00000169410
Other databases
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
CoreMinePTPN9
iHOPPTPN9
OncoSearchPTPN9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 17:01:43 CEST 2014

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