PTPRE (protein tyrosine phosphatase receptor type E)

2003-12-01  

Identity

HGNC
LOCATION
10q26.2
LOCUSID
ALIAS
HPTPE,PTPE,R-PTP-EPSILON
FUSION GENES

Other Information

Locus ID:

NCBI: 5791
MIM: 600926
HGNC: 9669
Ensembl: ENSG00000132334

Variants:

dbSNP: 5791
ClinVar: 5791
TCGA: ENSG00000132334
COSMIC: PTPRE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132334ENST00000254667P23469
ENSG00000132334ENST00000306042P23469
ENSG00000132334ENST00000442830Q5VWH6
ENSG00000132334ENST00000455661Q5VWH5
ENSG00000132334ENST00000467366S4R3X3
ENSG00000132334ENST00000471218S4R3B0
ENSG00000132334ENST00000479896S4R2Y5
ENSG00000132334ENST00000495530S4R448

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366544632023Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway.3
366544632023Receptor Type Protein Tyrosine Phosphatase Epsilon (PTPRE) Plays an Oncogenic Role in Thyroid Carcinoma by Activating the AKT and ERK1/2 Signaling Pathway.3
317229792020RPTPε promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation.4
317229792020RPTPε promotes M2-polarized macrophage migration through ROCK2 signaling and podosome formation.4
282350432017Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo.11
282350432017Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo.11
221170742012Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells.11
221170742012Epidermal growth factor receptor (EGFR)-mediated positive feedback of protein-tyrosine phosphatase epsilon (PTPepsilon) on ERK1/2 and AKT protein pathways is required for survival of human breast cancer cells.11
217344002011Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.17
217344002011Attempted replication of 50 reported asthma risk genes identifies a SNP in RAD50 as associated with childhood atopic asthma.17
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.52
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.52
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
180939732008Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling.8

Citation

Dessen P

PTPRE (protein tyrosine phosphatase receptor type E)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41928/ptpre