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PTPRE (protein tyrosine phosphatase receptor type E)

Identity

Alias (NCBI)HPTPE
PTPE
R-PTP-EPSILON
HGNC (Hugo) PTPRE
HGNC Alias symbPTPE
LocusID (NCBI) 5791
Atlas_Id 41928
Location 10q26.2  [Link to chromosome band 10q26]
Location_base_pair Starts at 128047612 and ends at 128085855 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GRK5 (10q26.11) / PTPRE (10q26.2)NCOA2 (8q13.3) / PTPRE (10q26.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)PTPRE   9669
Cards
Entrez_Gene (NCBI)PTPRE    protein tyrosine phosphatase receptor type E
AliasesHPTPE; PTPE; R-PTP-EPSILON
GeneCards (Weizmann)PTPRE
Ensembl hg19 (Hinxton)ENSG00000132334 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132334 [Gene_View]  ENSG00000132334 [Sequence]  chr10:128047612-128085855 [Contig_View]  PTPRE [Vega]
ICGC DataPortalENSG00000132334
TCGA cBioPortalPTPRE
AceView (NCBI)PTPRE
Genatlas (Paris)PTPRE
SOURCE (Princeton)PTPRE
Genetics Home Reference (NIH)PTPRE
Genomic and cartography
GoldenPath hg38 (UCSC)PTPRE  -     chr10:128047612-128085855 +  10q26.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PTPRE  -     10q26.2   [Description]    (hg19-Feb_2009)
GoldenPathPTPRE - 10q26.2 [CytoView hg19]  PTPRE - 10q26.2 [CytoView hg38]
ImmunoBaseENSG00000132334
Genome Data Viewer NCBIPTPRE [Mapview hg19]  
OMIM600926   
Gene and transcription
Genbank (Entrez)AA362195 AF406557 AJ315969 AJ430580 AK001335
RefSeq transcript (Entrez)NM_001316676 NM_001316677 NM_001323354 NM_001323355 NM_001323356 NM_001323357 NM_006504 NM_130435
Consensus coding sequences : CCDS (NCBI)PTPRE
Gene ExpressionPTPRE [ NCBI-GEO ]   PTPRE [ EBI - ARRAY_EXPRESS ]   PTPRE [ SEEK ]   PTPRE [ MEM ]
Gene Expression Viewer (FireBrowse)PTPRE [ Firebrowse - Broad ]
GenevisibleExpression of PTPRE in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5791
GTEX Portal (Tissue expression)PTPRE
Human Protein AtlasENSG00000132334-PTPRE [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23469   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23469  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23469
Catalytic activity : Enzyme3.1.3.48 [ Enzyme-Expasy ]   3.1.3.483.1.3.48 [ IntEnz-EBI ]   3.1.3.48 [ BRENDA ]   3.1.3.48 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusP23469
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (EBI)Prot-tyrosine_phosphatase-like    PTPase_domain    Tyr_Pase_AS    Tyr_Pase_cat    Tyr_Pase_rcpt_a/e-type    TYR_PHOSPHATASE_dom   
Domain families : Pfam (Sanger)Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00102   
Domain families : Smart (EMBL)PTPc (SM00194)  PTPc_motif (SM00404)  
Conserved Domain (NCBI)PTPRE
PDB (RSDB)2JJD    6D3F    6D4D    6D4F   
PDB Europe2JJD    6D3F    6D4D    6D4F   
PDB (PDBSum)2JJD    6D3F    6D4D    6D4F   
PDB (IMB)2JJD    6D3F    6D4D    6D4F   
Structural Biology KnowledgeBase2JJD    6D3F    6D4D    6D4F   
SCOP (Structural Classification of Proteins)2JJD    6D3F    6D4D    6D4F   
CATH (Classification of proteins structures)2JJD    6D3F    6D4D    6D4F   
SuperfamilyP23469
AlphaFold pdb e-kbP23469   
Human Protein Atlas [tissue]ENSG00000132334-PTPRE [tissue]
HPRD02956
Protein Interaction databases
DIP (DOE-UCLA)P23469
IntAct (EBI)P23469
BioGRIDPTPRE
STRING (EMBL)PTPRE
ZODIACPTPRE
Ontologies - Pathways
QuickGOP23469
Ontology : AmiGOprotein tyrosine phosphatase activity  transmembrane receptor protein tyrosine phosphatase activity  protein binding  nucleus  cytoplasm  plasma membrane  protein dephosphorylation  integral component of membrane  peptidyl-tyrosine dephosphorylation  negative regulation of insulin receptor signaling pathway  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  transmembrane receptor protein tyrosine phosphatase activity  protein binding  nucleus  cytoplasm  plasma membrane  protein dephosphorylation  integral component of membrane  peptidyl-tyrosine dephosphorylation  negative regulation of insulin receptor signaling pathway  
NDEx NetworkPTPRE
Atlas of Cancer Signalling NetworkPTPRE
Wikipedia pathwaysPTPRE
Orthology - Evolution
OrthoDB5791
GeneTree (enSembl)ENSG00000132334
Phylogenetic Trees/Animal Genes : TreeFamPTPRE
Homologs : HomoloGenePTPRE
Homology/Alignments : Family Browser (UCSC)PTPRE
Gene fusions - Rearrangements
Fusion : QuiverPTPRE
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTPRE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTPRE
dbVarPTPRE
ClinVarPTPRE
MonarchPTPRE
1000_GenomesPTPRE 
Exome Variant ServerPTPRE
GNOMAD BrowserENSG00000132334
Varsome BrowserPTPRE
ACMGPTPRE variants
VarityP23469
Genomic Variants (DGV)PTPRE [DGVbeta]
DECIPHERPTPRE [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPTPRE 
Mutations
ICGC Data PortalPTPRE 
TCGA Data PortalPTPRE 
Broad Tumor PortalPTPRE
OASIS PortalPTPRE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICPTPRE  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DPTPRE
Mutations and Diseases : HGMDPTPRE
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaPTPRE
DgiDB (Drug Gene Interaction Database)PTPRE
DoCM (Curated mutations)PTPRE
CIViC (Clinical Interpretations of Variants in Cancer)PTPRE
Cancer3DPTPRE
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600926   
Orphanet
DisGeNETPTPRE
MedgenPTPRE
Genetic Testing Registry PTPRE
NextProtP23469 [Medical]
GENETestsPTPRE
Target ValidationPTPRE
Huge Navigator PTPRE [HugePedia]
ClinGenPTPRE
Clinical trials, drugs, therapy
MyCancerGenomePTPRE
Protein Interactions : CTDPTPRE
Pharm GKB GenePA34014
PharosP23469
Clinical trialPTPRE
Miscellaneous
canSAR (ICR)PTPRE
HarmonizomePTPRE
DataMed IndexPTPRE
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXPTPRE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:27:31 CEST 2021

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