Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

PTPRQ (protein tyrosine phosphatase, receptor type Q)

Identity

Alias_namesDFNB84
deafness
Other aliasDFNB84A
PTPGMC1
R-PTP-Q
HGNC (Hugo) PTPRQ
LocusID (NCBI) 374462
Atlas_Id 55852
Location 12q21.31  [Link to chromosome band 12q21]
Location_base_pair Starts at 80444346 and ends at 80680189 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC9B1 (4q24) / PTPRQ (12q21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PTPRQ   9679
Cards
Entrez_Gene (NCBI)PTPRQ  374462  protein tyrosine phosphatase, receptor type Q
AliasesDFNB84; DFNB84A; PTPGMC1; R-PTP-Q
GeneCards (Weizmann)PTPRQ
Ensembl hg19 (Hinxton)ENSG00000139304 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139304 [Gene_View]  chr12:80444346-80680189 [Contig_View]  PTPRQ [Vega]
ICGC DataPortalENSG00000139304
TCGA cBioPortalPTPRQ
AceView (NCBI)PTPRQ
Genatlas (Paris)PTPRQ
WikiGenes374462
SOURCE (Princeton)PTPRQ
Genetics Home Reference (NIH)PTPRQ
Genomic and cartography
GoldenPath hg38 (UCSC)PTPRQ  -     chr12:80444346-80680189 +  12q21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PTPRQ  -     12q21.31   [Description]    (hg19-Feb_2009)
EnsemblPTPRQ - 12q21.31 [CytoView hg19]  PTPRQ - 12q21.31 [CytoView hg38]
Mapping of homologs : NCBIPTPRQ [Mapview hg19]  PTPRQ [Mapview hg38]
OMIM603317   613391   
Gene and transcription
Genbank (Entrez)AF169351 BM750287 DA545412 DB305536 DB318211
RefSeq transcript (Entrez)NM_001145026
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PTPRQ
Cluster EST : UnigeneHs.539284 [ NCBI ]
CGAP (NCI)Hs.539284
Alternative Splicing GalleryENSG00000139304
Gene ExpressionPTPRQ [ NCBI-GEO ]   PTPRQ [ EBI - ARRAY_EXPRESS ]   PTPRQ [ SEEK ]   PTPRQ [ MEM ]
Gene Expression Viewer (FireBrowse)PTPRQ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)374462
GTEX Portal (Tissue expression)PTPRQ
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UMZ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UMZ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UMZ3
Splice isoforms : SwissVarQ9UMZ3
Catalytic activity : Enzyme3.1.3.- [ Enzyme-Expasy ]   3.1.3.-3.1.3.- [ IntEnz-EBI ]   3.1.3.- [ BRENDA ]   3.1.3.- [ KEGG ]   
PhosPhoSitePlusQ9UMZ3
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    TYR_PHOSPHATASE_1 (PS00383)    TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_PTP (PS50055)   
Domains : Interpro (EBI)FN3_dom    Ig-like_fold    Prot-tyrosine_phosphatase-like    PTPase_domain    PTPRQ    Tyr_Pase_AS    Tyr_Pase_cat    TYR_PHOSPHATASE_dom   
Domain families : Pfam (Sanger)fn3 (PF00041)    Y_phosphatase (PF00102)   
Domain families : Pfam (NCBI)pfam00041    pfam00102   
Domain families : Smart (EMBL)FN3 (SM00060)  PTPc (SM00194)  PTPc_motif (SM00404)  
Conserved Domain (NCBI)PTPRQ
DMDM Disease mutations374462
Blocks (Seattle)PTPRQ
PDB (SRS)4IKC   
PDB (PDBSum)4IKC   
PDB (IMB)4IKC   
PDB (RSDB)4IKC   
Structural Biology KnowledgeBase4IKC   
SCOP (Structural Classification of Proteins)4IKC   
CATH (Classification of proteins structures)4IKC   
SuperfamilyQ9UMZ3
Human Protein AtlasENSG00000139304
Peptide AtlasQ9UMZ3
IPIIPI00741536   IPI01022684   IPI01021160   IPI00979188   
Protein Interaction databases
DIP (DOE-UCLA)Q9UMZ3
IntAct (EBI)Q9UMZ3
FunCoupENSG00000139304
BioGRIDPTPRQ
STRING (EMBL)PTPRQ
ZODIACPTPRQ
Ontologies - Pathways
QuickGOQ9UMZ3
Ontology : AmiGOprotein tyrosine phosphatase activity  integral component of membrane  cell differentiation  peptidyl-tyrosine dephosphorylation  inner ear morphogenesis  regulation of fat cell differentiation  phosphatidylinositol dephosphorylation  
Ontology : EGO-EBIprotein tyrosine phosphatase activity  integral component of membrane  cell differentiation  peptidyl-tyrosine dephosphorylation  inner ear morphogenesis  regulation of fat cell differentiation  phosphatidylinositol dephosphorylation  
NDEx NetworkPTPRQ
Atlas of Cancer Signalling NetworkPTPRQ
Wikipedia pathwaysPTPRQ
Orthology - Evolution
OrthoDB374462
GeneTree (enSembl)ENSG00000139304
Phylogenetic Trees/Animal Genes : TreeFamPTPRQ
HOVERGENQ9UMZ3
HOGENOMQ9UMZ3
Homologs : HomoloGenePTPRQ
Homology/Alignments : Family Browser (UCSC)PTPRQ
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPTPRQ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PTPRQ
dbVarPTPRQ
ClinVarPTPRQ
1000_GenomesPTPRQ 
Exome Variant ServerPTPRQ
ExAC (Exome Aggregation Consortium)PTPRQ (select the gene name)
Genetic variants : HAPMAP374462
Genomic Variants (DGV)PTPRQ [DGVbeta]
DECIPHERPTPRQ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPTPRQ 
Mutations
ICGC Data PortalPTPRQ 
TCGA Data PortalPTPRQ 
Broad Tumor PortalPTPRQ
OASIS PortalPTPRQ [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPTPRQ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch PTPRQ
DgiDB (Drug Gene Interaction Database)PTPRQ
DoCM (Curated mutations)PTPRQ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PTPRQ (select a term)
intoGenPTPRQ
Cancer3DPTPRQ(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603317    613391   
Orphanet12047   
MedgenPTPRQ
Genetic Testing Registry PTPRQ
NextProtQ9UMZ3 [Medical]
TSGene374462
GENETestsPTPRQ
Target ValidationPTPRQ
Huge Navigator PTPRQ [HugePedia]
snp3D : Map Gene to Disease374462
BioCentury BCIQPTPRQ
ClinGenPTPRQ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD374462
Chemical/Pharm GKB GenePA164742315
Clinical trialPTPRQ
Miscellaneous
canSAR (ICR)PTPRQ (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePTPRQ
EVEXPTPRQ
GoPubMedPTPRQ
iHOPPTPRQ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:27:17 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.