PTPRS (protein tyrosine phosphatase receptor type S)

2003-12-01  

Identity

HGNC
PTPRS
LOCATION
19p13.3
LOCUSID
5802
ALIAS
PTPSIGMA,R-PTP-S,R-PTP-sigma
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 5802
MIM: 601576
HGNC: 9681
Ensembl: ENSG00000105426

Variants:

dbSNP: 5802
ClinVar: 5802
TCGA: ENSG00000105426
COSMIC: PTPRS

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105426ENST00000262963G8JL96
ENSG00000105426ENST00000586065K7ERX4
ENSG00000105426ENST00000587303Q13332
ENSG00000105426ENST00000588012Q13332
ENSG00000105426ENST00000590509Q8NHS7
ENSG00000105426ENST00000591760K7ESP0
ENSG00000105426ENST00000592099Q13332

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Extracellular matrix organizationREACTOMER-HSA-1474244
ECM proteoglycansREACTOMER-HSA-3000178
SALM protein interactions at the synapsesREACTOMER-HSA-8849932
Protein-protein interactions at synapsesREACTOMER-HSA-6794362

References

Pubmed IDYearTitleCitations
389264562024PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's disease.0
389264562024PTPRS is a novel marker for early Tau pathology and synaptic integrity in Alzheimer's disease.0
359910092022High expression of protein tyrosine phosphatase receptor S (PTPRS) is an independent prognostic marker for cholangiocarcinoma.2
359910092022High expression of protein tyrosine phosphatase receptor S (PTPRS) is an independent prognostic marker for cholangiocarcinoma.2
333138792021Identification of PTPRσ-interacting proteins by proximity-labelling assay.4
333138792021Identification of PTPRσ-interacting proteins by proximity-labelling assay.4
314171832019BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis.8
314171832019BMP10 suppresses hepatocellular carcinoma progression via PTPRS-STAT3 axis.8
286146262018PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis.18
294207852018Interaction of receptor type of protein tyrosine phosphatase sigma (RPTPσ) with a glycosaminoglycan library.2
297459672018Expression and clinical relations of protein tyrosine phosphatase receptor type S in esophageal squamous cell carcinoma.2
299152912018PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation.12
286146262018PTPRS and PER3 methylation levels are associated with childhood obesity: results from a genome-wide methylation analysis.18
294207852018Interaction of receptor type of protein tyrosine phosphatase sigma (RPTPσ) with a glycosaminoglycan library.2
297459672018Expression and clinical relations of protein tyrosine phosphatase receptor type S in esophageal squamous cell carcinoma.2

Citation

Dessen P

PTPRS (protein tyrosine phosphatase receptor type S)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/41938/ptprs