PUM2 (pumilio RNA binding family member 2)

2003-05-01  

Identity

HGNC
LOCATION
2p24.1
LOCUSID
ALIAS
PUMH2,PUML2
FUSION GENES

Other Information

Locus ID:

NCBI: 23369
MIM: 607205
HGNC: 14958
Ensembl: ENSG00000055917

Variants:

dbSNP: 23369
ClinVar: 23369
TCGA: ENSG00000055917
COSMIC: PUM2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000055917ENST00000319801A0A0A0MR59
ENSG00000055917ENST00000338086Q8TB72
ENSG00000055917ENST00000361078Q8TB72
ENSG00000055917ENST00000403432Q8TB72
ENSG00000055917ENST00000424110C9JE24
ENSG00000055917ENST00000429419F8WD57
ENSG00000055917ENST00000432105F2Z366
ENSG00000055917ENST00000440577A0A0C4DG68
ENSG00000055917ENST00000442400C9JW01
ENSG00000055917ENST00000446940F2Z366

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
267248662016Noncoding RNA NORAD Regulates Genomic Stability by Sequestering PUMILIO Proteins.176
223455172012Pumilio facilitates miRNA regulation of the E2F3 oncogene.68
125115972003Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins.66
222313982012A conserved PUF-Ago-eEF1A complex attenuates translation elongation.66
156074252005Identification and characterization of RNA sequences to which human PUMILIO-2 (PUM2) and deleted in Azoospermia-like (DAZL) bind.36
213971872011Alternate modes of cognate RNA recognition by human PUMILIO proteins.27
282325822017PUMILIO/FOXP1 signaling drives expansion of hematopoietic stem/progenitor and leukemia cells.19
291655872018Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins.14
218001632011NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells.12
216495612012PUMILIO-2 is involved in the positive regulation of cellular proliferation in human adipose-derived stem cells.11

Citation

Dessen P

PUM2 (pumilio RNA binding family member 2)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/41950/pum2