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PUM3 (pumilio RNA binding family member 3)

Identity

Alias_namesKIAA0020
KIAA0020
Alias_symbol (synonym)XTP5
PEN
PUF6
hPUF-A
HA-8
Other aliasHLA-HA8
PUF-A
HGNC (Hugo) PUM3
LocusID (NCBI) 9933
Atlas_Id 77962
Location 9p24.2  [Link to chromosome band 9p24]
Location_base_pair Starts at 2804155 and ends at 2844130 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
GLIS3 (9p24.2) / PUM3 (9p24.2)PUM3 (9p24.2) / INS-IGF2 (11p15.5)PUM3 (9p24.2) / PUM3 (9p24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)PUM3   29676
Cards
Entrez_Gene (NCBI)PUM3  9933  pumilio RNA binding family member 3
AliasesHA-8; HLA-HA8; KIAA0020; PEN; 
PUF-A; PUF6; XTP5
GeneCards (Weizmann)PUM3
Ensembl hg19 (Hinxton)ENSG00000080608 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000080608 [Gene_View]  chr9:2804155-2844130 [Contig_View]  PUM3 [Vega]
ICGC DataPortalENSG00000080608
TCGA cBioPortalPUM3
AceView (NCBI)PUM3
Genatlas (Paris)PUM3
WikiGenes9933
SOURCE (Princeton)PUM3
Genetics Home Reference (NIH)PUM3
Genomic and cartography
GoldenPath hg38 (UCSC)PUM3  -     chr9:2804155-2844130 -  9p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)PUM3  -     9p24.2   [Description]    (hg19-Feb_2009)
EnsemblPUM3 - 9p24.2 [CytoView hg19]  PUM3 - 9p24.2 [CytoView hg38]
Mapping of homologs : NCBIPUM3 [Mapview hg19]  PUM3 [Mapview hg38]
OMIM609960   
Gene and transcription
Genbank (Entrez)AF490254 AK225953 AK292169 AK315531 AL832239
RefSeq transcript (Entrez)NM_001031691 NM_014878
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)PUM3
Cluster EST : UnigeneHs.493309 [ NCBI ]
CGAP (NCI)Hs.493309
Alternative Splicing GalleryENSG00000080608
Gene ExpressionPUM3 [ NCBI-GEO ]   PUM3 [ EBI - ARRAY_EXPRESS ]   PUM3 [ SEEK ]   PUM3 [ MEM ]
Gene Expression Viewer (FireBrowse)PUM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9933
GTEX Portal (Tissue expression)PUM3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15397   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15397  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15397
Splice isoforms : SwissVarQ15397
PhosPhoSitePlusQ15397
Domaine pattern : Prosite (Expaxy)PUM (PS50302)    PUM_HD (PS50303)   
Domains : Interpro (EBI)ARM-like    ARM-type_fold    CPL_dom    PUM-HD    Pumilio_RNA-bd_rpt   
Domain families : Pfam (Sanger)CPL (PF08144)   
Domain families : Pfam (NCBI)pfam08144   
Domain families : Smart (EMBL)Pumilio (SM00025)  
Conserved Domain (NCBI)PUM3
DMDM Disease mutations9933
Blocks (Seattle)PUM3
PDB (SRS)4WZR    4WZW   
PDB (PDBSum)4WZR    4WZW   
PDB (IMB)4WZR    4WZW   
PDB (RSDB)4WZR    4WZW   
Structural Biology KnowledgeBase4WZR    4WZW   
SCOP (Structural Classification of Proteins)4WZR    4WZW   
CATH (Classification of proteins structures)4WZR    4WZW   
SuperfamilyQ15397
Human Protein AtlasENSG00000080608
Peptide AtlasQ15397
HPRD08822
IPIIPI00791325   
Protein Interaction databases
DIP (DOE-UCLA)Q15397
IntAct (EBI)Q15397
FunCoupENSG00000080608
BioGRIDPUM3
STRING (EMBL)PUM3
ZODIACPUM3
Ontologies - Pathways
QuickGOQ15397
Ontology : AmiGODNA binding  RNA binding  mRNA binding  protein binding  nucleoplasm  chromosome  nucleolus  endoplasmic reticulum  regulation of translation  regulation of protein ADP-ribosylation  
Ontology : EGO-EBIDNA binding  RNA binding  mRNA binding  protein binding  nucleoplasm  chromosome  nucleolus  endoplasmic reticulum  regulation of translation  regulation of protein ADP-ribosylation  
NDEx NetworkPUM3
Atlas of Cancer Signalling NetworkPUM3
Wikipedia pathwaysPUM3
Orthology - Evolution
OrthoDB9933
GeneTree (enSembl)ENSG00000080608
Phylogenetic Trees/Animal Genes : TreeFamPUM3
HOVERGENQ15397
HOGENOMQ15397
Homologs : HomoloGenePUM3
Homology/Alignments : Family Browser (UCSC)PUM3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerPUM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)PUM3
dbVarPUM3
ClinVarPUM3
1000_GenomesPUM3 
Exome Variant ServerPUM3
ExAC (Exome Aggregation Consortium)PUM3 (select the gene name)
Genetic variants : HAPMAP9933
Genomic Variants (DGV)PUM3 [DGVbeta]
DECIPHERPUM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisPUM3 
Mutations
ICGC Data PortalPUM3 
TCGA Data PortalPUM3 
Broad Tumor PortalPUM3
OASIS PortalPUM3 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDPUM3
BioMutasearch PUM3
DgiDB (Drug Gene Interaction Database)PUM3
DoCM (Curated mutations)PUM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)PUM3 (select a term)
intoGenPUM3
Cancer3DPUM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609960   
Orphanet
MedgenPUM3
Genetic Testing Registry PUM3
NextProtQ15397 [Medical]
TSGene9933
GENETestsPUM3
Target ValidationPUM3
Huge Navigator PUM3 [HugePedia]
snp3D : Map Gene to Disease9933
BioCentury BCIQPUM3
ClinGenPUM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9933
Chemical/Pharm GKB GenePA134895115
Clinical trialPUM3
Miscellaneous
canSAR (ICR)PUM3 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMinePUM3
EVEXPUM3
GoPubMedPUM3
iHOPPUM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:37:54 CEST 2017

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